A5037856311- Epilepsy research and treatment
- Neurological disorders and treatments
- Glycogen Storage Diseases and Myoclonus
- Neuroscience and Neuropharmacology Research
- EEG and Brain-Computer Interfaces
- Pharmacological Effects and Toxicity Studies
- Sleep and Wakefulness Research
- Genetics and Neurodevelopmental Disorders
- Metabolism and Genetic Disorders
- Autoimmune Neurological Disorders and Treatments
- Transcranial Magnetic Stimulation Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Vestibular and auditory disorders
- Educational and Social Studies
- Fetal and Pediatric Neurological Disorders
- Diet and metabolism studies
- Sleep and related disorders
- Neonatal and fetal brain pathology
- Psychosomatic Disorders and Their Treatments
- Mitochondrial Function and Pathology
- Face Recognition and Perception
- Memory and Neural Mechanisms
- Neurological and metabolic disorders
- Neural dynamics and brain function
- Linguistic Studies and Language Acquisition
University of Bologna
2012-2024
University of Verona
1976-2024
Zambon (Italy)
2023
Ospedale Bellaria
2001-2019
Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
2018
Délégation Provence et Corse
2015
University of Parma
2010-2015
Institute of Neurological Sciences
1988-2014
Istituti di Ricovero e Cura a Carattere Scientifico
2002-2011
University of Modena and Reggio Emilia
2003-2008
INTRODUCTION PRINCIPLES FOR TERMS AND DEFINITIONS DATA SOURCES I GENERAL 1.0 SEMIOLOGY 2.0 EPILEPTIC SEIZURE 3.0 ICTUS 4.0 EPILEPSY 5.0 FOCAL 6.0 GENERALIZED 7.0 CONVULSION II DESCRIBING MOTOR 1.1 ELEMENTARY 1.1.1 TONIC 1.1.1.1 SPASM 1.1.1.2 POSTURAL 1.1.1.2.1 VERSIVE 1.1.1.2.2 DYSTONIC 1.1.2 MYOCLONIC 1.1.2.1 NEGATIVE 1.1.2.2 CLONIC 1.1.2.2.1 JACKSONIAN MARCH 1.1.3 TONIC-CLONIC 1.1.3.1 1.1.4 ATONIC 1.1.5 ASTATIC 1.1.6 SYNCHRONOUS 1.2 AUTOMATISM 1.2.1 OROALIMENTARY 1.2.2 MIMETIC 1.2.3 MANUAL...
RÉSUMÉ Les auteurs fournissent la description d'une variété très grave d‘épilepsie de l'enfant qui est rebelle à thérapeutique et se caractérise par triade symptomatique suivante: (1) crises épileptiques généralisées fréquentes, le plus souvent type toniques ou d'absences variantes petit mal; (2) déficit intellectuel grave; (3) décharges électroencéphalographiques intercritiques pointes‐ondes lentes diffuses répétées façon pseudo‐rythmique 1.5–2.5 c/s. Un pareil tableau diffère peu celui...
RÉSUMÉ Les auteurs distinguent trois variétés de crises épileptiques suivant leurs conditions d'apparition: A. fortuites B. cycliques 1. avec une périodicité latente; 2. distribution cyclique manifeste liée au cycle nyctohémérique ou à des facteurs hormonaux (cycle oestral, puberté, ménopause). C. provoquées Crises par déclenchants non‐sensoriels: (a) hyperthermie, (b) ingestion d'alcool, (c) hyperpnée, (d) désordres métaboliques, (e) fatique physique et privation sommeil, (f) émotions, (g)...
One hundred and ninety-two fragile X male patients were investigated for seizures EEG findings, 168 in a retrospective 24 another prospective study, to characterize the natural history of seizures, epilepsy, abnormalities males with this syndrome.Seizures documented 35 (18.2%) 192 patients; they never started before age 2 years or after 9 years. Seizures frequently complex partial type less motor generalized type. involving frontal temporal lobes commonly seen usually well controlled by...
<b><i>Background:</i></b> Anteromedial temporal lobe regions, particularly the amygdala, participate in recognition of emotions from facial expressions. The authors studied ability emotion (ER) subjects with symptomatic epilepsy, evaluating whether mesial damage is related to an impairment specific and onset seizures a critical period life could prevent development ER. <b><i>Methods:</i></b> Groups included patients epilepsy (TLE) MRI evidence sclerosis (MTS) (n = 33); TLE lesions other than...
