Daxian Zhao

ORCID: 0000-0002-4473-2241
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About
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Research Areas
  • Invertebrate Immune Response Mechanisms
  • Aquaculture disease management and microbiota
  • Influenza Virus Research Studies
  • Physiological and biochemical adaptations
  • Aquaculture Nutrition and Growth
  • Immune Response and Inflammation
  • Neurobiology and Insect Physiology Research
  • Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
  • Fish Ecology and Management Studies
  • Viral gastroenteritis research and epidemiology
  • Crustacean biology and ecology
  • Antimicrobial Peptides and Activities
  • Insect Utilization and Effects
  • Escherichia coli research studies
  • Protein Hydrolysis and Bioactive Peptides
  • MicroRNA in disease regulation
  • Aquatic Invertebrate Ecology and Behavior
  • Biochemical effects in animals
  • Vector-borne infectious diseases
  • Insect symbiosis and bacterial influences
  • Marine and fisheries research
  • Genomics, phytochemicals, and oxidative stress
  • Zebrafish Biomedical Research Applications
  • Fish Biology and Ecology Studies
  • Consumer Attitudes and Food Labeling

Nanchang University
2009-2024

State Key Laboratory of Food Science and Technology
2010-2013

University of Florida
2013

East China Normal University
2008-2011

Ningxia University
2011

The Betta fish displays a remarkable variety of phenotypes selected during domestication. However, the genetic basis underlying these traits remains largely unexplored. Here, we report high-quality genome assembly and resequencing 727 individuals representing diverse morphotypes fish. We show that current breeds have complex domestication history with extensive introgression wild species. Using genome-wide association study, identify multiple traits, including coloration patterns, "Dumbo"...

10.1126/sciadv.abm4955 article EN cc-by-nc Science Advances 2022-09-21

Current influenza vaccines need to be annually reformulated well match the predicated circulating strains. Thus, it is critical for developing a novel universal vaccine that would able confer cross-protection against constantly emerging divergent virus Influenza A genus of Orthomyxoviridae family viruses. nucleoprotein (NP) structural protein which encapsidates negative strand viral RNA, and anti-NP antibodies play role in cross-protective immunity. Lactococcus lactis (L. lactis) an ideal...

10.1186/s12934-015-0287-4 article EN cc-by Microbial Cell Factories 2015-08-04

Development of safe and effective vaccines to prevent highly pathogenic avian influenza H5N1 virus infection is a challenging goal. Lactococcus lactis (L. lactis) an ideal delivery vector for vaccine development, it has been shown previously that oral immunization encapsulated secretory L. lactis-hemagglutinin (HA) could provide complete protection against homologous challenge in the mice model. While intranasal appealing approach, now reported lactis-HA combined with mucosal adjuvant...

10.1002/jmv.23983 article EN Journal of Medical Virology 2014-05-26

Highly pathogenic H5N1 avian influenza viruses pose a debilitating pandemic threat in poultry. Current vaccines predominantly focus on hemagglutinin (HA) which anti-HA antibodies are often neutralizing, and used routinely to assess vaccine immunogenicity. However, Neuraminidase (NA), the other major glycoprotein surface of virus, has historically served as target for antiviral drug therapy is much less studied context humoral immunity. The aim this study was evaluate protective immunity NA...

10.1186/s12917-015-0399-4 article EN cc-by BMC Veterinary Research 2015-04-02

The freshwater mussel Hyriopsis schlegelii is a cultured bivalve in China, and the quality of pearls produced affected by type gonads. However, because lack published genome complexity sex determination, research on reversal development this species limited. In study, Illumina RNA-seq PacBio Isoform Sequencing (Iso-Seq) were combined to analyze gonads H. schlegelii. A total 201,481 high-quality transcripts generated. study identified 7,922 differentially expressed genes three comparison...

10.3389/fgene.2022.868742 article EN cc-by Frontiers in Genetics 2022-03-24

Mycoplasma ovipneumoniae, a bacterial species that specifically affects ovine and goat, is the cause of infectious pleuropneumonia.We cloned, sequenced analyzed heat shock protein 70 (HSP70) (dnaK) gene M. ovipneumoniae.The full length open reading frame ovipneumoniae HSP70 consists 1812 nucleotides, with G+C content 34.16%, encoding 604 amino acids.Comparative analysis sequences 15 revealed 59 to 87% DNA sequence identity, an acid identity range 58 94%.M. hyopneumoniae shared highest (87...

10.4238/vol10-2gmr1193 article EN Genetics and Molecular Research 2011-01-01

This study aimed to evaluate the influence of stocking density on growth performance, nutritional quality, and immune-related gene expression Eriocheir sinensis water quality in pond ecosystems. E. were randomly divided into five groups (G1: 1.2 inds/m2; G2: 1.5 G3: 1.8 G4: 2.1 G5: 2.4 inds/m2) based their breeding densities, three replicates set up for each group, a total fifteen ponds. After 169 days breeding, muscle, hepatopancreatic tissue, hemolymph sinensis, selected from collected...

10.3390/fishes7060362 article EN cc-by Fishes 2022-11-29

Summary The Betta fish displays a remarkable variety of phenotypes selected during domestication. However, the genetic basis underlying these traits remain largely unexplored. Here, we report high-quality genome assembly and re-sequencing 727 individuals representing diverse morphologies betta fish. We show that current breeds have complex domestication history with extensive introgression wild species. Using GWAS, identify multiple traits, including several coloration phenotypes,...

10.1101/2021.05.10.443352 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2021-05-10
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