A5007603805- Respiratory Support and Mechanisms
- Systemic Sclerosis and Related Diseases
- Acute Kidney Injury Research
- Mechanical Circulatory Support Devices
- Nosocomial Infections in ICU
- Traumatic Brain Injury and Neurovascular Disturbances
- Sepsis Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Poisoning and overdose treatments
- Intensive Care Unit Cognitive Disorders
- Connective tissue disorders research
- Adrenal Hormones and Disorders
- Analytic Number Theory Research
- Central Venous Catheters and Hemodialysis
- Microbial Inactivation Methods
- Dialysis and Renal Disease Management
- Cardiovascular Health and Disease Prevention
- Dermatologic Treatments and Research
- Coleoptera Taxonomy and Distribution
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Ischemia and Reperfusion
- Aortic aneurysm repair treatments
- Congenital heart defects research
- Algebraic Geometry and Number Theory
- Cannabis and Cannabinoid Research
Kyoto Medical Center
2019-2025
Kyoto University
2021-2024
Saiseikai Kumamoto Hospital
2017-2021
Kanazawa University
2008
Pennsylvania State University
2001
Tokyo Women's Medical University Hospital
1997
Background Arterial stiffness is an important predictor of cardiovascular events; however, indexes for measuring arterial have not been widely incorporated into routine clinical practice. This study aimed to determine whether the cardio-ankle vascular index (CAVI), based on blood pressure-independent parameter β and reflecting from origin ascending aorta, a good events in patients with disease risk factors large prospective cohort. Methods Results multicenter cohort study, commencing May...
Objective To determine levels of serum soluble OX40 (also termed CD134, a member the tumor necrosis factor receptor superfamily) and their clinical associations in patients with systemic sclerosis (SSc). Methods Serum were examined by ELISA 53 SSc, 15 lupus erythematosus (SLE), 32 healthy individuals. Results significantly elevated SSc (125.7 ± 5.7 pg/ml) compared to SLE (80.7 1.7 pg/ml; p < 0.005) controls (88.2 3.0 0.0001). Elevated found be associated disease duration less than 2 years...
Abstract Background The lack of precise information on the epidemiology peripheral intravascular catheter (PIVC)-related phlebitis and complications in critically ill patients results absence appropriate preventive measures. Therefore, we aimed to describe use PIVCs incidence/occurrence intensive care unit (ICU). Methods This prospective multicenter cohort study was conducted 23 ICUs Japan. All consecutive aged ≥ 18 years admitted ICU were enrolled. inserted prior admission those newly after...
Objectives The Clinical Practice Guidelines for the Management of Sepsis and Septic Shock weakly recommend steroids septic shock resistant to fluid resuscitation vasopressors. This study aimed describe clinical practices in real world compare association between intermittent or continuous infusion prognosis.
Cetuximab is a chimeric human-murine monoclonal antibody that binds competitively and with high affinity to the epidermal growth factor receptor (EGFR) used treat advanced squamous cell carcinoma of head neck. After receiving total six doses cetuximab, 72-year-old male presented pretibial edema, acne-like skin rash, nephrotic syndrome. The renal biopsy findings revealed features thrombotic microangiopathy (TMA), expansion subendothelial zone, reduplication glomerular basement, swelling...
Fluid creep, including fluids administered as drug diluents and for the maintenance of catheter patency, is major source fluid intake in critically ill patients. Although hypoxemia may lead to restriction, epidemiology creep patients with unclear. This study aimed address burden due among respiratory support according oxygenation status.We conducted a post-hoc analysis prospective multicenter cohort 23 intensive care units (ICUs) Japan from January March 2018. Consecutive adult who underwent...
Abstract Aim The overdose of caffeine, a cytochrome P450 1A2 probe, in young women has become problem. aim this study was to evaluate possible drug interactions between intentionally overdosed caffeine (12 g) and oral contraceptive doses ethinyl estradiol prescribed woman suicide attempt. Methods serum concentrations the patient time‐dependent inhibition oxidation vitro were evaluated. Results concentration 4 h after 136 μg/mL; from data obtained 28 overdose, half‐life estimated be 33 h,...