A5100325825- Animal Virus Infections Studies
- Virus-based gene therapy research
- Viral gastroenteritis research and epidemiology
- Animal Nutrition and Physiology
- Herpesvirus Infections and Treatments
- Meat and Animal Product Quality
- Nutrition, Genetics, and Disease
- Viral Infections and Vectors
- interferon and immune responses
- Pharmacological Receptor Mechanisms and Effects
- Food Quality and Safety Studies
- Biochemical effects in animals
- Neuropeptides and Animal Physiology
- Legume Nitrogen Fixing Symbiosis
- Effects of Environmental Stressors on Livestock
- Gut microbiota and health
- Viral Infections and Immunology Research
- Moringa oleifera research and applications
- Pharmacological Effects and Assays
- Consumer Attitudes and Food Labeling
- Nutritional Studies and Diet
- GABA and Rice Research
- Probiotics and Fermented Foods
- Animal Disease Management and Epidemiology
Zhongshan People's Hospital
2024
Sichuan Agricultural University
2019-2022
Shanghai Ninth People's Hospital
2017
Shanghai Jiao Tong University
2017
Huazhong Agricultural University
2016
University of California, San Francisco
2015
This study was conducted to investigate the effects of different oligosaccharides on growth performance and intestinal function in broilers.A total 360 1-day-old yellow-feather chickens were randomly divided into 5 groups fed with a basal diet supplemented 50 mg/kg chlortetracycline (ANT), 3 g/kg isomalto-oligosaccharide (IMO), raffinose oligosaccharide (RFO), 30 chitooligosaccharide (COS). The experiment lasted for 56 days, 1-28 days as starter phase 29-56 grower phase.The results showed...
Abstract It has been well characterized that the neonatal Fc receptor (FcRn) transports maternal IgG to a fetus or newborn and protects from degradation. We previously reported FcRn is expressed in model of normal porcine intestinal epithelial cells (IPEC-J2). Transmissible gastroenteritis an acute enteric disease swine caused by transmissible virus (TGEV). How (pFcRn) expression regulated pathogenic infection remains unknown. Our research shows IPEC-J2 infected with TGEV had up-regulated...
SummaryBackground & aimsPrevious observational studies have yielded inconsistent findings regarding associations between red/processed meat intake and the risk of cardiovascular disease (CVD). Some suggested positive relationships, while others demonstrated no significant associations. However, causal effects remain uncertain. This 2023 Mendelianrandomization (MR) study investigated relationship red processed (porkmeat, mutton meat, beef meat)intake CVD by analyzing summary data from UK...
Senecavirus A (SVA) is a new type of virus related to swine vesicular disease, which results in enormous economic losses worldwide. At present, the host transcriptional responses SVA infection, host-SVA interactions, and mechanism innate immune modulation are not well understood. This study explores gene expression profiles PK-15 cells at 0, 6, 12, 18, 24, 36 h post-infection by RNA sequencing. Our analysis identified 61, 510, 1,584, 2,460, 2,359 differentially expressed genes (DEGs)...
Abstract Porcine epidemic diarrhoea virus (PEDV) belongs to the family Coronavirus, a genus of coronavirus, highly contact‐infectious intestinal disease pathogen. In this study, we downloaded 62 PEDV S gene sequences uploaded GenBank, including 10 by our laboratory from 2018, and constructed evolution tree using MEGA V7.0 software. Phylogenetic analysis indicated that genogroup in Sichuan Province was divided into three coexisting genogroups (GII‐a, GII‐b GI‐a), them, GII‐a has become main...
Opioid receptors belong to the large superfamily of seven transmembrane-spanning (7TM) G protein-coupled (GPCRs). As a class, GPCRs are fundamental physiological importance mediating actions majority known neurotransmitters and hormones. The Mu, Delta, Kappa (MOP, DOP, KOP) opioid particularly intriguing members this receptor family as they targets involved in many neurobiological diseases such addiction, pain, stress, anxiety, depression. Recently we discovered that aaptamine class marine...
Abstract Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus. At present, it has been treated by various ways, including vaccination of inactivated vaccine, attenuated live subunit etc., but the control PRRSV infection still inadequate Therefore, necessary to study new drugs against infection. In this study, antiviral effect SR on in vitro was studied.Results: significantly inhibited pretreated cells. addition, results also showed that adhesion, entry...
Abstract Background: Porcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus. Currently, it treated in various ways, including vaccination with inactivated vaccine, live attenuated or subunit but the control of PRRSV infection still inadequate. Therefore, necessary to study new drugs against infection. In this study, antiviral effect 1-calcium phosphonate uracil on vitro was studied. Results: significantly inhibited SR pretreated cells. addition, results showed that...