A5074807366- Cardiac, Anesthesia and Surgical Outcomes
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Substance Abuse Treatment and Outcomes
- Hemodynamic Monitoring and Therapy
- Anesthesia and Neurotoxicity Research
- HIV, Drug Use, Sexual Risk
- Opioid Use Disorder Treatment
- Date Palm Research Studies
- Obstructive Sleep Apnea Research
- HIV/AIDS Research and Interventions
- Pain Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Cannabis and Cannabinoid Research
- Child and Adolescent Psychosocial and Emotional Development
- Adolescent Sexual and Reproductive Health
- Suicide and Self-Harm Studies
- Frailty in Older Adults
- Forensic Toxicology and Drug Analysis
- Sex work and related issues
- Patient Safety and Medication Errors
- Pediatric Pain Management Techniques
- Homelessness and Social Issues
- Child Abuse and Trauma
- Neuroscience of respiration and sleep
Washington University in St. Louis
2016-2025
University of Nebraska Medical Center
2023
Barro Colorado Island
2020
Quality Research
2018
Wright State University
2016
MSD K.K. (Japan)
2013
American Society of Anesthesiologists
2013
Barnes-Jewish Hospital
2013
Health Research and Educational Trust
2011
Food and Agriculture Organization of the United Nations
2010
<h3>Importance</h3> Intraoperative electroencephalogram (EEG) waveform suppression, often suggesting excessive general anesthesia, has been associated with postoperative delirium. <h3>Objective</h3> To assess whether EEG-guided anesthetic administration decreases the incidence of <h3>Design, Setting, and Participants</h3> Randomized clinical trial 1232 adults aged 60 years older undergoing major surgery receiving anesthesia at Barnes-Jewish Hospital in St Louis. Recruitment was from January...
In Brief BACKGROUND: Postoperative delirium is a common complication associated with increased morbidity and mortality, longer hospital stays, greater health care expenditures. Intraoperative electroencephalogram (EEG) slowing has been previously postoperative delirium, but the relationship between intraoperative EEG suppression not investigated. METHODS: this observational cohort study, 727 adult patients who received general anesthesia planned intensive unit admission were included....
With increased use of electronic medical records (EMRs), data mining on has great potential to improve the quality hospital treatment and increase survival rate patients. Early readmission prediction enables early intervention, which is essential preventing serious or life-threatening events, act as a substantial contributor reduce healthcare costs. Existing works predicting often focus certain vital signs diseases by extracting statistical features. They also fail consider skewness class...
Intraoperative electroencephalogram (EEG) waveform suppression, suggesting excessive general anesthesia, has been associated with postoperative delirium.
Background: Many orthopaedic surgical procedures can be performed with either regional or general anesthesia. We hypothesized that total hip arthroplasty anesthesia is associated less postoperative morbidity and mortality than Methods: This retrospective propensity-matched cohort study utilizing the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database included patients who had undergone from 2007 through 2011. After matching, logistic regression was...
Postoperative mortality occurs in 1-2% of patients undergoing major inpatient surgery. The currently available prediction tools using summaries intraoperative data are limited by their inability to reflect shifting risk associated with physiological perturbations. We sought compare similar benchmarks a deep-learning algorithm predicting postoperative 30-day mortality.We constructed multipath convolutional neural network model patient characteristics, co-morbid conditions, preoperative...
Persons in drug treatment with dependence were interviewed the NIMH Diagnostic Interview Schedule to ascertain DSM‐III‐R disorders. Lifetime prevalence rates 64% for alcohol dependence, 44% antisocial personality disorder (ASPD), 39% phobic disorders, 24% major depression, 12% dysthymia, 10% generalized anxiety disorder, 3% panic mania, obsessive compulsive 2% bulimia, 1% schizophrenia, and anorexia. When stratified by race age, significant main effects seen, but there no interactions except...
In Brief OBJECTIVE: To estimate the predictive ability of current obstructive sleep apnea (OSA) screening tools and individual questions in these at identifying pregnant women who have OSA. METHODS: A total 293 third-trimester patients were enrolled between 2010 2012, 248 had monitor results. Recruited participants completed a questionnaire consisting six OSA overnight portable monitoring. Predictive for compared with results diagnosis from monitoring was estimated using area under receiver...
