A5033504713- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Intracranial Aneurysms: Treatment and Complications
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Cerebrovascular and Carotid Artery Diseases
- Hemodynamic Monitoring and Therapy
- Intensive Care Unit Cognitive Disorders
- Neurosurgical Procedures and Complications
- Meningioma and schwannoma management
- Respiratory Support and Mechanisms
- Trigeminal Neuralgia and Treatments
- Cardiac Ischemia and Reperfusion
- Sepsis Diagnosis and Treatment
- Optical Imaging and Spectroscopy Techniques
- Neonatal Respiratory Health Research
- Head and Neck Surgical Oncology
- S100 Proteins and Annexins
- Intraoperative Neuromonitoring and Anesthetic Effects
- Intraocular Surgery and Lenses
- Cardiac Arrest and Resuscitation
- Total Knee Arthroplasty Outcomes
- Spinal Fractures and Fixation Techniques
- Shoulder Injury and Treatment
- Spine and Intervertebral Disc Pathology
Stanford University
2021-2024
Stanford Medicine
2023
Hospital for Special Surgery
2011-2019
Washington University in St. Louis
2019
Hôpital Pasteur
2018
Cornell University
2013-2018
University of Florence
2011-2016
San Francisco VA Medical Center
2016
Azienda Ospedaliero-Universitaria Careggi
2012-2013
Introduction: Obesity has long been considered a risk factor for the development of various pathologies, yet evidence supporting increased perioperative mortality in obese individuals developing postoperative complications is limited. Therefore, we sought to characterize demographics and nonobese respiratory insufficiency (RI)/adult distress syndrome (ARDS) quantify impact obesity on in-hospital among this patient population utilizing data collected Nationwide Inpatient Sample (NIS)....
Total knee arthroplasty (TKA) can be associated with considerable postoperative pain. Ischemic preconditioning of tissue before inducing procedure-related underperfusion may reduce the inflammatory response, which further pain.In this prospective, randomized study, we aimed at evaluating impact ischemic on pain rest and during exercise; use medication; levels systemic prothrombotic local markers; length stay achievement physical therapy milestones.Sixty patients undergoing unilateral TKA...
BACKGROUND: Electroencephalographic (EEG) brain monitoring during general anesthesia provides information on hypnotic depth. We hypothesized that clinicians could be trained rapidly to recognize typical EEG waveforms occurring with volatile-based anesthesia. METHODS: This was a substudy of trial testing the hypothesis EEG-guided prevents postoperative delirium. The intervention 35-minute training session, summarizing changes Participants completed preeducational test, underwent training, and...
In Brief BACKGROUND: Hypotensive epidural anesthesia (HEA), as practiced at our institution, uses sympathetic blockade to achieve mean arterial blood pressure (MAP) of ≤50 mm Hg while administering epinephrine by infusion support the circulation. HEA has not been associated with gross adverse effects on neurologic outcome or cognitive function in postoperative period, suggesting adequate cerebral flow (CBF). However, use MAPs well below commonly accepted lower limit CBF autoregulation...
BACKGROUND: Unintended intraoperative awareness with recall (AWR) is a potential complication of general anesthesia. Patients typically report recollections (1) hearing sounds or conversations, (2) being unable to breathe move, (3), feeling pain, and/or (4) experiencing emotional distress. The purpose the current study was identify and further characterize AWR experiences identified through postoperative surveys large unselected adult surgical cohort. METHODS: This substudy prospective...
Background Delayed cerebral ischemia (DCI) following aneurysmal subarachnoid hemorrhage (aSAH) is associated with adverse neurological outcomes. Early and accurate diagnosis of DCI crucial to prevent infarction. This study aimed assess the diagnostic accuracy interrater agreement visual assessment neuroimaging perfusion maps detect in patients suspected vasospasm after aSAH. Methods In this case-control study, cases were adult aSAH who underwent magnetic resonance or computed tomography...
Prone positioning (PP) is necessary for surgical access during posterior spine procedure. However, physiological changes occur in the PP. Typical findings are a decrease arterial blood pressure and cardiac output that could potentially lead to an alteration cerebral perfusion. Therefore, we decided study flow velocity (CBFV) with transcranial Doppler ultrasonography evaluate effect of PP on hemodynamics.Twenty-two patients undergoing surgery were studied. General anesthesia was induced using...
Continuous popliteal nerve block is utilized for postoperative analgesia after foot and ankle surgery. Whether only the total dose of local anesthetic or combination concentration volume determine characteristics a continuous infusion remains currently unknown. We hypothesized reduction incidence insensate extremity in patients given ropivacaine 0.4% at 4 mL/h compared to 0.2% 8 mL/h.Sixty-four scheduled major surgery requiring catheter were studied. Thirty-three randomized receive with...
(Abstracted from Anesth Analg, 122:234–242, 2016) Sympathetic blockade has been used as a means to achieve mean arterial blood pressure (MAP) of less than 50 mm Hg while administering epinephrine by infusion support circulation. Adequate cerebral flow (CBF) appears have accomplished in such cases, leading researchers conclude that there is no association between hypotensive epidural anesthesia (HEA) administration and gross adverse effects on either neurological outcome or cognitive function.