Ignatius Alvarez Cooper

ORCID: 0000-0002-4426-9963
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About
Contact & Profiles
Research Areas
  • Biochemical Analysis and Sensing Techniques
  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Regulation of Appetite and Obesity
  • Tryptophan and brain disorders
  • Diet, Metabolism, and Disease
  • Treatment of Major Depression
  • Birth, Development, and Health
  • Neurogenesis and neuroplasticity mechanisms
  • Diet and metabolism studies
  • Neurotransmitter Receptor Influence on Behavior

Queensland University of Technology
2020-2024

Translational Research Institute
2020-2021

Sugar has become embedded in modern food and beverages. This led to overconsumption of sugar children, adolescents, adults, with more than 60 countries consuming four times (>100 g/person/day) the WHO recommendations (25 g/person/day). Recent evidence suggests that obesity impulsivity from poor dietary habits leads further processed The long-term effects on cognitive processes hyperactivity overconsumption, beginning at adolescence are not known. Using a well-validated mouse model...

10.3389/fnins.2021.670430 article EN cc-by Frontiers in Neuroscience 2021-06-07

Abstract While the dire cardiometabolic consequences of hypercaloric modern ‘Western’ diet are well known, there is not much information on health impact a high sucrose inducing weight gain. Here, we tested hypothesis that rats reared with intermittent binge access to in addition normal chow would develop an inflammatory response brain. To test this hypothesis, undertook serial PET/MRI scans TSPO ligand [ 18 F]DPA714 group (n=9) at baseline and again after voluntarily consuming 5% solution...

10.1038/s41598-021-90817-z article EN cc-by Scientific Reports 2021-05-27

Neuroscience offers important insights into the pathogenesis and treatment of obesity by investigating neural circuits underpinning appetite feeding. Gamma-aminobutyric acid (GABA), one most abundant neurotransmitters in brain, its associated receptors represent an array pharmacologically targetable mediators signalling. Targeting GABAergic system is therefore increasingly investigated approach to treatment. However, many projections that control feeding have yet be collectively analysed....

10.1016/j.neubiorev.2024.105743 article EN cc-by Neuroscience & Biobehavioral Reviews 2024-05-29
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