A5069849760- Stroke Rehabilitation and Recovery
- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Neuroscience and Neuropharmacology Research
- Anesthesia and Neurotoxicity Research
- Cancer, Stress, Anesthesia, and Immune Response
- Neurogenesis and neuroplasticity mechanisms
- Venous Thromboembolism Diagnosis and Management
Heidelberg University
2017-2019
German Cancer Research Center
2019
University Hospital Heidelberg
2017-2019
National Center for Tumor Diseases
2019
Messer (Germany)
2018
Background and Purpose— We aimed to describe the safety efficacy of immediate mechanical thrombectomy (MT) in patients with large vessel occlusions low National Institutes Health Stroke Scale (NIHSS) versus best medical management. Methods— Patients from prospectively collected databases 6 international comprehensive stroke centers (distal intracranial internal carotid, middle cerebral artery-M1 M2 segments, or basilar artery without tandem occlusions) NIHSS 0 5 were identified divided into...
<h3>SUMMARY:</h3> While mechanical thrombectomy for large-vessel occlusions is now an evidence-based treatment, its efficacy and safety in minor stroke syndromes (NIHSS ≤ 5) not proved. We identified, our prospective data base, 378 patients with strokes the anterior circulation; 54 (14.2%) of these had proved occlusions. Eight (14.8%) were immediately treated thrombectomy, 6/54 (11.1%) after early neurologic deterioration, rest standard thrombolysis only. Rates successful recanalization...
Background: In patients with acute ischemic strokes (AIS) and milder symptoms (NIHSS</=5) harboring a large vessel occlusion (LVO) best clinical management is unclear. To describe the safety efficacy of immediate mechanical thrombectomy (MT) in LVO versus medical management, including rescue MT. Methods: Retrospective cohort study on consecutive for descriptive analysis regarding outcomes. From local prospectively run databases six international comprehensive stroke centers data was...
Abstract A network of communicating tumour cells established by microtubes (TMs) is supposed to mediate relevant aspects progression and resistance incurable gliomas. Moreover, neuronal activity has been shown foster malignant behavior glioma non-synaptic paracrine autocrine mechanisms. Here, we report an unexpected direct communication channel between neurons in multiple disease models as well astrocytomas glioblastomas (GBs) adult patients: functional bona fide chemical synapses formed...