- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Transplantation: Methods and Outcomes
- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Tissue Engineering and Regenerative Medicine
- Diversity and Career in Medicine
- Organ Transplantation Techniques and Outcomes
- Cardiac pacing and defibrillation studies
- Surgical Simulation and Training
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Renal Transplantation Outcomes and Treatments
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Electrospun Nanofibers in Biomedical Applications
- Venous Thromboembolism Diagnosis and Management
- Fuel Cells and Related Materials
- Tracheal and airway disorders
- Anatomy and Medical Technology
- Coronary Artery Anomalies
Thomas Jefferson University
2017-2025
Thomas Jefferson University Hospital
2018-2024
Jefferson University Hospitals
2020-2024
Lankenau Medical Center
2022
University of Rochester
2015-2021
Johns Hopkins University
2021
University of Colorado Denver
2021
University of British Columbia
2021
University of Michigan
2021
University of Pennsylvania
2021
Continuous-flow left ventricular assist devices (CF-LVADs) have revolutionized the management of patients with advanced heart failure. Alternative implant strategies are increasingly used for device placement. We reviewed our experience from Mechanical Circulatory Support Research Network registry HeartWare centrifugal CF-LVAD (HVAD). From May 2004 to August 2015, 1,150 underwent primary implantation at institutions. Within this group, a total 283 (25%) were implanted HVAD. A minimally...
Cannulation-related complications are a known source of morbidity in patients supported on veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Despite its prevalence, little is regarding the outcomes who suffer such complications. This single institution review cannulation-related and effect mortality VA-ECMO from January 2010-2015 using three cannulation strategies: axillary, femoral, central. Complications were defined as advanced if they required major interventions (fasciotomy,...
Ventricular assist devices (VADs) are not fully biocompatible, and therefore predisposed to device thrombosis subsequent pump dysfunction. Clinically significant hemolysis in VADs most often occurs as a result of thrombosis, but can also be caused by other factors. Herein we describe the evaluation management VAD hemolysis.
ABSTRACT Background Safe and effective pediatric blood pumps continue to lag far behind those developed for adults. To address this growing unmet clinical need, we are developing a hybrid, continuous‐flow, magnetically levitated, total artificial heart (TAH). Our hybrid TAH design, the Dragon Heart (DH), integrates both an axial flow centrifugal pump within single, compact housing. The is embedded in central hub region of pump, rotate around common axis, while maintaining separate fluid...
Background: Data are lacking to guide standardized management of coronary artery aneurysms (CAA). We sought analyze the available evidence in a quantitative manner. Methods: Electronic search identified 431 case reports or series on CAA, comprising 488 patients. Patient-level data were extracted. Subgroups with (CAAF) and without fistulous connections (CAAO) analyzed separately. Results: Fistulous connection was present 24.0% (117/488) patients CAA. Angina presenting symptom 64.7% (301/465),...
ABSTRACT Background Predicted heart mass (PHM) ratio is a commonly used metric for donor‐to‐recipient size matching that has been associated with survival after transplantation (HTx). PHM represents sum of two separate statistical models predicted left ventricular (PLVM) and right (PRVM); however, their individual contributions have not sufficiently studied. We sought to assess the association PLVM (PLVMR) PRVM ratios (PRVMR) overall posttransplant individually. Methods Adult transplant...
ABSTRACT Background We sought to characterize adaptive changes the revised UNOS donor heart allocation policy in 2018 and estimate long‐term survival trends for transplant (HTx) recipients with respect inotropic support. Methods Patients listed HTx between July 18, 2014, 2016 (prepolicy revision) October 2018, 2020 (postpolicy were identified from database. Sub‐analyses examined device progression where patients on inotropes later transplanted and/or extracorporeal membranous oxygenator...
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Diabetes mellitus (DM) is a risk factor for morbidity and mortality in patients with heart failure. The effect of DM on post-left ventricular assist device (LVAD) implantation outcomes unclear. This study sought to investigate whether had worse than without after LVAD support resulted better control DM.We retrospectively reviewed 341 consecutive adults who underwent from 2007 2016. Patient characteristics adverse events were studied compared between DM. One hundred thirty-one (38%) Compared...