J.I. Lee

ORCID: 0000-0003-2740-2432
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Semiconductor Quantum Structures and Devices
  • Mesenchymal stem cell research
  • Pancreatic function and diabetes
  • Tissue Engineering and Regenerative Medicine
  • Osteoarthritis Treatment and Mechanisms
  • Advanced Semiconductor Detectors and Materials
  • Semiconductor Lasers and Optical Devices
  • Diabetes Management and Research
  • Semiconductor materials and devices
  • Photonic and Optical Devices
  • Electrospun Nanofibers in Biomedical Applications
  • Quantum Dots Synthesis And Properties
  • Periodontal Regeneration and Treatments
  • Advancements in Semiconductor Devices and Circuit Design
  • Urinary Bladder and Prostate Research
  • Knee injuries and reconstruction techniques
  • Silk-based biomaterials and applications
  • Prostate Cancer Diagnosis and Treatment
  • Diabetes and associated disorders
  • Pluripotent Stem Cells Research
  • Urologic and reproductive health conditions
  • Prostate Cancer Treatment and Research
  • 3D Printing in Biomedical Research
  • Advanced Data Compression Techniques
  • Neuroblastoma Research and Treatments

Columbia University
2013-2025

Konkuk University
2012-2024

Kyung Hee University
2023-2024

Chung-Ang University
2019

Korea Institute of Science and Technology
1992-2018

Seoul Veterans Hospital
2005-2016

Yonsei University
2008-2015

Institute of Biomedical Science
2015

Seoul National University Bundang Hospital
2014

Samsung Medical Center
2014

Abstract Background Although the clinical results of autologous chondrocyte implantation for articular cartilage defects have recently improved as a result advanced techniques based on tissue engineering procedures, problems with cell handling and scaffold imperfections remain to be solved. A new cell-sheet technique has been developed, is potentially able overcome these obstacles. Chondrocyte sheets applicable regeneration can prepared this using temperature-responsive culture dishes....

10.1186/1472-6750-9-17 article EN cc-by BMC Biotechnology 2009-03-06

Polymers are known to spontaneously produce microplastics (sizes 1 μm – 3 mm) and nanoplastics (10 nm μm). Still, the mechanisms by which environmentally-triggered Å-level random bond breaking events lead formation of these relatively large fragments unclear. Significantly, $$\approx$$ 70% commercial polymers semicrystalline, with a morphology comprised alternating crystalline amorphous layers, each tens nanometers thick. It is well-accepted that chain scission accumulate in phase. We show...

10.1038/s41467-025-58233-3 article EN cc-by-nc-nd Nature Communications 2025-03-28

Although it is energetically extremely unfavorable to have charged amino acid residues of a polypeptide in the hydrophobic environment membrane phospholipid bilayer, few such are found membrane-spanning regions proteins. Ion pairs (salt bridges) would be much more stable low dielectric media than single ionized residues. This paper provides indirect evidence for salt bridge between Asp-240 and Lys-319 lactose carrier Escherichia coli. When was changed alanine by site-directed mutagenesis,...

10.1016/s0021-9258(19)36751-1 article EN cc-by Journal of Biological Chemistry 1992-10-01

Objectives: The usefulness of a malleable penile prosthesis was evaluated in patients with spinal cord injury (SCI) by investigating the complications and patients’ satisfaction. Methods: A total 48 SCI, who underwent (AMS 600) insertion from 1990 to 2004 were reviewing medical records interviewing them via questionnaires. mean age 58.9 years, follow‐up period 11.7 years. In 23 patients, implantation carried out improve urinary management treat erectile dysfunction (ED). Results:...

10.1111/j.1442-2042.2008.02115.x article EN International Journal of Urology 2008-07-22

Adipose-derived stem cell (ADSC) transplantation has been proposed to improve cardiac function and acute myocardial infarction (AMI). Recently, sheet technology investigated for its potential applicability in injury. However, a detailed comparison of the functional recovery injured myocardium between sheets conventional injection not adequately examined. ADSCs were isolated from inguinal fat tissue ICR mice. Three groups AMI induction only (sham), intramyocardial (imADSC), ADSC (shADSC)...

10.1089/ten.tea.2016.0023 article EN Tissue Engineering Part A 2016-09-27

The term “immunoisolation” refers to the encapsulation of a graft in selectively permeable membrane. Encapsulation cellular grafts may provide way protect from immune attack without need for immunosuppressive agents. Although numerous types artificial materials have been used encapsulating membranes, their incomplete biocompatibility causes foreign body reaction against membranes. A new technique has developed, called cell sheet engineering using temperature-responsive culture dishes, that...

10.3727/000000008783907035 article EN Cell Transplantation 2008-01-01

Abstract Background Fluorescence correlation spectroscopy (FCS) provides information about translational diffusion of fluorescent molecules in tiny detection volumes at the single-molecule level. In normal states, cartilage tissue lacks vascularity, so chondrocyte metabolism depends on for molecular exchanges. The abundant extracellular matrix (ECM) is maintained by a limited number chondrocytes. ECM plays an important role regulation functions. this study, FCS was used to measure behaviors...

10.1186/1472-6750-11-19 article EN cc-by BMC Biotechnology 2011-03-02

Mesenchymal stem cell (MSC) therapy has been actively applied in veterinary regenerative medicine to treat various canine and feline diseases. With increasing emphasis on safe cell-based therapies, evaluations of their tumorigenic potential are great demand. However, a direct confirmation whether tumors originate from cells or host is not easily achievable. Additionally, previous studies evaluating injections high doses MSCs into nude mice did demonstrate tumor formation. Recent research...

10.3390/ani14070994 article EN cc-by Animals 2024-03-23

A superluminescent diode (SLD) using J-shaped ridge waveguide and chirped multiple InAs quantum dots (QDs) with three different energy bandgap wavelengths, which are controlled by QD size, is demonstrated. The fabricated SLDs exhibit high continuous wave output power of 32 mW wide spectral bandwidth up to 98 nm, covering the range 1084–1182 nm.

10.1049/el:20071583 article EN Electronics Letters 2007-09-12

Codman's paradox reveals a misunderstanding of geometry in orthopedic practice. Physicians often encounter situations that cannot be understood intuitively during interventions such as corrective osteotomy. Occasionally, unexpected angular or rotational deformity occurs surgery. This study aimed to draw the attention surgeons toward concepts orientation and rotation demonstrate potential for after interventions. focused on three situations: shoulder arthrodesis, femoral varization...

10.1186/1471-2474-15-175 article EN cc-by BMC Musculoskeletal Disorders 2014-05-24

Genotype of E. coli strains and plasmids

10.1016/s0021-9258(20)80687-5 article EN cc-by Journal of Biological Chemistry 1993-09-01

The factors that predict prostate cancer detection on repeat biopsy were evaluated in patients with atypical small acinar proliferation (ASAP) the initial biopsy.From 2003 to 2008, 3,130 men suspected underwent a needle biopsy, and 244 (7.8%) diagnosed as having ASAP. One hundred seventy of rebiopsied at least once more. They classified into group noncancer according final pathological diagnosis. database included age, prostate-specific antigen (PSA), PSA density (PSAD), velocity (PSAV),...

10.4111/kju.2010.51.11.752 article EN Korean journal of urology 2010-01-01
Coming Soon ...