The prevalence of substance abuse and other psychiatric disorders among physicians is not well-established. We determined differences in lifetime use, abuse/dependence as well disorders, comparing undergoing monitoring with a general population that had sought treatment for use.Participants were 99 referred to Physician's Health Program (PHP) because suspected impairment, who administered the Computerized Diagnostic Interview Schedule Version IV (CDIS-IV) assess presence disorders. Referred...
The relationship between substance use disorders and comorbid psychiatric conditions was investigated among 425 persons in drug treatment who met DSM‐III‐R criteria for dependence. Using the NIMH Diagnostic Interview Schedule to ascertain these dependent subjects, lifetime prevalence rates were 64% alcohol abuse/dependence, 44% antisocial personality disorder, 39% phobic disorders, 24% major depression, 12% dysthymia, 10% generalized anxiety disorder. We found that disorder phobias generally...
Ketamine is a general anaesthetic with anti-depressant effects at subanaesthetic doses. We hypothesised that intraoperative administration of ketamine would prevent or mitigate postoperative depressive symptoms in surgical patients.We conducted an international, randomised clinical trial testing the [0.5 mg kg-1 (Lo-K) 1.0 (Hi-K)] vs control [saline placebo (P)] patients ≥60 yr old undergoing major surgery anaesthesia. administered Patient Health Questionnaire-8 before operation, on day...
Abstract Background Postoperative delirium is a common complication that hinders recovery after surgery. Intraoperative electroencephalogram suppression has been linked to postoperative delirium, but it unknown if this relationship causal or merely marker of underlying cognitive abnormalities. The hypothesis study was intraoperative mediates nonzero portion the effect between preoperative abnormal cognition and delirium. Methods This prespecified secondary analysis Electroencephalography...
Abstract Objective Accurate estimations of surgical case durations can lead to the cost-effective utilization operating rooms. We developed a novel machine learning approach, using both structured and unstructured features as input, predict continuous probability distribution durations. Materials Methods The data set consisted 53 783 cases performed over 4 years at tertiary-care pediatric hospital. Features extracted included categorical (American Society Anesthesiologists [ASA] Physical...
Telemedicine may help improve care quality and patient outcomes. for intraoperative decision support has not been rigorously studied.
Background and objective While several experimental studies have demonstrated the neuroprotective role of volatile anesthetics after spinal cord injury (SCI), impact on improving neurologic outcomes in cord-injured patients is not known. Hence, this study aimed to examine functional chronic cervical SCI undergoing peripheral nerve transfer procedures. Methods We conducted a retrospective analysis involving adult with upper extremity paralysis procedures between September 1, 2015, January 31,...
EEG wicket rhythms are 6- to 11-Hz medium-to-high voltage bursts that sometimes misidentified as epileptogenic activity. The authors determined the clinical and features of patients with who had been incorrectly diagnosed epilepsy.Electroencephalographers at an epilepsy center re-read EEGs for referred management identified rhythms. On further evaluation, majority (54%; 25/46) these were found not have epilepsy. compared 25 wickets nonepileptic episodes those age- sex-matched partial-onset...
Several studies have attempted to understand the link among substance abuse, depression, and suicidal ideation (SI). Assessment of this is important develop specific interventions for persons in abuse treatment. This association was tested 990 drug users out treatment with significant criminal justice histories from two National Institute on Drug Abuse studies. The Diagnostic Interview Schedule Substance Module assessed DSM-III-R number depression criteria met, antisocial personality...
This study used latent class analysis to examine subpopulation membership based on self-reports of delinquent behaviors obtained from Australian youth. Three discrete identifiable classes were derived 51 indicators physical violence, property damage, minor infractions, drug use, and social delinquency. One youth engaged in primarily rule breaking norm violations including underage alcohol typical this age period. A second was more actively emphasizing trespassing, various forms disobedience....
The date palm (Phoenix dactylifera L) is the most important crop of Gulf region in Middle-East. Kingdom Saudi Arabia with an estimated 25 million palms produces nearly a tones dates annually good potential for exporting surplus produce. In order to standardize quality norms major cultivars Kingdom, studies were taken up at National Date Palm Research Centre, Al Hassa, ascertain fruit characteristics (Tamar stage) Khalas, Sheshi and Reziz respect weight (g) , size (length breath), number...