A5022409275- Pluripotent Stem Cells Research
- Extracellular vesicles in disease
- Graphene and Nanomaterials Applications
- Nanoparticles: synthesis and applications
- Mesenchymal stem cell research
- MicroRNA in disease regulation
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Urological Disorders and Treatments
- RNA Research and Splicing
- Phytochemicals and Antioxidant Activities
- Cancer Cells and Metastasis
- Genomics, phytochemicals, and oxidative stress
- Urinary Bladder and Prostate Research
- Carbon and Quantum Dots Applications
- Pancreatic function and diabetes
- Salivary Gland Disorders and Functions
- Advanced Nanomaterials in Catalysis
- RNA modifications and cancer
- Circular RNAs in diseases
- Neurogenesis and neuroplasticity mechanisms
- Fibroblast Growth Factor Research
- Histone Deacetylase Inhibitors Research
- Periodontal Regeneration and Treatments
- Corneal Surgery and Treatments
Konkuk University
2016-2025
Konkuk University Medical Center
2012-2014
Background: Graphene holds great promise for potential use in next-generation electronic and photonic devices due to its unique high carrier mobility, good optical transparency, large surface area, biocompatibility. The aim of this study was investigate the antibacterial effects graphene oxide (GO) reduced (rGO) Pseudomonas aeruginosa . In work, we used a novel reducing agent, betamercaptoethanol (BME), synthesis avoid toxic materials. To uncover impacts GO rGO on human health, activity two...
The term ''oxidative stress" refers to a cell's state characterized by excessive production of reactive oxygen species (ROS) and oxidative stress is one the most important regulatory mechanisms for stem, cancer, cancer stem cells. concept cells arose from observations similarities between self-renewal mechanism that cells, but compared normal they are believed have no control over cell number. ROS been implicated in diverse processes various cancers, generally increase known play an role...
Influenza is an infectious respiratory disease with frequent seasonal epidemics that causes a high rate of mortality and morbidity in humans, poultry, animals. serious economic concern due to the costly countermeasures it necessitates. In this study, we compared antiviral activities several flavonols other flavonoids similar, but distinct, hydroxyl or methyl substitution patterns at 3, 3', 4' positions 15-carbon flavonoid skeleton, found strongest effect was induced by isorhamnetin. Similar...
The unexpected pandemic set off by the novel coronavirus 2019 (COVID-19) has caused severe panic among people worldwide. COVID-19 created havoc, and scientists physicians are urged to test efficiency safety of drugs used treat this disease. In such a situation, various steps have been taken government control prevent Severe Acute Respiratory Syndrome 2 (SARSCoV- 2). This situation forced rework strategies combat infectious diseases through drugs, treatment, measures. treatment requires both...
Studies have reported that interactions between keratins (KRTs) and other proteins initiate signaling cascades regulate cell migration, invasion, metastasis. In the current study, we found expression of KRT19 was specifically high in breast cancers significantly correlated with their invasiveness. Moreover, knockdown led to increased proliferation, drug resistance, sphere formation cancer cells via an upregulated NOTCH pathway. This owing reduced NUMB, inhibitory protein addition, interacts...
Epithelial-mesenchymal transition (EMT) occurs in the tumor microenvironment and presents an important mechanism of cell intravasation, stemness acquisition, metastasis. During metastasis, cells enter circulation to gain access distant tissues, but how this fluid influences cancer biology is poorly understood. Here, we present both vivo vitro evidence that EMT-like also circulating (CTCs) as a result hydrodynamic shear stress (+SS), which promotes conversion...
Kaavya Jayaramayya, Iyer Mahalaxmi, Mohana Devi Subramaniam, Neethu Raj, Ahmed Abdal Dayem, Kyung Min Lim, Se Jong Kim, Yub An, Yoonjoo Lee, Yujin Choi, Arthi Kirubhakaran, Ssang-Goo Cho & Balachandar Vellingiri. BMB Reports 2020;53:400-12. https://doi.org/10.5483/BMBRep.2020.53.8.121
Due to unique properties and unlimited possible applications, graphene has attracted abundant interest in the areas of nanobiotechnology. Recently, much work focused on synthesis graphene. Here we show that a successful reduction oxide (GO) using spinach leaf extract (SLE) as simultaneous reducing stabilizing agent. The as-prepared SLE-reduced (S-rGO) was characterized by ultraviolet-visible spectroscopy Fourier transform infrared spectroscopy. Dynamic light scattering technique used...
Abstract Nano‐scale materials are noted for unique properties, distinct from those of their bulk material equivalents. In this study, we prepared spherical silver nanoparticles (AgNPs) with an average size about 30 nm and tested potency to induce neuronal differentiation SH‐SY5Y cells. Human neuroblastoma cells considered ideal in vitro model studying neurogenesis, as they can be maintained undifferentiated state or induced differentiate into neuron‐like phenotypes by several...