A5058810370- Mass Spectrometry Techniques and Applications
- Hydrocarbon exploration and reservoir analysis
- Petroleum Processing and Analysis
- Microbial Natural Products and Biosynthesis
- Plant biochemistry and biosynthesis
- Analytical chemistry methods development
- Pesticide Residue Analysis and Safety
- Cholinesterase and Neurodegenerative Diseases
- Liver Disease Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
- Drilling and Well Engineering
- Fungal Biology and Applications
- Diet, Metabolism, and Disease
- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Luminescence and Fluorescent Materials
- Computational Drug Discovery Methods
- Synthesis and biological activity
- Chemical synthesis and alkaloids
- Analytical Chemistry and Chromatography
- Plant Pathogens and Fungal Diseases
- Photochromic and Fluorescence Chemistry
- Plant and fungal interactions
- Multicomponent Synthesis of Heterocycles
- Bioactive Natural Diterpenoids Research
Universidade Federal de Goiás
2019-2025
Grupo Hospitalar Conceição
2024
Universidade Federal do Pará
2024
Universidade Estadual de Ponta Grossa
2024
Universidade Federal de Minas Gerais
2014-2021
Pontifical Catholic University of Peru
2020
Universidade de São Paulo
2019
Universidad de Cádiz
2017
Universidade Estadual Paulista (Unesp)
2015
Centro Universitário de Belo Horizonte
2014
COVID-19 is characterized by diverse clinical outcomes that include asymptomatic to mild manifestations or severe disease and death. Infection SARS-CoV-2 activates inflammatory metabolic responses drive protection pathology.
In this study, we introduce a pioneering approach that leverages advanced machine learning and ultrahigh-resolution Fourier transform ion cyclotron mass spectrometry (FT-ICR MS) data to predict the distribution of total acid number (TAN) in true boiling point (TBP) distillation cuts from crude oil. By employing partial least-squares (PLS) regression ordered predictor selection (OPS), achieved robust predictive models with high accuracy, evidenced by low root-mean-square error calibration...
Abstract Objectives To evaluate whether the glycosylation of chrysin (CHR) enhances its protective effects against aluminum-induced neurotoxicity. Methods compare antioxidant, anticholinesterase, and behavioral CHR with glycosylated form (CHR bonded to β-d-glucose tetraacetate, denoted as LQFM280), we employed an integrated approach using both in vitro (SH-SY5Y cells) vivo (aluminum-induced neurotoxicity Swiss mice) models. Key findings LQFM280 demonstrated higher antioxidant activity than...
Naphthenic acids comprise one of the most toxic compounds produced water released from offshore oil platforms. Therefore, developing and applying faster, simpler, more efficient analytical methods for analyzing naphthenic are urgently needed. Electromembrane extraction (EME) uses electrokinetic migration target ions through a porous membrane. Herein, EME method was applied to extract water. The optimized, optimal conditions encompassed decanol as organic solvent, sample with pH 10.0, 5 min...
Background: The study evaluated the influence of whitening dentifrice containing activated charcoal on microhardness (MH), surface roughness (Ra) and colorimetry tooth enamel.Material Methods: A total 60 healthy bovine incisor teeth were used divided into: G1 (regular non-whitening toothpaste), G2 (conventional G3 (activated based toothpaste) G4 (10% carbamide peroxide gel -PC10).Groups G1, underwent simulated toothbrushing for 14 days, while received bleaching treatment same time.The...
Potato (Solanum tuberosum L.) is one of the world's most important crops, but it facing major challenges due to climatic changes. To investigate effects intermittent drought on natural variability plant morphology and tuber metabolism in a novel potato association panel comprising 258 varieties we performed an augmented block design field study under normal irrigation water-deficit recovery conditions Ica, Peru. All genotypes were profiled for 45 morphological traits 42 central metabolites...
Abstract This work describes a simple and efficient alternative method for obtaining 1,3,4‐thiadialzolinic spirocompounds, combining the use of deep eutectic solvents (DES) with microwave irradiation in one‐pot process. A series DES based on different acids was explored as solvent three‐component reaction including isatin derivatives (monomeric dimeric), thiosemicarbazide, acetic anhydride. Choline chloride oxalic acid (1:1) showed better results concerning other evaluated, reaching yields...
The liquid chromatography-mass spectrometry (LC-MS)-based metabolomics approach is a powerful technology for discovering novel biologically active molecules. In this study, we investigated the metabolic profiling of Orchidaceae species using LC-HRMS/MS data combined with chemometric methods and dereplication tools to discover antifungal compounds. We analyze twenty ethanolic plant extracts from Vanda Cattleya (Orchidaceae) genera. Molecular networking were used discriminate ions that...
Employing a combination of liquid chromatography electrospray ionization and paper spray high-resolution tandem mass spectrometry, extracts from cupuassu (Theobroma grandiflorum) pulp prepared with either water, methanol, acetonitrile or combinations thereof were subjected to metabolite fingerprinting. Among the tested extractors, 100% methanol extracted preferentially phenols cinnamic acids derivatives, whereas acetonitrile/methanol more effective in extracting terpenoids flavonoids,...
A doença hepática gordurosa não alcoólica (DHGNA) é altamente prevalente e seus portadores possuem risco aumentado de desenvolver doenças cardiovasculares, inclusive a hipertensão arterial sistêmica (HAS). prevalência HAS nesses pacientes estimada em 39,34%, entretanto, há critérios escolha anti-hipertensivos nesse contexto. 34 coelhos foram divididos grupo olmesartana (GO) n=12, controle (GC) n=13, normal (GCN) n=9. O GCN recebeu ração padrão os GC GO acrescida colesterol 1%. via oral,...
Produced water, a complex saline concoction, houses naphthenic acids (NAs), some of the most potent organic toxins that significantly threaten aquatic life. Deciphering molecular intricacy NAs is formidable task as result their composite nature comprising numerous isomers are hard to distinguish and characterize. While substantial research has examined in oil sand process-affected there dearth studies regarding characterization produced water from offshore platforms. Consequently, for an...