A5100342110- Plant Gene Expression Analysis
- Plant Molecular Biology Research
- Food Quality and Safety Studies
- Plant-Microbe Interactions and Immunity
- Thyroid Cancer Diagnosis and Treatment
- Agriculture, Soil, Plant Science
- Photosynthetic Processes and Mechanisms
- Plant nutrient uptake and metabolism
- Thyroid Disorders and Treatments
- Plant Stress Responses and Tolerance
- Fungal and yeast genetics research
- Diabetes Management and Research
- Parallel Computing and Optimization Techniques
- Nutrition, Health and Food Behavior
- Hair Growth and Disorders
- Gastrointestinal disorders and treatments
- Ruminant Nutrition and Digestive Physiology
- Fetal and Pediatric Neurological Disorders
- Soft tissue tumor case studies
- Renal Diseases and Glomerulopathies
- Advanced Power Generation Technologies
- Endoplasmic Reticulum Stress and Disease
- Dermatology and Skin Diseases
- Dermatological and COVID-19 studies
- Meat and Animal Product Quality
Gyeongsang National University
2004-2017
Changwon National University
2017
National Institute of Animal Science
2012-2013
United States Department of Agriculture
2010
University of Nevada, Reno
2010
Calmodulin (CaM), a ubiquitous calcium-binding protein, regulates diverse cellular functions by modulating the activity of variety enzymes and proteins. Plants express numerous CaM isoforms that exhibit differential activation and/or inhibition CaM-dependent in vitro. However, specific biological plant are not well known. In this study, we isolated cDNA encoding binding transcription factor, MYB2, expression salt- dehydration-responsive genes Arabidopsis. This was achieved using...
Abstract Calcium (Ca2+) signals regulate many aspects of plant development, including a programmed cell death pathway that protects plants from pathogens (hypersensitive response). Cytosolic Ca2+ result combined action influx through channels and efflux pumps cotransporters. Plants utilize calmodulin-activated (autoinhibited Ca2+-ATPase [ACA]) at the plasma membrane, endoplasmic reticulum, vacuole. Here, we show double knockout mutation vacuolar ACA4 ACA11 in Arabidopsis (Arabidopsis...
Calmodulin (CaM), a ubiquitous calcium-binding protein, regulates diverse cellular functions by modulating the activity of variety proteins. However, little is known about how CaM directly transcription. Screening an Arabidopsis cDNA expression library using horseradish peroxidase-conjugated calmodulin as probe identified calmodulin-binding NAC protein (CBNAC). Using gel overlay assays, Ca2+-dependent CaM-binding domain was in C terminus this protein. Specific binding to corroborated...
In plant cells, the vacuole functions as a major calcium store. Although calmodulin‐regulated Ca 2+ ‐ATPase (ACA4) is known to be present in prevacuolar compartments, presence of an ACA‐type mature cell has not been verified. Here we provide evidence that ACA11 localizes membrane. tagged with GFP was expressed stable transgenic plants, and visualized root cells protoplasts by confocal microscopy. A function for confirmed complementation yeast mutants. calmodulin binding domain identified...
The mitogen-activated protein kinases (MAPKs) are key signal transduction molecules, which respond to various external stimuli. MAPK phosphatases (MKPs) known be negative regulators of MAPKs in eukaryotes. We screened an <i>Arabidopsis</i> cDNA library using horseradish peroxidase-conjugated calmodulin (CaM), and isolated AtMKP1 as a CaM-binding protein. Recently, tobacco NtMKP1 rice OsMKP1, two orthologs AtMKP1, were reported bind CaM via single putative binding domain (CaMBD). However,...
Voltage-dependent anion channels (VDACs) are reported to be porin-type, β-barrel diffusion pores. They prominently localized in the outer mitochondrial membrane and involved metabolite exchange between organelle cytosol. In this study, we have investigated a family of VDAC isoforms Arabidopsis thaliana (AtVDAC). We shown that heterologous expression AtVDAC proteins can functionally complement yeast mutant lacking endogenous gene. AtVDACs tagged with GFP were mitochondria both plant cells....
Thyrotoxicosis influences cardiovascular hemodynamics and can induce coronary vasospasm. Patients with thyrotoxicosis-induced acute myocardial infarction (AMI) are unusual almost all reported cases have been associated Graves' disease. painless thyroiditis show a thyrotoxic phase during the early stages. Here we describe very rare case of thyrotoxicosis thyroiditis-induced AMI.A 35-year-old Korean man visited emergency room for 2-hour duration typical AMI chest pain. The patient did not any...
Calmodulin (CaM), a key Ca(2+) sensor in eukaryotes, regulates diverse cellular processes by interacting with many proteins. To identify Ca(2+)/CaM-mediated signaling components, we screened an Arabidopsis expression library horseradish peroxidase-conjugated calmodulin2 (AtCaM2) and isolated homolog of the UBP6 deubiquitinating enzyme family (AtUBP6) containing Ca(2+)-dependent CaM-binding domain (CaMBD). The activity AtUBP6 CaMBD was confirmed CaM mobility shift assay, phosphodiesterase...
Polycystic ovary syndrome (PCOS) and Graves' disease are the common causes of menstrual irregularity leading to infertility in women child-bearing age. A 21-year-old female patient visited us with complaints oligomenorrhea hand tremor. She was diagnosed as having PCOS hyperthyroid disease, simultaneously. had low body weight (BMI: 16.4 kg/m2), mild hirsutism, thyrotoxicosis. The treated anti-thyroid drug beta-blocker for about two years, then recovered normal thyroid function. Although some...
