A5102972121- Osteoarthritis Treatment and Mechanisms
- Mesenchymal stem cell research
- Tracheal and airway disorders
- Electrospun Nanofibers in Biomedical Applications
- Tissue Engineering and Regenerative Medicine
- Spinal Cord Injury Research
- Knee injuries and reconstruction techniques
- Intestinal and Peritoneal Adhesions
- Pancreatic function and diabetes
- 3D Printing in Biomedical Research
- Hernia repair and management
- Head and Neck Surgical Oncology
- Congenital Diaphragmatic Hernia Studies
- Bone Tissue Engineering Materials
- Esophageal and GI Pathology
- Veterinary Orthopedics and Neurology
- Diabetes Management and Research
- Veterinary Oncology Research
- Veterinary Medicine and Surgery
- IgG4-Related and Inflammatory Diseases
- Vascular Anomalies and Treatments
- Spinal Hematomas and Complications
- Bone Metabolism and Diseases
- Cutaneous lymphoproliferative disorders research
- Dendrimers and Hyperbranched Polymers
Konkuk University
2011-2016
Konkuk University Medical Center
2006
We induced percutaneous spinal cord injuries (SCI) using a balloon catheter in 45 rats and transplanted human umbilical blood derived mesenchymal stem cells (hUCB-MSCs) at the injury site.Locomotor function was significantly improved hUCB-MSCs groups.Quantitative ELISA of extract from entire injured showed increased expression brain-derived neurotrophic factor (BDNF), nerve growth (NGF) neurotrophin-3 (NT-3).Our results show that treatment SCI with can improve locomotor functions, suggest...
The use of human umbilical cord blood-derived mesenchymal stem cells for cell transplantation therapy holds great promise repairing spinal injury.Here we report the first clinical trial (hUCB)-derived (MSCs) into a dog suspected to have fibrocartilaginous embolic myelopathy (FCEM) and that experienced loss deep pain sensation.Locomotor functions improved following in dog.Based on our findings, suggest hUCB-derived MSCs will beneficial therapeutic effects FCEM patients lacking sensation.
Here, percutaneous spinal cord injury (SCI) methods using a balloon catheter in adult rats are described. A was inserted into the epidural space through lumbosacral junction and then inflated between T9-T10 for 10 min under fluoroscopic guidance. Animals were divided three groups with respect to inflation volume: 20 μL (n = 18), 50 18) control (Fogarty but not inflated; n 10). Neurological assessments made based on BBB score, magnetic resonance imaging histopathology. Both volumes produced...