A5028090559- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Neurotoxicity Research
- Intensive Care Unit Cognitive Disorders
- Airway Management and Intubation Techniques
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- EEG and Brain-Computer Interfaces
- Tracheal and airway disorders
- Restless Legs Syndrome Research
- Anesthesia and Pain Management
- Sleep and Wakefulness Research
- Mechanical Circulatory Support Devices
- Thermal Regulation in Medicine
- Ultrasound in Clinical Applications
- Neonatal Respiratory Health Research
- Pancreatitis Pathology and Treatment
- Congenital Heart Disease Studies
- Restraint-Related Deaths
- Optical Imaging and Spectroscopy Techniques
- Hemostasis and retained surgical items
- Healthcare Technology and Patient Monitoring
- Cystic Fibrosis Research Advances
- Dental Anxiety and Anesthesia Techniques
- Organ Transplantation Techniques and Outcomes
University of Bern
2014-2024
University Hospital of Bern
2007-2024
Hirslanden Klinik Aarau
2021-2023
GGD Amsterdam
2021
Novem (Netherlands)
2021
Medical University of Vienna
2021
Washington University in St. Louis
2011-2020
Swiss Continence Foundation
2018
HeidelbergCement (Germany)
2012
Siena Biotech (Italy)
2012
Background: Many orthopaedic surgical procedures can be performed with either regional or general anesthesia. We hypothesized that total hip arthroplasty anesthesia is associated less postoperative morbidity and mortality than Methods: This retrospective propensity-matched cohort study utilizing the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database included patients who had undergone from 2007 through 2011. After matching, logistic regression was...
Hypnotic depth during anesthesia affects electroencephalography waveforms and electroencephalogram-derived indices, such as the bispectral index (BIS). Titrating anesthetic administration against BIS assumes reliable relationships between values, electroencephalogram waveforms, effect site concentration, beyond loss of responsiveness. Associations among BIS, end-tidal concentrations (ETAC), patient characteristics were examined maintenance, using B-Unaware trial data.Pharmacokinetically...
We observed a remarkable increase in the number of young patients who presented with lung emphysema and secondary spontaneous pneumothorax (SSP) at our institution for over period 30 months; most them have common history marijuana abuse.Retrospective case series.Seventeen bullous were systematically evaluated months. All regular smokers. Clinical history, chest X-ray, CT-scan, function test, laboratory histological examinations assessed. compared findings this group (group I) non-marijuana...
The incidence, prediction and mortality outcomes of intraoperative postoperative cardiac arrest requiring cardiopulmonary resuscitation (CPR) in surgical patients are under investigated have not been studied concurrently a single study.A retrospective cohort study was conducted using the American College Surgeons National Surgical Quality Improvement Program data between 2008 2012. Firth's penalized logistic regression used to incidence identify risk factors for intra- CPR 30-day mortality....
The Bispectral Index (BIS) reportedly reflects anesthetic depth. It is recommended that agents should be titrated to maintain the BIS between 40 and 60 arbitrary units during anesthesia. For anesthesia providers follow this recommendation, monitor predictably affected by different have good interpatient intrapatient reproducibility. authors hypothesized when two BISxp devices (Aspect Medical Systems, Newton, MA) are placed concurrently on same patient, their readings concordant throughout...
Background Anesthesia studies using high-flow, humidified, heated oxygen delivered via nasal cannulas at flow rates of more than 50 l · min–1 postulated a ventilatory effect because carbon dioxide increased lower levels as reported earlier. This study investigated the increase arterial partial pressure between different 100% in elective anesthetized and paralyzed surgical adults before intubation. Methods After preoxygenation standardized anesthesia induction with nondepolarizing...
<h3>Introduction</h3> Postoperative delirium is one of the most common complications major surgery, affecting 10–70% surgical patients 60 years and older. Delirium an acute change in cognition that manifests as poor attention illogical thinking associated with longer intensive care unit (ICU) hospital stay, long-lasting cognitive deterioration increased mortality. Ketamine has been used anaesthetic drug for over 50 established safety record. Recent research suggests that, addition to...
Background After cardiac surgery with cardiopulmonary bypass (CPB), acquired coagulopathy often leads to post-CPB bleeding. Though multifactorial in origin, this is aggravated by deficient fibrinogen levels. Objective To assess whether laboratory and thrombelastometric testing on CPB can predict plasma immediately after weaning. Patients / Methods This prospective study 110 patients undergoing major cardiovascular at risk of bleeding compares level (Clauss method) function (fibrin-specific...
The aim of the study was to determine if training in transesophageal echocardiography (TEE) using a TEE simulator improves ability novice operators perform and interpret focused critical care TEE.In this prospective, randomized, controlled with blinded outcome assessment, 44 intensive unit trainees were randomly assigned control group receiving 4 hours lecture-based only, or an intervention which additionally trained for simulator. After intervention, each participant performed 2 TEEs...
Other than clinical observation of a patient's vegetative response to nociception, monitoring the hypnotic component general anesthesia (GA) and unconsciousness relies on electroencephalography (EEG)-based indices. These indices exclusively based frontal EEG activity neglect an important observation. One main hallmarks transitions from wakefulness GA is shift in alpha oscillations (7.5-12.5 Hz activity) occipital brain regions toward anterior ("alpha anteriorization"). Monitoring degree this...
It is well-known that additive noise affects the stability of nonlinear systems. Using a network composed two interacting populations, detailed stochastic and non-linear analysis demonstrates increasing intensity iid induces phase transition from spectrally broad-band state to phase-coherent oscillatory state. Corresponding coherence resonance-like system behaviour described analytically for as well. Stochastic transitions were also found occur non-iid induced by increased heterogeneity,...
Background High-flow nasal oxygenation is increasingly used during sedation procedures and general anesthesia in apneic patients. Transcutaneous CO 2 (p tc )-monitoring to monitor hypercapnia. This study investigated p -monitoring oxygenation. Methods We included 100 patients scheduled for elective surgery under this secondary analysis of a randomized controlled trial. Before surgery, we collected measured by TCM4 TCM5 monitors arterial blood gas (ABG) measurements every two minutes 15...
Abstract Apnoeic oxygenation has experienced a resurgence in interest critical care and perioperative medicine. However, its effect on cerebral factors influencing it, have not yet been investigated detail. By using near-infrared spectroscopy, we intended to provide further evidence for the safety of apnoeic increase our understanding association between perfusion, haemodynamic, respiratory demographic factors. In this secondary analysis prospective randomized controlled noninferiority...
BACKGROUND With an ageing global population, it is important to individualise titration of anaesthetics according age and by measuring their effect on the brain. A recent study reported that during general surgery, given concentration volatile anaesthetics, expressed as a fraction minimum alveolar (MAC fraction), decreases around only 3% per age-decade, which less than 6% expected from age-adjusted MAC. Paradoxically, despite excessive dosing, Bispectral index (BIS) values also increased....