A5101429158- Reconstructive Surgery and Microvascular Techniques
- Orthopedic Surgery and Rehabilitation
- Bone fractures and treatments
- Elbow and Forearm Trauma Treatment
- Shoulder Injury and Treatment
- Osteoarthritis Treatment and Mechanisms
- Heterotopic Ossification and Related Conditions
- Inflammatory mediators and NSAID effects
- Tendon Structure and Treatment
- Cervical and Thoracic Myelopathy
- Organ and Tissue Transplantation Research
- Metabolomics and Mass Spectrometry Studies
- Bone Metabolism and Diseases
- Interactive and Immersive Displays
- Orthopaedic implants and arthroplasty
- Spine and Intervertebral Disc Pathology
- Radiomics and Machine Learning in Medical Imaging
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Knee injuries and reconstruction techniques
- Cerebrovascular and genetic disorders
- Reconstructive Facial Surgery Techniques
- Vitamin C and Antioxidants Research
- Surgical Sutures and Adhesives
- Gaze Tracking and Assistive Technology
Tengzhou Central People's Hospital
2023-2025
Jining Medical University
2023-2024
Xuzhou Medical College
2023
Nanjing Drum Tower Hospital
2023
Second Affiliated Hospital of Guangzhou Medical University
2022
Guangzhou Medical University
2022
Harbin University of Science and Technology
2020
Soochow University
2017-2019
Shanghai Sixth People's Hospital
2009-2018
Wuxi Ninth People's Hospital
2017-2018
Abstract Acquired heterotopic ossification (HO) is a painful and debilitating disease characterized by extraskeletal bone formation after injury. The exact pathogenesis of HO remains unknown. Here we show that TGF-β initiates promotes in mice. We find calcified cartilage newly formed resorb osteoclasts onset HO, which leads to high levels active recruit mesenchymal stromal/progenitor cells (MSPCs) the microenvironment. Transgenic expression tendon induces spontaneous whereas systemic...
Abstract Osteochondral defects affect both the articular cartilage and underlying subchondral bone, but poor osteochondral regeneration is still a daunting challenge. Although tissue engineering technology provides promising approach for repair, an ideal biphasic scaffold in high demand with regards to proper biomechanical strength. In this study, oriented poly( l ‐lacticacid)‐ co ‐poly( ε ‐caprolactone) P(LLA‐CL)/collagen type I(Col‐I) nanofiber yarn mesh, fabricated by dynamic liquid...
Oxidative stress and neuronal dysfunction caused by intracerebral haemorrhage (ICH) can lead to secondary injury. The m6A modification has been implicated in the progression of ICH. This study aimed investigate role reader YTHDC2 ICH-induced ICH models were established rats using autologous blood injection, cell induced with Hemin. Experiments conducted overexpress YTH domain containing 2 (YTHDC2) examine its effects on dysfunction, brain injury, ferritinophagy. RIP-qPCR METTL3 silencing...
Abstract The skeletal system is crucial for supporting bodily functions, protecting vital organs, facilitating hematopoiesis, and storing essential minerals. Skeletal homeostasis, which includes aspects such as bone density, structural integrity, regenerative processes, normal function. Autophagy, an intricate intracellular mechanism degrading recycling cellular components, plays a multifaceted role in metabolism. It involves sequestering waste, damaged proteins, organelles within...
Background: Various methods are available to treat the stiff elbow. However, there is no consensus on which one most useful. This study involves effects of combination arthrolysis by lateral and medial approaches hinged external fixation in treatment Patients: We treated 12 patients with elbows using a fixation. The was applied elbow for complete soft-tissue release, mainly rehabilitation stability after arthrolysis. With help fixation, nonsurgical including exercises effectively performed...
The present study investigated the effectiveness of celecoxib in preventing formation joint adhesions. Rabbit models adhesion were created and rabbits two treatment groups orally administered or ibuprofen (as a positive control) for 30 days. Rabbits control group did not receive any treatment. Following 30‑day experimental period, inhibitory effects on assessed using number methods, including macroscopic appearance, histology contracture angle. Thick fibrous adhesions developed knees group....
