Davide Menafra

ORCID: 0000-0002-4403-6801
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About
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Research Areas
  • Ovarian function and disorders
  • Hormonal and reproductive studies
  • Sexual Differentiation and Disorders
  • Growth Hormone and Insulin-like Growth Factors
  • Sperm and Testicular Function
  • Diet and metabolism studies
  • Pituitary Gland Disorders and Treatments
  • Sexual function and dysfunction studies
  • Pharmacology and Obesity Treatment
  • Renal and related cancers
  • Adrenal Hormones and Disorders
  • Adrenal and Paraganglionic Tumors
  • Effects and risks of endocrine disrupting chemicals
  • Hypothalamic control of reproductive hormones
  • Reproductive Biology and Fertility
  • Heavy Metal Exposure and Toxicity
  • Gut microbiota and health
  • Menopause: Health Impacts and Treatments
  • Pharmacological Effects and Assays
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Impact of Light on Environment and Health
  • Vitamin D Research Studies
  • COVID-19 Clinical Research Studies
  • Muscle metabolism and nutrition
  • Peroxisome Proliferator-Activated Receptors

University of Naples Federico II
2017-2024

Federico II University Hospital
2016-2020

Abstract Context Fertility represents a major concern in patients with acromegaly. Objective The current retrospective study aimed to investigate gonadal function and fertility rates acromegalic women. Methods In this referral-center study, 50 women disease onset within reproductive age were evaluated for prevalence of dysfunction infertility. Anthropometric, metabolic, hormonal parameters, gynecological ultrasound at diagnosis after control. Data about menstrual disturbances, pregnancy,...

10.1210/clinem/dgad042 article EN The Journal of Clinical Endocrinology & Metabolism 2023-02-15

Female sexual dysfunction (FSD) may be a mirror of poor cardiometabolic state. In small pilot study enrolling 71 women with FSD, we previously demonstrated that clitoral Pulsatility Index (PI) evaluated by using color Doppler ultrasound (CDU), reflecting vascular resistance, was associated risk factors. Data on uterine CDU in this context are lacking. First, to confirm reported data the direct association between PI and factors larger population consulting for symptoms; second, investigate...

10.1038/s41598-021-98336-7 article EN cc-by Scientific Reports 2021-09-22

The current randomized, double-blind, placebo-controlled clinical trial addressed the effects on penile erectile function of relatively high daily oral doses (6 g/day) L-ARG for 3 months (N = 51) compared to placebo 47), in patients with vasculogenic ED, comparison between mild-moderate and severe ED.The outcome measures included IIEF-6 score cavernous arteries peak systolic flow velocity (PSV) at dynamic duplex ultrasonography (PDU).L-ARG supplementation significantly increased overall...

10.1007/s40618-021-01704-3 article EN cc-by Journal of Endocrinological Investigation 2022-01-01

Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21-OHD) represents the most frequent form of CAH and 46, XX disorder sex development in female newborns. In majority cases, particularly developed countries, patients suffering from classic forms reach diagnosis at birth or early childhood, allowing a prompt treatment with correct gender assignment. The current manuscript describes an unusual case Italian 46-year-old woman, homeborn 60s, receiving extraordinarily late...

10.3389/fgene.2022.902844 article EN cc-by Frontiers in Genetics 2022-10-31

Abstract Background An observational study involving patients recovered from COVID-19 was conducted in order to evaluate the presence/absence of vein wall thickness increasing, according severity pulmonary involvement quantified with a CT-scoring system. Methods The venous (VWT) 31 (23 males and 8 females) COVID 19 previously admitted Federico II University Hospital Naples evaluated through ultrasound measurement common femoral Vein 1 cm proximal saphenous-femoral junction popliteal distal...

10.1186/s12967-024-04857-w article EN cc-by Journal of Translational Medicine 2024-01-17
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