A5052711621- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Pain Mechanisms and Treatments
- Orthopaedic implants and arthroplasty
- Biochemical effects in animals
- Stress Responses and Cortisol
- Neuroendocrine regulation and behavior
- Neuropeptides and Animal Physiology
- Temporomandibular Joint Disorders
- Facial Trauma and Fracture Management
- Cerebrovascular and genetic disorders
- Digital Imaging in Medicine
- Ion Channels and Receptors
- Voice and Speech Disorders
- dental development and anomalies
- Hemispheric Asymmetry in Neuroscience
- Rheumatoid Arthritis Research and Therapies
- Bone and Dental Protein Studies
- Cleft Lip and Palate Research
- Transplantation: Methods and Outcomes
- Dental Research and COVID-19
- Connective tissue disorders research
- Acupuncture Treatment Research Studies
- Bone health and treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
Niigata University Medical and Dental Hospital
2005-2025
Niigata University
1998-2025
Tokai University
2017
Okayama University
2013
The detailed mechanism of osseointegration, the most appropriate implant-bone interface, remains unclear in jaw tissues at ultrastructural level contrast to many reports using long bones. present study on tissue response titanium-implantation an animal model rat maxilla.Animals were sacrificed 1 28 days post-implantation and prepared specimens, freed from implants by a cryofracture technique, processed for transmission electron microscopy histochemistry tartrate resistant acid phosphatase...
T he present study aimed to establish a titanium implantation model using rat maxillae as well demonstrate the chronological tissue responses implantation. Pure implants were inserted, in upper first molar extraction sites of Wistar rats 1 month after tooth extraction. The animals sacrificed at 30 days postimplantation, and prepared specimens processed for light microscopy. removal from blocks was done 2 methods: mechanical or cryofracture technique. In early stages, peri‐implant tissues...
This study examined the effects of treadmill running (TR) regimens on craniofacial pain- and anxiety-like behaviors, as well their neural changes in specific brain regions male mice subjected to repeated social defeat stress (SDS) for 10 days. Behavioral immunohistochemical experiments were conducted evaluate impact TR SDS-related those epigenetic activity markers anterior cingulate cortex (ACC), insular (IC), rostral ventromedial medulla (RVM), cervical spinal dorsal horn (C2). responses...
Abstract Osseointegration is regarded as the most appropriate implant‐bone interface in dental implantation. However, damaged bone with empty osteocytic lacunae driven by implant cavity preparation remains even after completion of osseointegration. Although previous studies have suggested occurrence remodeling around implants, information on its detailed process meager. Our study aimed to examine fate titanium implants establishment osseointegration an animal model using rat maxilla....
Abstract: Tissue responses to titanium implantation with two different surface conditions in our established model rat maxillae were investigated by light and transmission electron microscopy histochemistry for tartrate‐resistant acid phosphatase (TRAPase) activity. Here we used types of implants qualities: sandblasted Al 2 O 3 (SA‐group) coated hydroxyapatite (HA‐group). In both groups, bone formation had begun 5 days postimplantation when the inflammatory reaction almost disappeared...
Background: Guided bone regeneration (GBR) has been widely utilized for the promotion of augmentation in loss areas. However, little information available regarding chronological changes newly formed and alterations nature after removal a barrier membrane. The present study attempted to establish GBR model rat maxillae. We also examined effects membrane application periods on its remodeling process this experimental model. Methods: Thirty‐five Wistar rats were divided into 2 groups: group...
Corneal cool cells are sensitive to the ocular fluid status of corneal surface and may be responsible for regulation basal tear production. Previously, we have shown that dry eye, induced by lacrimal gland excision (LGE) in rats, sensitized transient receptor potential melastatin 8 (TRPM8) agonist menthol stimulation. In present study, examined effect eye on sensitivity vanilloid 1 (TRPV1) capsaicin. Single-unit recordings trigeminal ganglion were performed 7–10 days after LGE. At a...
