- Hydrogels: synthesis, properties, applications
- Molecular Sensors and Ion Detection
- Electrochemical sensors and biosensors
- MicroRNA in disease regulation
- Electrospun Nanofibers in Biomedical Applications
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
- Drug Solubulity and Delivery Systems
- Psoriasis: Treatment and Pathogenesis
- Advanced Sensor and Energy Harvesting Materials
- Analytical chemistry methods development
- Circular RNAs in diseases
- Advancements in Transdermal Drug Delivery
- Lanthanide and Transition Metal Complexes
- Wnt/β-catenin signaling in development and cancer
- Nosocomial Infections in ICU
- Dermatology and Skin Diseases
- Advanced Drug Delivery Systems
- Advanced Materials and Mechanics
- Analytical Methods in Pharmaceuticals
- Cancer-related Molecular Pathways
- Berberine and alkaloids research
- Cancer-related molecular mechanisms research
- Polymer composites and self-healing
Heilongjiang University of Chinese Medicine
2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2017-2023
Wenzhou Medical University
2017-2023
Jiamusi University
2018-2023
Beijing Normal University
2018
Jining First People's Hospital
2018
Fabrication of hydrogels with unique microstructures and better mechanical properties through the self-assembly commercially available synthetic polymers small molecules is great scientific practical importance. A type physical prepared by polyvinyl alcohol (PVA) tannic acid (TA) in aqueous solution a low PVA-TA concentration (0.5-6.0 wt %) at room temperature. With increase concentration, water content increases, TA decreases from 23.1 to 6.4%. The driving force for proven be hydrogen...
The frequency of antimicrobial resistance has increased globally due to misuse and overuse antibiotics, multi-drug resistant (MDR) bacteria are now recognized as a major cause hospital-acquired infections (HAI). Our aim was investigate the prevalence, distribution, susceptibility rates MDR in patients with HAI from tertiary hospital China. We retrospectively evaluated all confirmed diagnosis bacterial infection at general Jining, for period between January 2012 December 2014. following...
Shape memory hydrogels (SMHs) have a wide range of potential practical applications. However, the mechanically weak and soft nature most SMHs strongly impedes their Here, we report novel kind thermal-responsive SMH with high tensile strength elastic moduli. Organogels are first prepared by copolymerization hydrophilic monomer N-vinylpyrrolidone (NVP) hydrophobic acryloxy acetophenone (AAP) in N,N′-dimethylformamide (DMF) solutions, then, poly(vinylpyrrolidone-co-acryloxy acetophenone)...
Polymer-based drug-controlled release systems offer greater efficacy and potency than conventional therapies. However, prominent drug side effects, lower circulation, low loading capabilities limit their application range. In this work, the combination of Simvastatin (SIV) Carvacrol (CAV) into PEG-PLGA microspheres (SIV-CAV-PP-MS) was achieved via an emulsification-solvent evaporation technique, resulting in characterized by high encapsulation efficiency reduced particle size. vitro studies...
Breast cancer is the most prevalent and leading cause of cancer‑associated mortalities among women worldwide today. Accumulating evidence suggested that miR‑372 may serve important roles in initiation development various human cancers. However, role breast remains unknown. The present study demonstrated expression level tissues cell lines significantly reduced compared with normal lines. Furthermore, results functional assays indicated inhibits proliferation induces apoptosis MCF‑7 line....
The goal of the current study was to explore potential benefits Tretinoin (Tre) fatty acid vesicles (Tre-FAV) as a prospective antipsoriatic topical delivery system. This promising system can counteract drug challenges in terms its extremely low aqueous solubility, instability, skin irritation, and serious systemic adverse effects. Tre-loaded were successfully developed entirely characterised. selected formulation investigated for vitro release, ex vivo retention psoriasis efficacy studies....
Phenylketonuria(PKU) is a kind of genetic and metabolic disease which caused by mutations. High concent phenylalanine its metabolites in the blood result impairment brain development, even mental retardation. In recent years, due to impact factors diet environment, PKU was significantly increased. Studies have shown that early detection abnormal levels treatment will greatly reduce rate Therefore, monitoring particularly important for phenylketonuria patients. This study discussed new method...
Abstract This paper proposes a simpler and operable method to replace the traditional detection detect mercury ion in water samples quickly easily. Firstly, rhodamine derivatives are synthetised, then derivative fluorescent molecular probe is constructed adopted ions samples. In order aqueous solutions, fluorescence spectroscopy was this experiment, were used as probes. The its corresponding solutions. Different metal different chlorides added solution of compound. Only one with addition...