- Synthesis and biological activity
- Sulfur-Based Synthesis Techniques
- Organophosphorus compounds synthesis
- Synthesis and Catalytic Reactions
- Crystallization and Solubility Studies
- Chemical Synthesis and Reactions
- X-ray Diffraction in Crystallography
- Phenothiazines and Benzothiazines Synthesis and Activities
- Enzyme function and inhibition
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Metal complexes synthesis and properties
- Computational Drug Discovery Methods
- Corrosion Behavior and Inhibition
- Phosphorus compounds and reactions
- Multicomponent Synthesis of Heterocycles
- Organic and Inorganic Chemical Reactions
- Chemical Synthesis and Analysis
- Concrete Corrosion and Durability
- Asymmetric Hydrogenation and Catalysis
- Inorganic and Organometallic Chemistry
- Synthesis and Biological Evaluation
- Microwave-Assisted Synthesis and Applications
- Electrochemical Analysis and Applications
- Hydrogen embrittlement and corrosion behaviors in metals
Badji Moktar-Annaba University
2015-2024
École Normale Supérieure de Constantine
2024
Laboratoire de Chimie Organique
2006-2022
Laboratoire des Biomolécules
2015-2017
Faculty (United Kingdom)
2014-2017
State Key Laboratory of Applied Organic Chemistry
2015-2017
Division of Chemistry
2014-2017
Laboratoire de Chimie
2004-2015
Institute of Bioorganic Chemistry
2014
Bakhtar University
2012
The effects of cysteine (Cys) and l-methionine (l-Met) on copper corrosion inhibition were examined in 1 M HNO3 solution for short long exposure times. Potentiodynamic polarization (PDP) electrochemical impedance spectroscopy (EIS) used. EIS determined the potential zero charges (PZC) inhibitor solution. SEM AFM have been used to study material surfaces. Energy-dispersive X-ray (EDS) was identify surface elemental composition. DFT molecular dynamics simulations explored interaction between...
In this work, Schiff bases and Thiazolidin-4-ones, were synthesized using Sonication Microwave techniques, respectively. The base derivatives (3a–b) via the reaction of Sulfathiazole (1) with benzaldehyde (2a–b), followed by synthesis 4-thiazoledinone (4a–b) cyclizing through thioglycholic acid. All compounds characterized spectroscopic techniques such as FT IR, NMR HRMS. tested for their in vitro antimicrobial antioxidant vivo cytotoxicity hemolysis ability. displayed better activity low...
In this study, a series of thiazolidine-2,4-dione derivatives
This study investigates the inhibitory effects of 2-(2,4,5-trimethoxy benzylidene) hydrazine carbothioamide (TMBHCA) on corrosion carbon steel in a 1 M HCl solution across various concentrations. The assessment employs comprehensive approach, combining gravimetric analysis, potentiodynamic polarization tests, and electrochemical impedance spectroscopy (EIS). Additionally, scanning electron microscopy (SEM) quantum chemical calculations are employed to provide thorough understanding...
In the present work, a series of novel pyridine carboxamides 3(a-h) were synthesized and screened with antibacterial activity. This research explores application Density Functional Theory (DFT) in studying biological systems at quantum mechanical level, particularly context drug design. DFT offers streamlined approach to calculations, making it indispensable various scientific fields, for its exceptional accuracy, reduced computational time, cost-effectiveness has become pivotal tool...
Natural and fragrant compounds, essential oils (EOs) extracted from plants through hydrodistillation, are gaining popularity as eco-friendly sustainable agents to protect metals alloys corrosion in acidic environments. This research focused on extracting characterizing an EO obtained the Cuminum cyminum (CC) plant native India. The study aimed evaluate inhibitory properties of this mild steel a 0.5 M HCl solution at different concentrations. Various analytical techniques, including...
Dehydroacetic acid thiosemicarbazone (DHATSC) was tested for its ability to suppress corrosion on mild steel XC38 (MS XC38) by measuring effects electrochemical impedance spectroscopy (EIS), weight loss (WL), and potentiodynamic polarization (PDP). Using tests polarization, the inhibiting efficiency (IE) of DHATSC MS in 1.0 M HCl solution calculated. The data showed that highly inhibitory, with increasing effectiveness as inhibitor concentration increased. In 1 HCl, PDP curves a mixed-type...
Remdesivir and hydroxychloroquine derivatives form two important classes of heterocyclic compounds. They are known for their anti-malarial biological activity. This research aims to analyze the physicochemical properties remdesivir compounds by computational approach. DFT, docking, POM analyses also identify antiviral pharmacophore sites both The activity compound's in presence zinc sulfate azithromycin is evaluated through its capacity coordinate transition metals (M = Cu, Ni, Zn, Co, Ru,...
Colorectal cancer oncogenesis is linked to dysbiosis, oxidative stress and overexpression of CDK2. The 4H-pyran scaffold considered an antitumoral, antibacterial antioxidant lead as well a CDK2 inhibitor. Herein, certain derivatives were evaluated antibacterial, cytotoxic agents against HCT-116 cells. Derivatives 4g 4j inhibited all the tested Gram-positive isolates, except for B. cereus (ATCC 14579), with lower IC50 values (µM) than ampicillin. In addition, demonstrated strongest DPPH...