- Gestational Diabetes Research and Management
- Pancreatic function and diabetes
- Congenital Heart Disease Studies
- Diabetes Treatment and Management
- Diabetes Management and Research
- Diabetes and associated disorders
- Cardiac Arrhythmias and Treatments
- Bariatric Surgery and Outcomes
- Cardiomyopathy and Myosin Studies
- Pregnancy and preeclampsia studies
- Cardiovascular Function and Risk Factors
- Obesity, Physical Activity, Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Nuclear Structure and Function
- ECG Monitoring and Analysis
- Kawasaki Disease and Coronary Complications
- Cardiac electrophysiology and arrhythmias
- Coronary Artery Anomalies
- Adrenal and Paraganglionic Tumors
- Cardiac Valve Diseases and Treatments
- Pregnancy and Medication Impact
- RNA modifications and cancer
- Cardiac Structural Anomalies and Repair
- CRISPR and Genetic Engineering
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
King's College London
2018-2024
Evelina London Children's Healthcare
2019-2024
Box Hill Institute
2023
Royal Brompton & Harefield NHS Foundation Trust
2021-2023
Royal Brompton Hospital
2018-2021
Alder Hey Children's Hospital
2018-2020
University of Liverpool
2017-2020
Liverpool John Moores University
2020
Imperial College London
2019
Great Ormond Street Hospital
2018
The Ozaki procedure is a surgical technique for patients with significant aortic stenosis or regurgitation both where valve repair cannot be performed. Individual cusps are cut from glutaraldehyde-treated autologous pericardium bovine and implanted into the position. Encouraging results have been reported within adult population. There limited published data on success of this in younger patients.We present series five children young adults who underwent neoaortic made CardioCel,...
Abstract Aims The 12-lead electrocardiogram (ECG) is routinely performed in children with hypertrophic cardiomyopathy (HCM). An ECG risk score has been suggested as a useful tool for stratification, but this not independently validated. This aim of study was to describe the phenotype childhood HCM large, international, multi-centre cohort and investigate its role prediction arrhythmic events. Methods results Data from 356 patients mean age 10.1 years (±4.5) were collected retrospective,...
Prenatal diagnosis of coarctation the aorta (CoA) is associated with reduced mortality and morbidity, however, accurate prenatal prediction remains challenging. To date, studies have used retrospective measurements outflow tracts to evaluate their potential predict CoA. Our primary objective was prospectively acquired in fetuses prenatally suspected A secondary aim report postnatal prevalence bicuspid aortic valve this cohort.Pregnancies suspicion isolated CoA a minimum 6 months' follow-up...
COVID-19 has caused significant worldwide morbidity and mortality. Congenital heart disease (CHD) is likely to increase vulnerability understanding the predictors of adverse outcomes key optimising care.
Establish whether the reliable measurement of cardiac time intervals fetal ECG can be automated and to address this approach could used investigate large datasets.Retrospective observational study.Teaching hospitals in London UK, Nottingham UK New York USA.Singleton pregnancies with no known abnormality.Archived ECG's performed using MonicaAN24 monitor. A single (PQRST) complex was generated from 5000 signal-averaged beats electrical measured an way manually.Validation a newly developed...
Cardiovascular magnetic resonance (CMR) derived fractal analysis of the left ventricle (LV) has been shown in adults to be a useful quantitative measure trabeculation with high reproducibility and accuracy for diagnosis LV non-compaction (LVNC). The aim this study was investigate utility feasibility children.