A5079182166- Diverse Music Education Insights
- Taxation and Legal Issues
- bioluminescence and chemiluminescence research
- Neuroscience and Music Perception
- Neuroinflammation and Neurodegeneration Mechanisms
- Music Education and Analysis
- Musicians’ Health and Performance
- Circadian rhythm and melatonin
- Corporate Taxation and Avoidance
- Attention Deficit Hyperactivity Disorder
- Fiscal Policy and Economic Growth
- Taxation and Compliance Studies
- Nicotinic Acetylcholine Receptors Study
- Natural Compound Pharmacology Studies
- Neurogenesis and neuroplasticity mechanisms
- Legal and Policy Issues
- Legal and Constitutional Studies
- Diversity and Career in Medicine
- Nerve injury and regeneration
- Employment and Welfare Studies
- Business Law and Ethics
- Immune cells in cancer
- Legal and Regulatory Analysis
- Migration and Labor Dynamics
- Diaspora, migration, transnational identity
University of Kentucky
2023-2025
University of Maryland, College Park
2021-2023
University of North Carolina at Greensboro
2021
National Institute of Environmental Health Sciences
2004-2012
Research Triangle Park Foundation
2005-2012
National Institutes of Health
2006-2011
University College London
1996
Middlesex Hospital
1986
St Mary's Hospital
1986
Yavapai College
1980
Abstract Background: Apathy is a very common behavioural and psychological symptom across brain disorders. In the last decade, there have been considerable advances in research on apathy motivation. It thus important to revise diagnostic criteria published 2009. The main objectives were to: a) definition of apathy; b) update list dimensions; c) operationalise criteria; d) suggest appropriate assessment tools including new technologies. Methods: expert panel (N = 23) included researchers...
Apathy is common in neurocognitive disorders (NCD) but NCD-specific diagnostic criteria are needed.The International Society for CNS Clinical Trials Methodology Work Group convened an expert group and sought input from academia, health-care, industry, regulatory bodies. A modified Delphi methodology was followed, included extensive literature review, two surveys, meetings at international conferences, culminating a consensus meeting 2019.The final reached with more than 80% agreement on all...
Microglia-derived superoxide is critical for the inflammation-induced selective loss of dopaminergic (DA) neurons, but underlying mechanisms microglial activation remain poorly defined. Using neuron-glia and microglia-enriched cultures from mice deficient in MAC1 receptor (MAC1-/-), we demonstrate that lipopolysaccharide (LPS) treatment results lower TNFalpha response, attenuated DA absence extracellular production MAC1-/- cultures. Microglia accumulated fluorescently labeled LPS punctate...
β-Amyloid peptide (Aβ) is a major protein in the brain associated with Alzheimer's and Parkinson's diseases. The purpose of this study was to investigate role macrophage antigen-1 (MAC1) receptor, an integrin scavenger receptor microglia, subsequent signaling events mediating Aβ-induced neurotoxicity. We have previously reported that NADPH oxidase (PHOX) on microglia superoxide produced by PHOX are critical for loss dopaminergic neurons. However, upstream pathway production remains unclear....
Sexual harassment victims are taxable on their recoveries. Recoveries for personal injuries that not “physical” taxable, and the Internal Revenue Service most courts hold arising from physical. This is bad policy. Taxing a plaintiff’s recovery discourages lawsuits. And Congress, by requiring “physical injury” dismissing “emotional conditions” as physical, relied mistaken science. Courts have perpetuated this error even researchers now understand extreme stress releases hormones can...
The purpose of this study was to examine the demographic profile doctoral music recipients by discipline from 1984 2022. Using sociological institutionalist and feminist frameworks, I analyzed institution-level panel data Integrated Postsecondary Education Data System ( N = 3,461) characteristics in education, history/musicology, theory/composition, performance. number completers theory/composition remained relatively stable over 4 decades. performance increased nearly fourfold, 342 1,253...
The purpose of this study was to investigate issues equity in access, uptake, and outcomes high school music education the context an individual state, Maryland. I explored through four angles: (a) representation among students teachers, (b) factors associated with access courses, (c) student characteristics enrollment, (d) postsecondary enrollment who did not enroll music. Sample members included all enrolled a public Maryland belonging 2015 2016 ninth-grade cohort ( N = 55,500) teachers...
