A5101959111- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Congenital Heart Disease Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Gallbladder and Bile Duct Disorders
- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Pain Management and Opioid Use
- Intensive Care Unit Cognitive Disorders
- Hip and Femur Fractures
- Gastrointestinal disorders and treatments
- Opioid Use Disorder Treatment
- Metabolism and Genetic Disorders
- Delphi Technique in Research
- Healthcare Operations and Scheduling Optimization
- Cardiac Arrest and Resuscitation
- Congenital Diaphragmatic Hernia Studies
- Rabies epidemiology and control
- Health Systems, Economic Evaluations, Quality of Life
- Congenital Anomalies and Fetal Surgery
- Frailty in Older Adults
- Congenital heart defects research
- Nausea and vomiting management
- Anesthesia and Neurotoxicity Research
- Pulmonary Hypertension Research and Treatments
Shyam Shah Medical College
2020-2024
University of California, San Francisco
2021-2024
UCSF Benioff Children's Hospital
2022
Washington University in St. Louis
2011-2021
Duke University
2019
Quality Research
2018
Wright State University
2016
St. Louis Children's Hospital
2015
King George's Medical University
2010-2013
Indian Space Research Organisation
2013
Abstract Objective Accurate estimations of surgical case durations can lead to the cost-effective utilization operating rooms. We developed a novel machine learning approach, using both structured and unstructured features as input, predict continuous probability distribution durations. Materials Methods The data set consisted 53 783 cases performed over 4 years at tertiary-care pediatric hospital. Features extracted included categorical (American Society Anesthesiologists [ASA] Physical...
Methadone is frequently administered to adults experiencing anesthesia and receiving pain treatment. pharmacokinetics in are well characterized, including the perioperative period. also used children. There is, however, no information on methadone children of any age. The purpose this investigation was determine intravenous undergoing surgery. Perioperative opioid-sparing effects were assessed.Eligible subjects 5-18 yr general surgery, with an anticipated postoperative inpatient stay...
<h3>Introduction</h3> Mortality and morbidity following surgery are pressing public health concerns in the USA. Traditional prediction models for postoperative adverse outcomes demonstrate good discrimination at population level, but ability to forecast an individual patient’s trajectory real time remains poor. We propose apply machine learning techniques perioperative time-series data develop algorithms predicting outcomes. <h3>Methods analysis</h3> This study will include all adult...
In Brief BACKGROUND: Nitrous oxide inactivates vitamin B12, inhibits methionine synthase, and consequently increases plasma total homocysteine (tHcy). Prolonged exposure to nitrous can lead neuropathy, spinal cord degeneration, even death in children. We tested the hypothesis that anesthesia causes a significant increase tHcy METHODS: Twenty-seven children (aged 10–18 years) undergoing elective major spine surgery were enrolled, serial samples from 0 96 hours after induction obtained. The...
Abstract Background The impact of surgery on health is only appreciated long after hospital discharge. Furthermore, patients’ perceptions postoperative are not routinely ascertained. authors instituted the Systematic Assessment and Targeted Improvement Services Following Yearlong Surgical Outcomes Surveys (SATISFY-SOS) registry to evaluate based patient-reported outcomes (PROs). Methods This article describes methods establishing SATISFY-SOS from an unselected surgical population, combining...
Congenital lumbar hernia is an uncommon anomaly with only few cases reported in the English literature. This study was done to incidence, associated conditions, management and complications of congenital repair paediatric patients.Retrospective all patients over a period 20 years (January 1990 January 2010) analysed.A total 18 (two bilateral hernias) were encountered this series. All age group 1 day 6 years. operated by open technique. Primary 14 prosthetic meshplasty two. Two could not be...
Falls are common and linked to morbidity. Our objectives were characterize postoperative falls, determine whether preoperative falls independently predicted (primary outcome), functional dependence, quality of life, complications, readmission.This prospective cohort study included 7982 unselected patients undergoing elective surgery. Data collected from the medical record, a baseline survey, follow-up surveys approximately 30days one year after surgery.Fall rates (per 100 person-years)...