Abstract: The response of nerve fibres in the peri‐implant epithelium to titanium implantation was investigated with an experimental model using rat maxilla and immunohistochemical techniques. latter employed antibodies protein gene product 9.5 (PGP9.5), calcitonin gene‐related peptide (CGRP). In control rats without implantation, a dense innervation PGP9.5‐ CGRP‐positive recognized throughout junctional epithelium, as has been previously reported. A titanium‐implantation induced remarkable...
Abstract We investigated the effects of social defeat stress (SDS) and treadmill running on masseter muscle nociception, which was quantified by orofacial formalin test c‐Fos FosB immunoreactivities in upper cervical spinal cord (C1/C2) region male mice. After daily SDS or non‐SDS conditioning for 10 days, SDS‐conditioned mice were categorized into SDS‐susceptible versus resilient Several mice, including non‐SDS‐conditioned, SDS‐susceptible, selected to assess nociception Day 11. days...
Abstract The conditions of stress contagion are induced in bystanders without direct experiences stressful events. This study determined the effects on masseter muscle nociception mice. Stress was developed after cohabitating with a conspecific mouse subjected to social defeat for 10 days. On Day 11, increased anxiety‐ and orofacial inflammatory pain‐like behaviors. c‐Fos FosB immunoreactivities evoked by stimulation were upper cervical spinal cord, while expressions rostral ventromedial...
We developed a novel device that simultaneously measures oral and intrapharyngeal baropressure. The transducer has the advantage it can be placed in any region. determined effect of different speech samples on baropressure these regions.Seven healthy individuals produced comprising vowels consonants (e.g., /aka/, /apa/, /ash/). Two transducers were installed into experimental plate at incisive papillae center Ah-line; third was mid-pharyngeal cavity. During each task, 3 parameters analyzed:...
目的：従来，全部鋳造冠の支台歯形成についてさまざまな教育方法や評価方法が試みられてきたが，動画教材を用いて教育効果を検討したものや支台歯の客観的評価に関する報告は数少ないように思われる．そこで，本研究は効果的な教材と妥当性のある支台歯の評価方法の開発を目的として行った．方法：術者の視界を録画することができるように位置を調整したカメラを用いて記録した，動画教材を用意した．10名の研修歯科医がこの動画教材を視聴する前と後に行った支台歯形成の結果を，面積計算を用いたテーパーに関する客観的手法と上級医の主観的評価によって比較することにより，本教材の効果を検証した．さらに客観的評価と主観的評価の一致率についても検討を行った．結果：動画視聴後にはすべての支台歯において主観的評価が上がっており，支台歯のテーパー，形態については動画視聴前後で有意差が認められた．客観的評価には有意差が認められなかったが，主観的評価と強い相関を示していることがわかった．結論：今回開発した動画教材は支台歯形成の教育に効果的であることがわかった．さらに，支台歯のテーパーを客観的に評価する際には面積計算が有用であること，...
Aims: Dental procedures involve intricate techniques that can be challenging to visualize, often hindering imitation and assessment. In this study, the impression-taking performance of abutment teeth was quantitatively analyzed create objective indexes for dental skill education. Methods: Participants were divided into two groups different clinical experience levels: 10 dentists students. An aluminum model employed simplify experiment. optical motion capture system (VICON, Oxford, UK)...
症例の概要：患者は51歳の女性で下顎左側大臼歯部と上顎両側中切歯，上顎右側側切歯が欠損しており，明確なアンテリアガイダンス，咬合支持を失っていた．そこで，まず咬合支持の改善を優先的に行った後，プロビジョナルレストレーションを利用してアンテリアガイダンスを再構築した．考察：はじめに咬合支持の確立を行ったことにより，臼歯離開咬合を確実に付与することができた．結論：アンテリアガイダンスの修復が求められる症例においては，臼歯部での咬合支持を確立した後にプロビジョナルレストレーションを用いて適切なガイドを模索し，カスタムインサイザルテーブルによって最終補綴装置に反映させる方法が効果的である．