A5069797539- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Gut microbiota and health
- Intestinal and Peritoneal Adhesions
- Obesity and Health Practices
- Diabetes Treatment and Management
- Gastroesophageal reflux and treatments
- Eating Disorders and Behaviors
- Body Contouring and Surgery
- Social and Demographic Issues in Germany
- Cardiovascular Disease and Adiposity
- European history and politics
- Cardiac, Anesthesia and Surgical Outcomes
- Social Policy and Reform Studies
- Global Health Care Issues
- Attachment and Relationship Dynamics
- European Socioeconomic and Political Studies
- Gastric Cancer Management and Outcomes
- Hernia repair and management
- European Law and Migration
- Obesity, Physical Activity, Diet
- Pancreatitis Pathology and Treatment
- Behavioral Health and Interventions
- Medical and Health Sciences Research
- Pharmacology and Obesity Treatment
Amsterdam University Medical Centers
2020-2025
Spaarne Ziekenhuis
2020-2025
Spaarne Gasthuis
2020-2025
University of Amsterdam
2021
Amsterdam UMC Location University of Amsterdam
2020
Prevalence of obesity and associated diseases, including type 2 diabetes mellitus, dyslipidaemia non-alcoholic fatty liver disease (NAFLD), are increasing. Underlying mechanisms, especially in humans, unclear. Bariatric surgery provides the unique opportunity to obtain biopsies portal vein blood-samples.The BARIA Study aims assess how microbiota their metabolites affect transcription key tissues clinical outcome obese subjects baseline anthropometric metabolic characteristics determine...
Abstract Purpose This study aimed to identify trajectories of BMI, obesity-specific health-related quality life (HR-QoL), and depression from pre-surgery 24 months post-bariatric metabolic surgery (BMS), explore their associations, addressing subgroup differences often hidden in group-level analyses. Method Patients with severe obesity ( n = 529) reported HR-QoL before undergoing BMS, at 12 post-operation. Latent Class Growth Analysis was used depression. Results BMI improved significantly...
Abstract Background Internal herniation (IH) is a potentially life-threatening complication after gastric bypass. Accurate diagnosis of IH remains challenging. This study aims to validate the Eindhoven2020 (EHV20) scoring system for ruling out and seeks improve its diagnostic accuracy through additional radiologic parameters. Methods Patients participating in prospective on abdominal pain bypass surgery were selected if CT scan was performed. scans scored following EHV20 containing ten signs...
Male patients are underrepresented in bariatric surgery (BS) despite a relatively equal proportion of men and women experiencing obesity.Differences frequency severity obesity-associated medical problems (OAMPs) between undergoing BS or control group (HELIUS [HEalthy Life In an Urban Setting]) were evaluated. The hypothesis was that less healthy than women.A cross-sectional study 2 cohorts 2013 (BS2013) 2019 (BS2019) with severe obesity from general population (HELIUS).Characteristics...
Abdominal pain after bariatric surgery (BS) is frequently observed. Despite numerous diagnostic tests, the cause of abdominal not always found.To quantify type and number tests performed in patients with BS evaluate burden their yield process.A center Netherlands.In this prospective study, we included who presented between December 1, 2020, 2021. All reoperations during one episode were scored using a standardized protocol.A total 441 included; 401 (90.9%) female, median time was 37.0 months...
Attachment avoidance and anxiety have been linked to overweight poor health behaviours, yet the mechanisms that underpin relationship between attachment behaviours are not fully understood. Self-esteem self-efficacy found differ styles, rendering these variables potential mediators of relationship. This longitudinal study investigated serial mediation preoperative 2-year post-operative through self-esteem self-efficacy.Participants were 263 bariatric surgery patients (75.7% females, aged...
Abstract Purpose Chronic pain and obesity often co-occur, negatively affecting one another psychological wellbeing. Pain wellbeing improve after bariatric metabolic surgery (BMS), however, it is unknown whether improves differently weight loss between patients with without chronic pain. We investigated associated greater functioning change BMS, comparing preoperative syndromes. Methods Depression, health-related quality of life, self-esteem, self-efficacy to exercise controlling eating...
Incretins, bile acids and the gut microbiome are involved in pathophysiology of obesity type 2 diabetes. The incretins glucagon-like peptide-1 glucose-dependent-insulinetrophic polypeptide, both influence beta-cell function, insulin glucose sensitivity, food intake. Studies have shown that concentrations change after bariatric surgery nowadays agonists administered as body weight regulating agents. Bile also play an important role glycemic metabolic regulation via multiple signaling...
Abstract Background Metabolic surgery induces rapid remission of type 2 diabetes mellitus (T2DM). There is a paucity high level evidence comparing the efficacy laparoscopic Roux-en-Y gastric bypass (RYGB) and one-anastomosis (OAGB) in glycemic control. Also, mechanisms that drive conversion T2DM severe obese subjects to euglycemia are poorly understood. Methods The DIABAR-trial an open, multi-center, randomized controlled clinical trial with 10 years follow-up which will be performed 220...
Chronic abdominal complaints after bariatric surgery may be explained by pancreatic exocrine insufficiency (PEI).We aimed to evaluate the clinical value of Pancreatic Exocrine Insufficiency Questionnaire (PEI-Q) as a screening tool identify patients with high probability having PEI.Outpatient clinic for surgery.Patients scheduled or follow-up appointment were asked complete PEI-Q and Gastrointestinal Quality Life Index questionnaire (GIQLI). Postoperative score (0,6) offered fecalelastase...
Abstract Purpose Roux-en-Y gastric bypasses (RYGB) are frequently accompanied by long-term gastrointestinal (GI) symptoms. Direct mechanistic insight into the causation of these symptoms is lacking, but changes in intestinal microbiome have been proposed to play a role. With this study, we aimed investigate whether microbial predisposition exists before RYGB which associated with GI during follow-up and evaluate groups involved. Materials Methods In total, 67 patients were included. Shotgun...
Abstract Purpose Long-term follow-up after bariatric surgery (BS) reveals high numbers of patients with abdominal pain that often remains unexplained. The aim this prospective study was to give an overview diagnoses for pain, percentage unexplained complaints, number and yield visits, time establish a diagnosis. Materials Methods Patients who visited the Spaarne Gasthuis Hospital, Netherlands, between December 2020 2021 BS, were eligible followed throughout entire episode pain. Distinction...