A5017858528- Traditional Chinese Medicine Studies
- Medical Research and Treatments
- Sperm and Testicular Function
- Healthcare and Venom Research
- Inflammasome and immune disorders
- Educational Reforms and Innovations
- Hormonal and reproductive studies
- Cancer, Lipids, and Metabolism
- Mitochondrial Function and Pathology
- Neurological Disorders and Treatments
- IgG4-Related and Inflammatory Diseases
- Brain Tumor Detection and Classification
- Gout, Hyperuricemia, Uric Acid
- Polysaccharides and Plant Cell Walls
- Molecular Biology Techniques and Applications
- Circular RNAs in diseases
- Rheumatoid Arthritis Research and Therapies
- Traditional Chinese Medicine Analysis
- Intracerebral and Subarachnoid Hemorrhage Research
- Genomics, phytochemicals, and oxidative stress
- Phytochemical Studies and Bioactivities
- Natural Products and Biological Research
- Cancer, Hypoxia, and Metabolism
- AI in cancer detection
- Craniofacial Disorders and Treatments
Hunan University
2011-2025
Hunan University of Traditional Chinese Medicine
2006-2024
Integrated Chinese Medicine (China)
2020-2024
Huaihua University
2023
First Affiliated Hospital of Hunan University of Traditional Chinese Medicine
2010-2022
University of California System
2014
Changchun University of Chinese Medicine
2011
Context The risk of contrast-induced acute kidney injury (CI-AKI) is increasing and the harm great. Quercetin main active component in Abelmoschus manihot (L.) Medik (Malvaceae) was reported to reduce expression HIF-1α.Objective We investigate whether quercetin improves CI-AKI through HIF-1α/lncRNA NEAT1/HMGB1 pathway.Materials methods HK-2 cells were treated with iohexol (200 mg/mL) for 6 h establish a model. (20 μM) administered cultured dishes 24 h. Cell morphology observed by...
Prostate cancer (PCa) ranks as the second most common disease among men and fourth prevalent worldwide. Enhanced glycolysis excessive lactate secretion are recognized critical factors driving progression of various cancers. This study systematically investigated research trends associated with in PCa through bibliometric analysis. In this study, we conducted a systematic search Web Science PubMed databases for literature pertaining to that was published between January 1, 2004, June 30,...
Polygonatum sibiricum polysaccharides (PSP), the primary constituent of sibiricum, have been shown to exhibit a wide range pharmacological effects, but their impact on osteoarthritis (OA) remains unclear. The objective this study was investigate protective effects PSP against OA and elucidate its underlying molecular mechanism. In our in vitro experiments, not only inhibited IL-1β-induced inflammatory responses nuclear factor kappa-B (NF-κB) signaling pathway chondrocytes also regulated...
Brain Tumor originates from abnormal cells, which is developed uncontrollably. Magnetic resonance imaging (MRI) to generate high-quality images and provide extensive medical research information. The machine learning algorithms can improve the diagnostic value of MRI obtain automation accurate classification MRI. In this research, we propose a supervised applied training testing model classify analyze features brain tumors in performance accuracy, precision, sensitivity F1 score. result...
Background Male infertility is a worldwide population health concern, but its etiology remains poorly understood. Tortoise-shell glue (TSG) widely utilized as pharmaceutical or dietary supplement for various ailments. This study aimed to evaluate the effects of TSG on male in obese rats.
Background: Platycodin D (PLD) comes from the main triterpenoid saponins in dry roots of Platycodon grandiflorum, which has been used traditional Chinese medicine treatment respiratory disease. This study aimed to evaluate therapeutic effects PLD on mouse alveolar macrophages induced by influenza A virus (IAV) vitro and investigate its action. Materials Methods: Raw264.7 were grown culture Cell Counting Kit-8 assay determined cell viability. Cells treated for 24 h with increasing doses (0,...
This study aims to explore the effect of Buyang Huanwu Decoction glycosides on inflammatory response apolipoprotein E~(-/-)(ApoE~(-/-)) mice and RAW264.7 cells through nuclear factor kappa-B(NF-κB) signaling pathway. In in vivo experiment, ApoE~(-/-) were fed with high-fat diets for 12 weeks induce animal model atherosclerosis, 75 μg·mL~(-1) oxidized low-density lipoprotein(Ox-LDL) incubated 24 h establish atherosclerosis cell model. Automatic biochemical analyzer, hematoxylin-eosin(HE)...
This study aimed to examine and propagate the medication experience group formula of traditional Chinese medicine (TCM) Master XIONG Jibo in diagnosing treating arthralgia syndrome (AS) through data mining. Data outpatient cases Professor were collected from January 1, 2014 December 31, 2018, along with recorded A Real Famous Traditional Medicine Doctor: Jibo's Clinical Medical Record which was published 2019. The five variables patients' TCM diagnostic information, western diagnoses,...
The progression of diabetic nephropathy (DN) is closely associated with lipid accumulation. Diosgenin (Dio) plays a beneficial role in the metabolism multiple diseases. Thus, mechanism underlying Dio's function DN aberrant accumulation warrants further investigation.
This study aims to explore the influence of Polygonati Rhizoma on pyroptosis in rat model diabetic macroangiopathy via NOD-like receptor thermal protein domain associated 3(NLRP3)/cysteinyl aspartate specific proteinase-1(caspase-1)/gasdermin D(GSDMD) pathway. The diabetes was established by intraperitoneal injection streptozotocin(STZ) combined with a high-fat, high-sugar diet. blood glucose meter, fully automated biochemical analyzer, hematoxylin-eosin(HE) staining, enzyme-linked...