The purpose of this study was to investigate Maryland music teacher education program completers’ background and transition into the K–12 public school ( N = 700). Using data from Longitudinal Data System between 2008 2020, I examined characteristics associated with employment in schools, job responsibilities new teachers, schools which teachers were employed, how employed similar or dissimilar high they graduated. Overall, approximately 59% graduates subsequently taught schools. Most...
Over 30 states have experienced a shortage of music teachers in the past decade. The attrition early-career is one largest contributing factors to rising demand for nationally, but there lack rigorous empirical research examining characteristics associated with teachers. I leveraged data from Maryland Longitudinal Data System examine teachers' retention and patterns between 2013 2020 using descriptive statistics discrete-time survival analysis (N = 6430). On average, 74% retained their...
It has been reported that extracellular matrix (ECM) molecules regulate monocyte activation by binding with a 67 kDa nonintegrin laminin receptor (LR). As microgliosis is pivotal factor in propelling the progress of chronic neurodegeneration brain, we hypothesized LR may and subsequent neurotoxicity. Using 1-methyl-4-phenylpyridinium (MPP+) -treated C57 mice primary mesencephalic neuron-glia cultures as an vitro Parkinson's disease (PD) model, observed MPP+ treatment increased expression...
St. John's wort (SJW), an over-the-counter antidepressant, contains hypericin, which absorbs light in the UV and visible ranges. In vivo studies have determined that hypericin is phototoxic to skin our previous vitro with lens tissues it potentially human lens. To determine if might also be retina, we exposed retinal pigment epithelial (hRPE) cells 10−7 10−5 M hypericin. Fluorescence emission detected from (λex = 488 nm; λem 505 nm) confirmed uptake by RPE. Neither exposure alone nor reduced...
St. John's Wort (SJW), an over-the-counter antidepressant, contains hypericin, which absorbs light in the UV and visible ranges is phototoxic to skin. To determine if it also could be eye, we exposed human lens epithelial cells 0.1-10 microM hypericin irradiated them with 4 J/cm2 UV-A or 0.9 light. Neither exposure alone nor reduced cell viability. In contrast, combination underwent necrosis apoptosis. The ocular antioxidants lutein N-acetyl cysteine did not prevent damage. Thus, ingested...
The purpose of this study was to examine K–12 instrumental music education in North Carolina. Specifically, we investigated course offerings, teacher demographics, teaching responsibilities, and program funding. We administered a survey the members Carolina Music Educators Association listserv who indicated band or orchestra as their area. Participants identified themselves teachers ( n = 44), 173), hybrid both 17). Of schools that offered music, 95% 36% orchestra. More than 20% were “very...
The purpose of this study was to investigate the potential relationship between student enrollment trends in elective secondary music ensembles and ensemble teacher job turnover. Although is widely accepted as an important concern for educators a crude proxy measure quality, these normative beliefs have not been thoroughly examined empirically. This tested using data from State Longitudinal Data System link statewide high school workforce academic years 2012 2013 through 2019 2020. Two-way...
On September 17, 2015, the IRS and Treasury Department issued final, temporary, proposed regulations under section 871(m) of Internal Revenue Code that provide rules for withholding on “dividend equivalent payments” derivatives reference U.S. equity securities. In general, narrow class would have been subject to in 2013. For example, new regulations, a “simple contract” is not unless its delta 0.80 or more whereas, 2013 imposed if was at least 0.70. However, still require “price return only”...
The purpose of this study was to investigate the effect wearing earplugs on classical musicians’ pitch perception across three experimental conditions: no earplugs, foam and Etymotic earplugs. Participants were graduate undergraduate music majors attending a large school in southeastern United States ( N = 72). adjusted five complex stimulus tones (C#4, C#5, C#3, G#4, F#3) using continuous response digital interface until they believed interval tune with an oboe (C#4) reference tone. tended...
Abstract St. John's Wort (SJW), an over‐the‐counter antidepressant, contains hypericin, which absorbs light in the UV and visible ranges is phototoxic to skin. To determine if it also could be eye, we exposed human lens epithelial cells 0.1–10 μ M hypericin irradiated them with 4 J/cm 2 UV‐A or 0.9 light. Neither exposure alone nor reduced cell viability. In contrast, combination underwent necrosis apoptosis. The ocular antioxidants lutein N ‐acetyl cysteine did not prevent damage. Thus,...
This paper summarizes the second set of proposed "opportunity zone" regulations issued under section 1400Z-2 Internal Revenue Code, which were released on April 17, 2019.