A5001887115- Cancer Immunotherapy and Biomarkers
- Cutaneous Melanoma Detection and Management
- Immunotherapy and Immune Responses
- CAR-T cell therapy research
- Melanoma and MAPK Pathways
- COVID-19 and healthcare impacts
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Pancreatic and Hepatic Oncology Research
- Economic and Financial Impacts of Cancer
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Uterine Myomas and Treatments
- Colorectal Cancer Treatments and Studies
- Lymphoma Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Brain Metastases and Treatment
- COVID-19 Clinical Research Studies
- Glioma Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Childhood Cancer Survivors' Quality of Life
- Endometriosis Research and Treatment
Fondazione IRCCS Istituto Nazionale dei Tumori
2013-2025
Ospedale di Circolo e Fondazione Macchi
2021-2024
University of Insubria
2021-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2020-2023
Aziende Socio Sanitarie Territoriale dei Sette Laghi
2022
GTx (United States)
2021
Ospedale Maggiore
2021
Ospedale Papa Giovanni XXIII
2019-2020
Palmetto Hematology Oncology
2020
Istituti di Ricovero e Cura a Carattere Scientifico
2015-2019
The novel severe acute respiratory syndrome coronavirus-2 pandemic is a global health problem, which started to affect China by the end of 2019. In Europe, Italy has faced this disease entity (named coronavirus [COVID-19]) first and severely. COVID-19 represents significant hurdle for public services potential harm patients with cancer. Collegio Italiano dei Primari Oncologi Medici (CIPOMO) an Italian association head physicians in oncology departments, promotes working research activities...
COVID-19 has disrupted the global health care system since March 2020. Lung cancer (LC) patients (pts) represent a vulnerable population highly affected by pandemic. This multicenter Italian study aimed to evaluate whether outbreak had an impact on access diagnosis and treatment of LC pts compared with pre-pandemic time.Consecutive newly diagnosed referred 25 Oncology Departments between December 2020 were included. Access rate temporal intervals date symptoms onset diagnostic therapeutic...
Ipilimumab plus nivolumab (COMBO) is the standard treatment in asymptomatic patients with melanoma brain metastases (MBM). We report a retrospective study aiming to assess outcome of MBM treated COMBO outside clinical trials.
Background Obesity is a risk factor for malignancy; however, its prognostic role in patients with metastatic melanoma controversial. We aim to investigate the of body mass index (BMI) receiving mitogen-activated pathway kinase inhibitors (MAPKi), immune checkpoint (ICIs) alone or their sequence. Methods Data on ≥1 line systemic treatment were retrieved from prospectively collected databases. Progression-free survival (PFS) and overall (OS) analyzed by means multivariable stratified Cox...
immunotherapy with immune checkpoint inhibitors has become one of the standard therapeutic modalities for patients advanced melanoma. Melanoma female lower genital tract is a rare and aggressive disease, poor long-term clinical outcomes. To date, no study evaluated role in metastatic melanoma tract.Data women were prospectively collected. Survival outcomes over time was assessed using Kaplan-Meier model.Seven cases (vulva [n=2], vagina [n=4], uterine cervix [n=1]) treated are reviewed. Two...
Data on the efficacy and safety of anti PD-1 antibodies in children adolescents (CA) with melanoma are lacking. The aim this study was to determine outcomes CA patients receiving antibodies.
Data on BRAF/MEK inhibitors in pediatric and adolescent melanoma patients are limited. We report data of treated with dabrafenib/trametinib for compassionate use at our institution. From January 2020, four Stage III two IV disease were treated. Our demonstrates that targeted therapy children adolescents is safe achieves survival rates comparable to those observed adults. These findings support granting young adult-onset tumors access use, as well increasing their inclusion clinical trials....
Objective The aim of the study was to evaluate surgical management and role different prognostic factors on survival outcomes women affected by genital (i.e., vulvar vaginal) melanoma. Materials Methods Data patients undergoing primary treatment for melanoma were evaluated in this retrospective study. Baseline, pathological, postoperative variables tested identify factors. Five-year disease-free (DFS) overall (OS) analyzed using Kaplan-Meier Cox proportional hazards models. Results Overall,...