Elbow stiffness is a well-recognized complication following elbow trauma, but little information available regarding the surgical treatment of in children and adolescents. This article presents results open arthrolysis with twin incisions hinged external fixator to treat severe contracture Twenty-one patients (mean age, 14.9 years; range, 7–19 years) were evaluated. All underwent surgery using combined mediolateral approach address contracture. Mayo score range motion (ROM) measured...
Background: Cold exposure (CE) can effectively modulate adipose tissue metabolism and improve metabolic health. Although previous metabolomics studies have primarily focused on analyzing one or two samples from serum, brown (BAT), white (WAT), liver samples, there is a significant lack of simultaneous analysis multiple tissues regarding the changes induced by CE in mice. Therefore, our study aims to investigate profiles major involved. Methods: A total 14 male C57BL/6J mice were randomly...
Abstract Moyamoya disease (MMD) is a rare disorder of the cerebrovascular system. It steno‐occlusive that involves angiogenesis and blood–brain barrier (BBB) disruption. Bradykinin (BK), its metabolite des‐Arg9‐BK, receptor (B1R) affect BBB integrity. In this study, we aimed to investigate changes in BK, B1R des‐Arg9‐BK levels serum brain tissues patients with MMD explore underlying mechanism these markers MMD. We obtained samples superficial temporal artery (STA) tissue from Department...
Implant particles may induce inflammatory response by activating the nuclear factor kappaB (NFkappaB) and mitogen activated protein kinases (MAPK). Previous studies have shown that these signaling pathways are involved in transforming growth factor-beta kinase 1 (TAK1) cascades induced receptor activator of NFkappaB ligand (RANKL) tumor necrosis factor-alpha (TNF-alpha) as well interleukin-1beta (IL-1beta). In this study, roles TAK1 pathway production pro-inflammatory cytokine TNF-alpha RAW...
A cross-leg or cross-bridge free flap is one of the choices for reconstruction serious leg soft tissue defects. Here, we report on six cases and foot with a distally based extended peroneal artery septocutaneous perforator without microvascular anastomoses. The vascular pedicle includes artery, its branch, concomitant veins. total length ranges from 10 to 14 cm, size 18 x 8 21 cm. All flaps survived completely complications. Compared flap, anastomoses does not require use some instruments...
A 35-year-old man presenting with right-sided total hand skin degloving injury due to crushing of printing machine was reported in this study. The superficial vein forearm transplanted intraoperatively reconstruct the blood supply, and avulsed replanted situ. patient followed-up for 2 years, satisfactory results functional recovery were achieved.
A cross-leg or cross-bridge free flap is frequently used for the reconstruction of leg defects in cases with no suitable recipient vessels vicinity defect. Here we report eight a distally based posterior tibial artery without microvascular anastomosis technology. was elevated and to reconstruct contralateral defects. skin incision made near wound create bridge, subcutaneous tunnel between vascular pedicle pass over. All flaps survived completely complications, except case minor erosion donor...
BackgroundThe elbow joint is sensitive to trauma from accidents, sports injuries, and surgical trauma. Some patients develop ossification or contracture of the medial collateral ligament (MCL) after A less invasive reconstruction MCL can be performed resection diseased MCL. The biomechanical characteristics this technique have been demonstrated validated. However, its clinical effectiveness safety require further confirmation in practice.MethodsThis open-label, non-randomised, prospective,...
<title>Abstract</title> Copper, an essential trace element, is indispensable for the growth and physiological functions of living beings, influencing several critical processes like cellular energy production, antioxidant defense, communication within cells, functioning enzymes. However, when copper levels exceed normal limits, it can lead to significant health issues. Recent investigations into adverse effects have shed light on its toxicological impacts, particularly focusing metabolic...