A5100605902- Tactile and Sensory Interactions
- Interactive and Immersive Displays
- Gaze Tracking and Assistive Technology
- Context-Aware Activity Recognition Systems
- Speech and Audio Processing
- Hand Gesture Recognition Systems
- Human Pose and Action Recognition
- Music and Audio Processing
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Speech and dialogue systems
- Spine and Intervertebral Disc Pathology
- Coronary Interventions and Diagnostics
- Cancer Immunotherapy and Biomarkers
- Innovative Human-Technology Interaction
- Virtual Reality Applications and Impacts
- Advanced Image Processing Techniques
- Hearing Loss and Rehabilitation
- Vascular Procedures and Complications
- Indoor and Outdoor Localization Technologies
- Catalytic C–H Functionalization Methods
- Advanced Steganography and Watermarking Techniques
- AI in Service Interactions
- Heart Rate Variability and Autonomic Control
- Mobile Crowdsensing and Crowdsourcing
Tsinghua University
2016-2025
Fujian Provincial Cancer Hospital
2024-2025
Beijing Luhe Hospital Affiliated to Capital Medical University
2022-2024
NARI Group (China)
2024
Human Factors (Norway)
2024
Shenyang Pharmaceutical University
2024
University of Washington
2021-2023
Chengdu University of Traditional Chinese Medicine
2020-2023
Jinshan Hospital of Fudan University
2023
Qinghai University
2023
Mucopolysaccharidosis Type I, Hurler's Syndrome, is a lysosomal storage disorder that affects the brain. The missing enzyme, alpha-L-iduronidase (IDUA), does not cross blood-brain barrier (BBB). To enable BBB transport of human IDUA was fused to carboxyl terminus heavy chain chimeric monoclonal antibody (MAb) insulin receptor (HIR). HIRMAb crosses on endogenous receptor, and acts as molecular Trojan horse ferry into brain IDUA. Transfection COS cells resulted in high levels enzyme activity...
Most current audio steganographic methods are content non-adaptive which have poor security and low embedding capacity. This paper proposes a generalized adaptive Huffman code mapping (AHCM) framework for obtaining higher secure payload. To avoid the frame-offset effect of codec, we first establish distortion-limited suppressible space, realizes data by using equal-length entropy codes. Furthermore, stego key is used to dynamically build each frame improving acoustic imperceptibility...
Remote photoplethysmography (rPPG) is an attractive method for noninvasive, convenient and concomitant measurement of physiological vital signals. Public benchmark datasets have served a valuable role in the development this technology improvements accuracy over recent years. However, there remain gaps public datasets. First, despite ubiquity cameras on mobile devices, are few recorded specifically with phone cameras. Second, most relatively small therefore limited diversity, both appearance...
Abstract Glial‐derived neurotrophic factor (GDNF) is a neurotrophin that could be developed as neurotherapeutic for Parkinson's disease, stroke, and motor neuron disease. However, GDNF does not cross the blood–brain barrier (BBB). Human was re‐engineered by fusion of mature protein to carboxyl terminus chimeric monoclonal antibody (MAb) human insulin receptor (HIR). The HIRMAb‐GDNF bi‐functional, both binds HIR, trigger receptor‐mediated transport across BBB, (GFR)‐α1, activate...
Reading is an important aspect of a child's development. outcome heavily dependent on the level engagement while reading. In this paper, we present FOCUS, EEG-augmented reading system which monitors in real time, and provides contextual BCI training sessions to improve engagement. A laboratory experiment was conducted assess validity system. Results showed that FOCUS could significantly terms both EEG-based measurement teachers' subjective measure outcome.
Ad-hoc wireless device pairing enables impromptu interactions in smart spaces, such as resource sharing and remote control. The experience is mainly determined by the association process, during which users express their intentions between advertising scanning device. Currently, most devices are associated selecting advertiser's name from a list displayed on scanner's screen, becomes less efficient often misplaced number of increases. In this paper, we propose Tap-to-Pair, spontaneous...
The treatment of non-small cell lung cancer (NSCLC) with immune checkpoint inhibitors (ICIs) has been proven to induce lasting tumor remission. Screening suitable populations for immunotherapy through predictive markers is an important approach improving the clinical benefits patients. Evidence shown that there may be a close connection between NOTCH signaling and microenvironment (TME). Hence, we explored impact mutation status on prognosis NSCLC patients treated aim apply greatest extent...
Despite a rich history of investigating smartphone overuse intervention techniques, AI-based just-in-time adaptive (JITAI) methods for reduction are lacking. We develop Time2Stop, an intelligent, adaptive, and explainable JITAI system that leverages machine learning to identify optimal timings, introduces interventions with transparent AI explanations, collects user feedback establish human-AI loop adapt the model over time. conducted 8-week field experiment (N=71) evaluate effectiveness...
