A5100326095- Nanoplatforms for cancer theranostics
- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Carbon and Quantum Dots Applications
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Nanocluster Synthesis and Applications
- Electrochemical sensors and biosensors
- Nuclear Materials and Properties
- Conducting polymers and applications
- Phytochemicals and Medicinal Plants
- Hydrogen embrittlement and corrosion behaviors in metals
- Graphene and Nanomaterials Applications
- Fluid Dynamics and Thin Films
- Analytical Chemistry and Sensors
- Organic Electronics and Photovoltaics
- Streptococcal Infections and Treatments
- Quantum Dots Synthesis And Properties
- Acute Kidney Injury Research
- Advanced Drug Delivery Systems
- Pickering emulsions and particle stabilization
- Hydrogels: synthesis, properties, applications
- Magnesium Alloys: Properties and Applications
Hangzhou Normal University
2019-2025
Nanjing Forestry University
2021-2024
Taiyuan University of Technology
2024
Sun Yat-sen University
2024
Xiyuan Hospital
2024
Third People's Hospital of Hefei
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
University of Science and Technology Beijing
2023
Central South University
2022-2023
National University Heart Centre Singapore
2021
Thin film fabrication is of great importance in modern engineering. Here, we propose a universal and conformal thin technique enabled by the wetting empowered interfacial self-assembly. By tailoring contact angle nanoparticle (NP), NP monolayer can be assembled instantly (within 5 seconds) with an excellent harvesting efficiency (up to 97.5 weight %). This self-assembly strategy presents applicability on various materials, e.g., nonmetal, metal, core-shell structures, achieve same in-plane...
Abstract Fluorescent probes capable of in vivo lipids labeling are highly desirable for studying lipid‐accumulation‐related metabolic diseases, such as nonalcoholic fatty liver disease, type‐2 diabetes, and atherosclerosis. However, most the current lipid‐specific fluorophores cannot be used due to their strong hydrophobicity. Herein, organic dots from bright luminogens with aggregation‐induced emission (AIEgen) developed three‐photon fluorescence imaging lipid‐rich tissues, liver,...
Most enzyme catalysts are unable to achieve effective oxidation resistance because of the monotonous mimicking function or production secondary reactive oxygen species (ROS). Herein, Au@Cu2O heterostructure with multienzyme-like activities is deigned, which has significantly improved antioxidant capacity compared pure Cu2O for scavenging highly cell-damaging ROS, i.e.,·OH. Experiments and theoretical calculations show that exhibits a built-in electric field lattice mismatch at...
Dual stimuli-responsive unimolecular micelles from “Y”-shape armed amphiphilic star-like copolymer are designed for controlled drug delivery.
In this report, a new star-like copolymer β-CD-g-(PNIPAAm-b-POEGA)x, consisting of β-CD core, grafted with temperature-responsive poly(N-isopropylacrylamide) (PNIPAAm) and biocompatible poly(oligo(ethylene glycol) acrylate) (POEGA) in block the arms, was used to deliver chemotherapeutics drug resistant cancer cells tumors. The first step self-assembly process involves encapsulation through host–guest inclusion complexation between β-cyclodextrin cavity anticancer drug. Next, chain...
Abstract Multi‐layered plasmonic nanostructures are able to highly promote the near‐field confinement and effectively activate analytes, which of predominate significance but extremely challenging. Herein, semi‐open Au core@carved AuAg multi‐shell superstructure nanoparticles (multi‐Au@Ag‐Au NPs, multi = mono, bi, tri, tetra, penta) reported with a high designability on electromagnetic field capability capturing analytes. By controlling synthetic parameters such as number galvanic exchange...
Designing and synthesizing multishelled metallic hollow nanostructures with intragaps porous shells have received widespread attention for enhancing optical catalytic properties. However, significant challenges remain in engineering these structures at the nanometer scale. Herein, we employed galvanic replacement reaction (GRR) method to prepare multimetallic superstructures 3D cavities distinct intragaps. By precise control of intragap distances (1–10 nm) composition distributions within a...
Abstract Pump mediated drug efflux is the key reason to result in failure of chemotherapy. Herein, a novel star polymer β‐CD‐ v ‐(PEG‐β‐PNIPAAm) 7 consisting β‐CD core, grafted with thermo‐responsive poly( N ‐isopropylacrylamide) (PNIPAAm) and biocompatible poly(ethylene glycol) (PEG) multiple “V”‐shaped arms designed further fabricated into supramolecular nanocarriers for resistant cancer therapy. The could encapsulate chemotherapeutics between β‐cyclodextrin anti‐cancer via inclusion...
Tacrolimus (FK506) is widely used in the prevention of organ transplant rejection and treatment autoimmune diseases, but it difficult to detect within low narrow concentration range practical clinical fields. A magnetic plasmonic superstructure-targets-plasmonic superstructure-based sandwich-type SERS biosensor presented here ultrasensitively FK506 blood patients. The spiky Fe3O4@SiO2@Ag flower superstructure hollow Ag@Au enhanced signals by providing rich sharp tips, cavities, abundant hot...
Cellulose is the most abundant natural polymer with good biodegradability and biocompatibility. In this paper, a novel fluorescent probe DAC-SD-NA for aluminum (Al3+ ) detection successfully synthesized based on dialdehyde cellulose (DAC). exhibited remarkable "turn-on" fluorescence response to Al3+ in wide pH range, color of solution turned from colorless bright blue at presence . The limit computed be 6.06×10-7 m. reaction mechanism towards confirmed by Job's plot, X-ray photoelectron...
A new A<sub>2</sub>–π–A<sub>1</sub>–π–A<sub>2</sub>-type small-molecule donor using a strong electron-withdrawing unit as the central was synthesized and its photovoltaic performance investigated.
The nanodrug delivery system-based nasal spray (NDDS-NS) can bypass the blood-brain barrier and deliver drugs directly to brain, offering unparalleled advantages in treatment of central nervous system (CNS) diseases. However, current design NNDS-NS is excessively focused on mucosal absorption while neglecting impact deposition nose-to-brain drug delivery, resulting an unsatisfactory efficiency. In this study, effect dispersion medium viscosity NDDS-NS was elucidated. optimized formulation F5...
Acoustic kinetic therapy systems that target specific organelles can improve the precision of a sonosensitizer, which is perfect combination targeted and sonodynamic (SDT) plays an important role in current acoustic therapy. In this study, we loaded PpIX, on targeted-functional carbon dots (CDs) via amide reaction then generated mitochondria-targeted system (Mit-CDs-PpIX) nucleus-targeted (Nuc-CDs-PpIX), respectively, to deliver sonosensitizer. Both exhibited minimal cytotoxicity absence...
Comprehensive Summary Plasmonic superlattices of nanoparticles (NPs) possess unique “surface lattice resonances” properties that facilitates their wide applications in plasmonic sensing, photocatalysis, and nanoscale light manipulation. However, it is still challenging to manufacture with precisely controllable NPs distance break the size limitation NPs. Herein, we provided an effective strategy construct via shape‐persistent polyhedral oligosilsesquioxane (POSS) molecular govern interfacial...
As an irreplaceable structural and functional material in strategic equipment, uranium alloys are generally susceptible to corrosion reactions during service, predicting behavior has important research significance. There have been substantial studies conducted on metal research. Accelerated experiments can shorten the test time, but there still differences real processes. Numerical simulation methods avoid radioactive experiments, it is difficult fully simulate a environment. The modeling...