A5075023268- Neuroblastoma Research and Treatments
- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Sarcoma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Congenital Diaphragmatic Hernia Studies
- Lymphoma Diagnosis and Treatment
- Tumors and Oncological Cases
- Testicular diseases and treatments
- Cancer, Hypoxia, and Metabolism
- Soft tissue tumor case studies
- Multiple and Secondary Primary Cancers
- Renal and related cancers
- Myasthenia Gravis and Thymoma
- Neurofibromatosis and Schwannoma Cases
- Glioma Diagnosis and Treatment
- Hedgehog Signaling Pathway Studies
- Tracheal and airway disorders
- Ovarian cancer diagnosis and treatment
- Pancreatic and Hepatic Oncology Research
- Urologic and reproductive health conditions
- Metabolomics and Mass Spectrometry Studies
- Neonatal Health and Biochemistry
- Vascular Tumors and Angiosarcomas
- Ethics and Legal Issues in Pediatric Healthcare
Gdańsk Medical University
2013-2023
Weatherford College
2014
Palmetto Hematology Oncology
2010
University of Bydgoszcz
2008
University of Wrocław
2008
Medical University of Lublin
2008
Children's Memorial Health Institute
2008
Centrum Onkologii
2008
The low incidence and the heterogeneity of very rare tumors (VRTs) demand for international cooperation. In 2008, EXPeRT (European Cooperative Study Group Pediatric Rare Tumors) was founded by national groups from Italy, France, United Kingdom, Poland Germany. first aims were to agree on a uniform definition VRTs develop currently most relevant scientific questions. Current initiatives include data exchange, retrospective prospective studies specific entities, development harmonized...
Adrenocortical tumours (ACTs) are rare during childhood. A complete surgical resection provides the best chance of cure, but role and efficacy adjuvant therapy still controversial. Various histologic criteria malignancy for ACTs adopted in children do not facilitate comparative studies completely shared. Therefore, a sharp demarcation between benign malignant lesions has been recognised, making it difficult to identify who potentially needs perioperative therapy. This manuscript presents...
Pleuropulmonary blastoma (PPB) is a rare cancer occurring mainly during early childhood and often associated with germline DICER1 mutations. It classified by the macroscopic appearance into three interrelated clinico-pathologic entities on developmental continuum. Complete tumor resection main prognostic factor can be performed at diagnosis or after neoadjuvant treatment that includes chemotherapy in some cases radiotherapy. Optimal modalities of neo- adjuvant treatments challenging taking...
Cutaneous melanoma is rare in childhood and published studies have mainly been retrospective single-institution series or small case series. Given the absence of clinical protocols dedicated to pediatric melanoma, treatment approach generally extrapolated from ones applied adults.Coordinated by European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT), this study collected patients prospectively registered between 2002 2012 under national cooperative projects tumors Italy, Poland,...
Abstract It has become increasingly clear in recent years that we need to develop ad hoc strategies combat very rare tumors (VRT) of pediatric age. In 2008, several schemes being run different countries were pooled together create the European Cooperative Study Group for Pediatric Rare Tumors (EXPeRT) project: a cooperative study group aimed promote research relatively uncharted territory EXPeRT members able activate levels cooperation achieve their goals, and obtain dedicated funding by...
In the last 40 years, considerable progress was made in treatment of childhood cancer. Nearly 80% children achieve long-term clinical remission or are permanently cured. This improvement is however not without sacrifice. first Polish study analyzing general health status and epidemiology organ late effects cohort adolescent cancer survivors monitored by doctors registered on-line national database for (N = 1761). tool collects information on previous therapy current (medical history,...
Salivary gland carcinomas (SGCs) are rare during childhood and adolescence. Consequently, no standardized recommendations for the diagnosis therapeutic management of pediatric SGC available, oncologists surgeons generally follow adult guidelines. Complete surgical resection with adequate margins constitutes cornerstone treatment. However, indications modalities adjuvant therapy remain controversial may be challenging in view potential long-term toxicities population. This paper presents...