Artificial neural networks (ANNs) can help camera-Based Remote Photoplethysmography (rPPG) in measuring cardiac activity and physiological signals from facial videos, such as pulse wave, heart rate respiration with better accuracy. However, most existing ANN-based methods require substantial computing resources, which poses challenges for effective deployment on mobile devices. Spiking (SNNs), the other hand, hold immense potential energy-efficient deep learning owing to their binary...
While just-in-time interventions (JITIs) have effectively targeted common health behaviors, individuals often unique needs to intervene in personal undesirable actions that can negatively affect physical, mental, and social well-being. We present WatchGuardian, a smartwatch-based JITI system empowers users define custom for these with small number of samples. For the model detect new based on limited data samples, we developed few-shot learning pipeline finetuned pre-trained inertial...
Driver decision quality in take-overs is critical for effective human-Autonomous Driving System (ADS) collaboration. However, current research lacks detailed analysis of its variations. This paper introduces two metrics--Actual Achieved Gain (AAG) and Optimal Perceived (OPG)--to assess quality, with OPG representing optimal decisions AAG reflecting actual outcomes. Both are calculated as weighted averages perceived gains losses, influenced by ADS accuracy. Study 1 (N=315) used a 21-point...
Abstract Background Radial artery plaque (RAP) can influence the function of arterial conduits after revascularization and hinder maturation arteriovenous fistulas in patients undergoing hemodialysis patients. However, preferred vivo sites for RAP development have not been systematically investigated. This study measured evaluated to map distribution radial (RA) using optical coherence tomography (OCT). Methods OCT images entire RA 300 at 1 mm intervals were analyzed assess phenotypes...
Compared with conventional transradial access (TRA), distal radial (DRA) is rarely used for percutaneous coronary intervention (PCI) in patients ST-elevation myocardial infarction (STEMI) and may be beneficial to prevent artery occlusion (RAO). We aimed evaluate the incidence of RAO between DRA TRA 24 h after primary PCI STEMI. This a single-center, open-label, prospective, randomized controlled trial conducted at Beijing Luhe Hospital, China, January 2022 July 2023. Five hundred twenty...
Touch interaction on smartwatches suffers from the awkwardness of having to use two hands and "fat finger" problem. We present Float, a wrist-to-finger input approach that enables one-handed touch-free target selection with high efficiency precision using only commercially-available built-in sensors. With user tilts wrist point performs an in-air finger tap click. To realize we first explore appropriate motion space for tilt determine clicking action (finger tap) through user-elicitation...
This paper presents an effective steganalytic scheme based on CNN for detecting MP3 steganography in the entropy code domain. These steganographic methods hide secret messages into compressed audio stream through Huffman substitution, which usually achieve high capacity, good security and low computational complexity. First, unlike most previous methods, quantified modified DCT (QMDCT) coefficients matrix is selected as input data of proposed network. Second, a pass filter used to extract...
Temporal synchronous target selection is an association-free technique: users select a by generating signals (e.g., finger taps and hand claps) in sync with its unique temporal pattern. However, classical pattern set design input recognition algorithm of such techniques did not leverage users' behavioral information, which limits their robustness to imprecise inputs. In this paper, we improve these two key components modeling interaction behavior. the first user study, asked tap blinking...
We present DualRing, a novel ring-form input device that can capture the state and movement of user's hand fingers. With two IMU rings attached to thumb index finger, DualRing sense not only absolute gesture relative ground but also pose among segments. To enable natural thumb-to-finger interaction, we develop high-frequency AC circuit for on-body contact detection. Based on sensing information outline interaction space divide it into three sub-spaces: within-hand hand-to-surface...
Face orientation can often indicate users' intended interaction target. In this paper, we propose FaceOri, a novel face tracking technique based on acoustic ranging using earphones. FaceOri leverage the speaker commodity device to emit an ultrasonic chirp, which is picked up by set of microphones user's earphone, and then processed calculate distance from each microphone device. These measurements are used derive with respect We conduct ground truth comparison user study evaluate FaceOri's...
Smartphone overuse is related to a variety of issues such as lack sleep and anxiety. We explore the application Self-Affirmation Theory on smartphone intervention in just-in-time manner. present TypeOut, technique that integrates two components: an in-situ typing-based unlock process improve user engagement, self-affirmation-based typing content enhance effectiveness. hypothesize integration self-affirmation can better reduce overuse. conducted 10-week within-subject field experiment (N=54)...
Conventional transradial access (TRA) has been the preferred for coronary intervention. Recently, distal radial (DRA) is introduced as an alternative choice to reduce artery occlusion (RAO) risk. The study sought assess impact of DRA on early RAO using Doppler ultrasound in patients with ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous intervention (PCI).This a prospective, single-center, open-label randomized clinical trial which indications PCI from...