We describe a 47-year-old woman with severe coronary vasospasm induced by hyperthyroidism. The patient complained of anginal chest pain without specific characteristics thyrotoxicosis. Coronary arteriography was performed and revealed 90% stenosis both the left right os. She treated emergent artery bypass graft surgery. Postoperatively, she exhibited comatose mentality. Severe thyrotoxicosis indicated on thyroid function tests thyrotoxic storm diagnosed. Nineteen days after surgery following...
Calmodulin (CaM), a key Ca2+ sensor, regulates diverse cellular processes by modulating the activity of variety enzymes and proteins. However, little is known about biological function CaM in plant development. In this study, an ASYMMETRIC LEAVES1 (AS1) transcription factor was isolated as CaM-binding protein. AS1 contains two putative domains (CaMBDs) at N-terminus. Using domain mapping analysis, both predicted were identified authentic -dependent CaMBDs. We three hydrophobic amino acid...
Purpose:The aim of this study is to observe glycemic changes after emphasizing the importance lifestyle modification in patients with mild or moderately uncontrolled type 2 diabetes.Materials and Methods: We examined 51 diabetic 7.0-9.0%hemoglobin A1c (HbA1c) who preferred change their rather than followed recommendation medication change.At enrollment, subjects completed questionnaires about diet exercise.After 3 months, HbA1c levels were determined on accomplished.We divided into groups:...
We describe here the case of a 39-year-old woman with cortisol-producing adrenal adenoma and she presented endometrial hyperplasia hypertension without specific characteristics Cushing's syndrome. The patient had consulted gynecologist for menometrorrhagia 2 years prior to her referral was diagnosed hypertension. Her blood pressure lesion were refractory despite taking multiple antihypertensives repetitive dilation curettage progestin treatment. On admission, clinical examination revealed...
본 연구는 맥주박, 비지박 및 볏짚을 각각 이용하여 배합한 TMR을 한우 거세우에게 급여하였을 때 사양성적, 혈액성상 도체특성을 구명하고자 수행되었다. 시험구는 6개월령 거세우 24두(평균체중 168 kg)를 배합사료 볏짚 분리급여구(T1), 맥주박 첨가 TMR 급여구(T2), 급여구(T3) 급여구(T4)에 6두씩 완전임의 배치하여 총 22개월간 사양시험을 실시하여 28개월령에 도축하였다. 시험결과에서 체중은 육성기에서 비육전기까지 처리구들간 유의적인 차이는 없었다. 하지만, 종료시 체중에서 T4 처리구가 T2 처리구에 비해 유의적으로 높았다. 일당증체량은 육성기 비육중기에서 급여구가 T1에 높았지만(p<0.05), 전체평균에서는 차이가 건물섭취량은 급여구(T2, T3, T4)에서 높은 경향을 나타내었다. 사료요구율은 낮았다(p<0.05). 육량특성에서 도체중은 T1, T2, T3 처리구에서 389.0, 368.4 387.5 384.3 kg이었다. 등지방두께, 등심단면적...
A 23-year-old pregnant woman had a stillbirth at 30 weeks gestation due to abrupt diabetic ketoacidosis. The patient normal HbA1c, severe hyperglycemia, negative islet cell autoantibodies, and very low insulin secretion capacity. viral markers associated with fulminant type 1 diabetes were negative. patient's human leukocyte antigen genotypes DRB1*04:06 DQB1*03:01/05:02, not common subtypes for diabetes. This is the first Vietnamese mellitus.
BACKGROUNDIt is important to differentiate Graves' disease from that of painless thyroiditis in patients with thyrotoxicosis. In this study, we evaluated the usefulness total T3 free T4 ratio making a differential diagnosis between and thyroiditis. METHODS: We reviewed medical records thyrotoxic patients, who had been diagnosed or thyroiditis, October 2009 July 2011. assessed clinical characteristics, serum levels T3, T4, thyroid stimulating hormone, thyrotropin-binding inhibitory...
본 연구는 한우 암소 비육시 배합사료 급여형태가 발육, 혈액성상 및 도체특성에 미치는 영향을 구명하고자 수행하였다. 처리구는 제한급여 8개월(T1), 6개월 후 자유채식 2개월(T2) 제한 4개월 자유 4개월급여(T3)로 3처리 9반복으로 완전임의배치 하였다. 급여형태별 발육은 처리구간 유의적인 차이가 없었다. 그러나, 일당증체량은 T2 처리구(0.75 kg/d)가 다른 처리구(T1: 0.62 kg/d, T3: 0.72 kg/d)에 비해 높은 경향을 나타내었다. 건물섭취량은 차이는 없었지만 T1 처리구의 볏짚 섭취량이 처리구 보다 유의적으로 높았다(p<0.05). 사료요구량은 T1: 17.8, T2: 12.8 14.1 kg으로 인정되었다(p<0.05). 혈청 내 albumin, triglyceride, glucose GPT의 농도는 비육개시 6개월에서 8개월에 T3 처리구가 처리구에 높게 나타났다(p<0.05). 육량특성에서 도체중, 등지방두께 등심단면적은 처리 구간 유사한...