In cats, the monosynaptic reflex (MSR) elicited from L7 or S1 dorsal roots, tibial nerve (H reflex) was suppressed by vibration at 50–500 c/s of hind limb with innervation intact. The MSR not selective cutaneous receptors, and suppression still observed after skinned. contrast, phenomenon disappeared when all muscle nerves were crushed. Suppression shown to be mediated presynaptic inhibition following methods: correlation onset root potential (DRP) evoked vibration, abolition both DRP...
Summary: Purpose : We wished to evaluate adjunctive therapy for partial‐onset seizures with topiramate (TPM) efficacy and safety in a double‐blind, placebo‐controlled, randomized, parallel‐group study. Methods Sixty outpatients epilepsy (47 men 13 women, mean age 32.9 years) were studied. All had documented history of or without secondarily generalized seizures. After an 8‐week baseline during which patients at least one seizure per week, 30 each randomized TPM 300 mg twice daily (b.i.d.)...
SUMMARY Valium has proved to be one of the most effective drugs we have used in treatment status epilepticus. We given or more injections intravenously intramuscularly, and also up 100 mg daily a slow intravenous drip. Most are stopped few seconds minutes, whether generalized partial, convulsive non‐convulsive. In doses met no respiratory nor cardiac side effects. is, our opinion, drug choice for emergency all cases Moreover it enables distinguish properly so‐called which stops cases, from...
SUMMARY Surface and depth EEG seizure patterns were compared in 34 patients with intractable temporal lobe epilepsy whom electrodes had been chronically implanted order to localize epileptogenic sites a view surgery. records accompanied by clinical seizures, auras, no behavioral changes, as well for which observations made, judged respect the manner activity originating unilaterally of one lobes spread surface. For each record, onset was classified being focal or regional form, as: (1) not...
SUMMARY Since 1965, 359 parenteral injections of benzodiazepines were performed during polygraphic control in 220 epileptic children. In 5 patients, who suffered with the syndrome Lennox‐Gastaut, i.v. injection a benzodiazepine (diazepam or Nitrazepam®) was followed immediately by numerous tonic seizures, both subclinical and clinical, amounting to true status. All patients one exception at time state confusion showed continuous discharges slow spike‐waves. had received other little effect,...
Summary ESES (encephalopathy with status epilepticus during sleep) is an epileptic encephalopathy heterogeneous clinical manifestations (cognitive, motor, and behavioral disturbances in different associations, various seizure types) related to a peculiar electroencephalography (EEG) pattern characterized by paroxysmal activity significantly activated slow sleep—that is, condition of continuous spikes waves, or epilepticus, sleep. The pathophysiologic mechanisms underlying this are still...
Subcortical band heterotopia (SBH) are bilateral and symmetric ribbons of gray matter found in the central white between cortex ventricular surface, which comprises less severe end lissencephaly (agyria-pachygyria-band) spectrum malformations. Mutations DCX (also known as XLS) have previously been described females with SBH. We now identified mutations either or LIS1 gene three 11 boys studied, demonstrating for first time that can cause SBH mixed pachygyria-SBH (PCH-SBH) males. All changes...
Thirty-one patients with severe drug-resistant epilepsy entered the study. Vigabatrin (2 to 3 g/d, stratified according weight) and placebo were administered orally, as add-on therapy in random order under double-blind conditions, each for three months using a crossover design. Thirty completed both periods. Of these, ten (33%) showed decrease seizure frequency of 50% or more. In 15 presenting complex partial seizures, "temporal" electroencephalographic abnormalities, relatively low...
Summary: Purpose: To describe the clinical and genetic findings of seven additional pedigrees with autosomal dominant lateral temporal epilepsy (ADLTE). Methods: A personal family history was obtained from each affected unaffected member, along a physical neurologic examination. Routine sleep EEGs, computed tomography (CT), or magnetic resonance imaging (MRI) were performed in almost all patients. DNAs members typed several microsatellite markers localized on either side LGI1 at 10q24...
SUMMARY Seven boys aged between 14 months and 13 years with focal or multifocal partial epilepsy had very unusual seizures, characterized by series of periodic bilateral spasms. These consisted a brief, complex movement slight to severe intensity, mainly involving the axial muscles, raising shoulders, adversion eyes head, often rictus‐type facial grimaces occasional stretching legs emission guttural sound. The ictal EEG showed pattern complexes, slow wave superimposed fast activity. This...