Alexandra D. Stroeva

ORCID: 0000-0002-4179-931X
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About
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Research Areas
  • Herpesvirus Infections and Treatments
  • Virus-based gene therapy research
  • Virology and Viral Diseases
  • Animal Virus Infections Studies
  • Pharmacological Effects of Natural Compounds
  • Influenza Virus Research Studies
  • Poxvirus research and outbreaks
  • Respiratory viral infections research
  • Immune responses and vaccinations
  • Pediatric health and respiratory diseases
  • SARS-CoV-2 and COVID-19 Research
  • Cytokine Signaling Pathways and Interactions
  • Viral gastroenteritis research and epidemiology

Research Institute of Vaccines and Sera. Mechnikov of the Russian Academy of Medical Sciences
2020-2023

Introduction. The antigen complex of opportunistic pathogenic bacteria (ACOPB) has a protective effect against avian influenza viruses, herpes virus type 2, and other viruses that cause acute respiratory viral infections. In the context COVID-19 pandemic, an important task is to find out whether ACOPB SARS-CoV-2.
 purpose study was evaluate in vitro virus-inhibitory activity Dubrovka laboratory strain Materials methods. performed using Vero cell line CCL-81, human peripheral blood...

10.36233/0372-9311-309 article EN cc-by Journal of microbiology epidemiology immunobiology 2023-05-22

Until now, it has been considered that infectivity of the varicella-zoster virus (VZV) is closely related to target cell, and newly formed not released into culture medium. It also known hard grow VZV in cell cultures, due its slow replication rate a limited range sensitive cultures. In addition, isolation depends on type used, nature clinical material, presence viable transport time. Objectives. To study production infectious extracellular various Materials methods. Eight cultures were...

10.15789/2220-7619-pao-1211 article EN cc-by Russian Journal of Infection and Immunity 2020-04-09

Introduction. Chickenpox poses a significant public health concern due to its worldwide occurrence, substantial probability of severe clinical progression, development complications that can lead fatal outcome. Routine vaccination is the only way prevent disease. The purpose this study was assess attenuation cold-adapted (CA) candidate virus strains Varicella zoster and Herpes by using traditional new methods.Materials methods. performed on diploid cells from human embryonic lung...

10.36233/0372-9311-2020-97-4-2 article EN cc-by Journal of microbiology epidemiology immunobiology 2020-09-02

Purpose: characterization of vFiraVax (the causative agent chickenpox - VZV) and vZelVax shingles HZ) vaccine strains by their ability to bind preparations brain membrane receptors SPF BALB/c mice.Materials Methods. The study was performed on cold-adapted VZV HZ developed the authors basis wild-type parental pFira virus (chickenpox agent) latent lpZel (shingles agent); vOka isolated from vaccines against infection two manufactures (United Kingdom USA); HEL-3 strain diploid cells human...

10.36233/0372-9311-2020-97-2-125-133 article EN cc-by Journal of microbiology epidemiology immunobiology 2020-05-06

Журнал для непрерывного медицинского образования врачей Новый подход к оценке иммуномодулирующей и вирус-ингибирующей активности медицинских препаратов ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ1 Федеральное государственное бюджетное научное учреждение «Научноисследовательский институт вакцин сывороток имени И.И.

10.33029/2305-3496-2022-11-4-82-90 article RU Infectious diseases News Opinions Training 2022-01-01

Introduction. Rubella is a mild infectious disease affecting mainly children and caused by the rubella virus, part of Matonoviridae family, genus Rubivirus. causes congenital syndrome (CRS) main cause developmental abnormalities, especially blindness deafness.
 There no specific treatment for CRS. In order to avoid possible complications from infection, live attenuated vaccine based on foreign strain Wistar RA 27/3 virus used. However, actual, more effective preferred Russian Federation...

10.36233/0372-9311-320 article EN cc-by Journal of microbiology epidemiology immunobiology 2022-12-07
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