A5101540765- Protein Structure and Dynamics
- Enzyme Structure and Function
- Communication and COVID-19 Impact
- Advanced Chemical Sensor Technologies
- Metabolomics and Mass Spectrometry Studies
- Plant biochemistry and biosynthesis
- Advanced NMR Techniques and Applications
- Spectroscopy and Chemometric Analyses
- Environmental and sustainability education
- Phytochemicals and Medicinal Plants
- Biochemical and biochemical processes
- Plant Pathogens and Resistance
- Mass Spectrometry Techniques and Applications
- Journalism and Media Studies
- Public Policy and Governance
- Cultural and political discourse analysis
- Traditional Chinese Medicine Studies
- GABA and Rice Research
- Plant Stress Responses and Tolerance
- Potato Plant Research
- Plant Disease Resistance and Genetics
The Ohio State University
2022-2024
Pontifical Catholic University of Peru
2000-2021
Abstract Even though Pure Shift NMR methods have conveniently been used in the assessment of crowded spectra, they are not commonly applied to analysis metabolomics data. This paper exploits recently published SAPPHIRE-PSYCHE methodology context plant metabolome. We compare single pulse, PSYCHE, and spectra obtained from aqueous extracts Physalis peruviana fruits. STOCSY with simplified six types Cape gooseberry was carried out results attained compared classical PLS coefficients combined...
Potato (Solanum tuberosum L.) is one of the world's most important crops, but it facing major challenges due to climatic changes. To investigate effects intermittent drought on natural variability plant morphology and tuber metabolism in a novel potato association panel comprising 258 varieties we performed an augmented block design field study under normal irrigation water-deficit recovery conditions Ica, Peru. All genotypes were profiled for 45 morphological traits 42 central metabolites...
An NMR NOAH-supersequence is presented consisting of five CEST experiments for studying protein backbone and side-chain dynamics by 15N-CEST, carbonyl-13CO-CEST, aromatic-13Car-CEST, 13Cα-CEST, methyl-13Cmet-CEST. The new sequence acquires the data these in a fraction time required individual experiments, saving over four days per sample.
An NMR supersequence is introduced for the rapid acquisition of 15N-CEST and methyl-13C-CEST experiments in same pulse sequence applications to proteins. The high sensitivity accuracy allows simultaneous quantitative characterization backbone side-chain dynamics on millisecond timescale ideal routine screening alternative protein states.
The field of metabolomics, which is quintessential in today's omics research, involves the large-scale detection, identification, and quantification small-molecule metabolites a wide range biological samples. Nuclear magnetic resonance spectroscopy (NMR) has emerged as powerful tool for metabolomics due to its high resolution, reproducibility, exceptional quantitative nature. One key bottlenecks studies, however, remains accurate automated analysis resulting NMR spectra with good accuracy...