Abstract Cardiac catheterization remains the gold standard for diagnosis and management of pediatric pulmonary hypertension (PH). There is lack consensus regarding optimal anesthetic airway regimen. This retrospective study describes anesthetic/airway experience our single center cohort PH patients undergoing catheterization, in which obtaining hemodynamic data during spontaneous breathing preferential. A total 448 catheterizations were performed 232 patients. Of 379 cases that began with a...
Frailty is an important concept in the care of older adults although controversy remains regarding its defining features and clinical utility. Both Fried phenotype Rockwood deficit accumulation approaches cast frailty as a "burden" without exploring relative salience cardinal markers their relevance to patient. New multifactorial perspectives require reliable assessment that can validly predict postoperative health outcomes.In retrospective study 2828 unselected surgical patients, we used...
Abstract Editor’s Perspective What We Already Know about This Topic Article Tells Us That Is New Background Opioids are a mainstay of perioperative analgesia. Opioid use in children with obstructive sleep apnea is challenging because assumptions for increased opioid sensitivity and assumed risk opioid-induced respiratory depression compared to without apnea. These have not been rigorously tested. investigation tested the hypothesis that an pharmacodynamic miotic depressant effects prototypic...
Abstract Background Anesthesiologists need tools to accurately track postoperative outcomes. The accuracy of patient report in identifying a wide variety complications after diverse surgical procedures has not previously been investigated. Methods In this cohort study, 1,578 adult patients completed survey at least 30 days their procedure asking if they had experienced any 18 while the hospital surgery. Patient responses were compared results an automated electronic chart review and (for...
BACKGROUND: Unintended intraoperative awareness with recall (AWR) is a potential complication of general anesthesia. Patients typically report recollections (1) hearing sounds or conversations, (2) being unable to breathe move, (3), feeling pain, and/or (4) experiencing emotional distress. The purpose the current study was identify and further characterize AWR experiences identified through postoperative surveys large unselected adult surgical cohort. METHODS: This substudy prospective...
Introduction: Rabies is a zoonotic disease that can be fatal and continues to impose significant financial burden on developing countries. Recently, there have been advancements in the introduction of cell culture vaccines immunoglobulin, as well approval Intradermal (ID) schedules for vaccine administration. Aim: To assess knowledge doctors Rewa District regarding National Guidelines Prophylaxis 2019. Materials Methods: A cross-sectional study was conducted, involving from tertiary...
Background: Each year, over 300 million people undergo surgical procedures worldwide. Despite efforts to improve outcomes, postoperative morbidity and mortality are common. Many patients experience complications as a result of either medical error or failure adhere established clinical practice guidelines. This protocol describes trial comparing telemedicine-based decision support system, the Anesthesiology Control Tower (ACT), with enhanced standard intraoperative care. Methods: study is...
In Brief BACKGROUND: Prolonged administration of nitrous oxide causes an increase in plasma homocysteine children via vitamin B12 inactivation. However, it is unclear whether doses used clinical practice cause adverse hematological effects pediatric patients. METHODS: This retrospective study included 54 patients undergoing elective spinal surgery: 41 received throughout anesthesia (maintenance group), 9 for induction and/or emergence (induction/emergence and 4 did not receive (nitrous...
INFANTS with hypotonia of unknown etiology pose a unique challenge as many the potential diagnoses have major, often conflicting, anesthetic management implications. The differential diagnosis is long and includes possibilities such Duchenne muscular dystrophy, central core disease, multiminicore disease. Intravenous techniques are recommended because hyperkalemia or malignant hyperthermia associated use volatile anesthetics. However, infants also mitochondrial disorders. In children...
No study has rigorously explored the characteristics of surgical patients with recent preoperative falls. Our objective was to describe essential features falls and determine whether they are associated functional dependence poor quality life.