A5004388078- Vasculitis and related conditions
- Urticaria and Related Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Chemotherapy-induced cardiotoxicity and mitigation
- Nanoparticle-Based Drug Delivery
- Leptospirosis research and findings
- Renal Diseases and Glomerulopathies
- Vascular Anomalies and Treatments
- Otitis Media and Relapsing Polychondritis
- Advanced Drug Delivery Systems
- Chronic Myeloid Leukemia Treatments
- Genetic and Kidney Cyst Diseases
- Polymer Surface Interaction Studies
Beaumont Hospital
2020-2022
Royal College of Surgeons in Ireland
2016-2019
Nanotechnology is being increasingly utilised in medicine as diagnostics and for drug delivery targeting. The small size high surface area of nanoparticles (NPs), desirable properties that allow them to cross biological barriers, also offer potential interaction with other cells blood constituents, presenting possible safety risks. While NPs investigated are predominantly based on the biodegradable, biocompatible, FDA approved poly-lactide-co-glycolide (PLGA) polymers, pro-aggregatory...
Purpose of the Study. Antineutrophil cytoplasmic antibody- (ANCA-) associated vasculitis (AAV) is a rare multisystem autoimmune condition with an incidence 0.4–24 per 1 million person- years. The severity renal involvement predicts prognosis. Limited data are available on its management and outcomes; thus, we aim to assess this at our tertiary-care facility. Study Design. Retrospective were collected using national electronic database (eMED) identify AAV patients over period 6 Outcomes...
Leptospirosis is an exceptionally rare infectious disease in the Republic of Ireland. can present with or mimic thrombotic microangiopathies (TTP/HUS). A 48-year-old male presented to a peripheral hospital short history diarrhoea, anaemia, hyperbilirubinemia, raised lactate dehydrogenase, thrombocytopenia, and severe acute kidney injury was transferred our tertiary care centre. form microangiopathy (TMA) suspected. However, no schistocytes were seen on blood film, reticulocyte count...
Anti neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV) is a rare disorder with annual incidence estimated to be around 1.3 per 100,000 population. Renal involvement one of the main predictors mortality and morbidity, approximately 30% patients renal progressing ESRD after 5 years. biopsy can provide definite diagnosis, may predict prognosis in AAV. Limited data available on its management outcomes, thus we aim assess this at our tertiary care facility.
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