Abstract The PARTNER project (Paediatric Rare Tumours Network ‐ European Registry) was launched in 2016. aims to create a Registry dedicated children and adolescents with very rare tumors (VRT). It links existing national registries provides registry for those countries which VRT has not yet been created. This consortium is composed of the various cooperative groups their respective member institutions. strategic value this based on Europe‐wide data collection concerning treatment VRTs....
Abstract Cutaneous melanoma is rare in children and, like other very pediatric tumors, it suffers from a shortage of knowledge and clinical expertise. The management often challenging. Its pathological diagnosis may be difficult, there no standard treatment. In the absence specific treatment guidelines, young patients are generally treated following same principle as for adults, but concern remains about their access to trials new drugs, which have been shown dramatically change natural...
Abstract Pancreatoblastoma (PBL) is a rare malignant epithelial neoplasm that affects typically young children. Signs related to advanced upper‐abdominal tumor accompanied by elevated serum α‐fetoprotein levels in child suggest PBL, however histopathological confirmation mandatory. The mainstay of the treatment complete surgical resection. Unresectable and/or metastatic PBL may become amenable delayed surgery after neoadjuvant chemotherapy. This manuscript presents international consensus...
Abstract As part of the European Union‐funded project designated Paediatric Rare Tumours Network ‐ Registry (PARTNER), Cooperative Study Group for Pediatric Tumors (EXPeRT) is continuously developing consensus recommendations in order to harmonize standard care very rare solid tumors children and adolescents. This paper presents internationally recognized diagnosis treatment sex cord stromal (SCST). The clinical approach testis (TSCST) ovary (OSCST) depends on histological differentiation...
Angiosarcoma in children - still uncontrollable oncological problem. The report of the Polish Paediatric Rare Tumours StudyAngiosarcoma is a rare, highly malignant vascular neoplasm with little data available on its clinical course and management children. Ten angiosarcoma (M/F: 6/4; aged 2, 3-16 years) registered Soft Tissue Sarcomas Studies between 1992 2006. Primary tumour exceeded 5 cm seven patients affected mainly deep tissues (heart-2, head/neck, bladder, brain, liver upper limb one...
Abstract Nasopharyngeal carcinoma (NPC) is a rare pediatric tumor. Collaborative studies performed over the last decades showed improved results compared to historical data, but standardized guidelines for diagnosis and management of NPC are still unavailable. This study presents European consensus guideline treatment developed by Cooperative Study Group Pediatric Rare Tumors (EXPeRT). Main recommendations include induction chemotherapy with cisplatin 5‐flurouracil, concomitant...
Abstract In this study, the levels of ischemia‐modified albumin (IMA) in pediatric oncology patients with soft tissue sarcomas (STSs) and neuroblastoma (NB) were analyzed. To date, there have been no studies concerning IMA these groups patients. Ninety‐nine children STSs NB analyzed from 2006 to 2009, 30 healthy also enrolled study. measured throughout treatment all The cancer (mean 116.8±39.3 U/ml), 119.8±27.5 114.6±36.6 U/ml) significantly higher than control 87.3±38.3 U/ml; P =0.0013,...
Pediatric hemangiopericytoma (HPC) is an extremely rare vascular tumor with little data available on its clinical course and management.Fourteen children HPC registered in Polish Rare Tumors Soft-tissue Sarcomas Studies between 1992 2002 are reported.Seven patients (F/M: 5/2, age 2-10 months) had infantile HPC, four of whom primary tumors affecting superficial tissues the trunk upper limbs. No child initial nodal or organ metastases. Primary excision (PE) was performed only three lesions....
Invasive thymomas and thymic carcinomas are rare tumors jointly accounting between 0.2% 1.5% of malignancies in adults. They usually at an advanced stage when diagnosed have both high recurrence poor survival rates. In this report, the aim is to explore our experience treatment Polish children.The clinical data nine children with carcinomas, treated 1992 2008 oncological surgical centers was retrospectively analyzed.In five cases, presenting symptoms resulted from compression respiratory...
Introduction: The improvements made in the field of pediatric oncology last decades due to propensity develop national and international cooperative protocols have not been historically seen for a number very rare neoplasms whose common denominator lies their having treated as orphan diseases. For several years now, this situation has fortunately gradually changing, various projects dedicated these diseases developed countries.Areas covered: This paper describes schemes tumors countries with...