A5110673725- SARS-CoV-2 and COVID-19 Research
- Nonlinear Optical Materials Studies
- Nanofabrication and Lithography Techniques
- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Multimodal Machine Learning Applications
- Quantum Dots Synthesis And Properties
- Advanced Fluorescence Microscopy Techniques
- Advanced Battery Materials and Technologies
- Organic Light-Emitting Diodes Research
- Luminescence and Fluorescent Materials
- Metal-Organic Frameworks: Synthesis and Applications
- Virus-based gene therapy research
- Flame retardant materials and properties
- Gear and Bearing Dynamics Analysis
- Domain Adaptation and Few-Shot Learning
- Advanced Battery Technologies Research
- Fire dynamics and safety research
- Lymphoma Diagnosis and Treatment
- Perovskite Materials and Applications
- Chronic Lymphocytic Leukemia Research
- Crystallization and Solubility Studies
- Advancements in Battery Materials
- ZnO doping and properties
- Natural Language Processing Techniques
Jilin University
2022-2025
State Key Laboratory of Supramolecular Structure and Materials
2022-2025
Tianjin Medical University General Hospital
2022-2025
Beijing Polytechnic
2023-2025
Lishui Central Hospital
2020-2024
Xiangtan University
2023-2024
Institute of Microbiology
2020-2024
Chinese Academy of Sciences
2020-2024
Shanghai Jiao Tong University
2024
Shandong Academy of Sciences
2022-2024
In conventional photolithography, diffraction limits the resolution to about one-quarter of wavelength light used. We introduce an approach photolithography in which multiphoton absorption pulsed 800-nanometer (nm) is used initiate cross-linking a polymer photoresist and one-photon continuous-wave 800-nm simultaneously deactivate photopolymerization. By employing spatial phase-shaping deactivation beam, we demonstrate fabrication features with scalable along beam axis, down 40-nm minimum...
Abstract Developing solution‐processable red organic light‐emitting diodes (OLEDs) with high color purity and efficiency based on multiple resonance thermally activated delayed fluorescence (MR‐TADF) is a formidable challenge. Herein, by introducing auxiliary electron donor acceptor moieties into the highest occupied molecular orbital (HOMO) lowest unoccupied (LUMO) distributed positions of skeleton simultaneously, an effective strategy to obtain MR‐TADF emitters was represented. The...
SARS-CoV-2 Omicron variant has presented significant challenges to current antibodies and vaccines. Herein, we systematically compared the efficacy of 50 human monoclonal (mAbs), covering seven identified epitope classes RBD, against sub-variants BA.1, BA.1.1, BA.2, BA.3. Binding pseudovirus-based neutralizing assays revealed that 37 mAbs lost activities, whereas others displayed variably decreased activities four sub-variants. BA.2 was found be more sensitive RBD-5 than other Furthermore, a...
The development of deep-blue organic light-emitting diodes (OLEDs) featuring high efficiency and narrowband emission is great importance for ultrahigh-definition displays with wide color gamut. Herein, based on the nitrogen-embedding strategy modifying short range charge transfer excited state energies multi-resonance (MR) thermally activated delayed fluorescence (TADF) emitters, we introduce one or two nitrogen atoms into central benzene ring a versatile boron-embedded...
The inherent optical nonlinearity of multiphoton absorption allows such to be localized in regions high light intensity. This means that photochemical or photophysical transformations can restricted occur within the focal volume a laser beam has been focused through microscope objective. By moving position, intricate three-dimensional microstructures created. most well-developed fabrication technique – polymerization enables creation large-scale structures with feature sizes as small 100 nm.
Pesticides are the primary defending strategy against major biological invaders and important for ensuring national food security. Intelligent nanopesticides with precise controlled release modes currently an emerging area of interest in field green, safe, sustainable pesticide formulation. In this study, β-cypermethrin (β-CYP) was loaded into ZIF-8 by one-pot method, which successfully prepared a pH-responsive delivery nanoparticle (β-CYP/ZIF-8) to control termites. Results demonstrated...
A semiconductor oxide composite consisting of ZnO nanorods (NRs) and inverse opal (IO) was fabricated used in the photoanode quantum dot-sensitized solar cells (QDSSCs). Using polystyrene spheres 500, 800, 1000, 1500 nm diameter as IO template, composites corresponding QDSSCs with IOs different pore sizes were fabricated. The prepared showed similar micro-morphologies; however, photovoltaic performance based on these varied greatly. achieved high power conversion efficiencies (PCEs) more...
The Omicron variant of SARS-CoV-2 carries multiple unusual mutations, particularly in the receptor-binding domain (RBD) spike (S) protein. Moreover, host-adapting such as residues 493, 498, and 501, were also observed RBD, which indicates that it is necessary to evaluate interspecies transmission risk variant. Herein, we evaluated recognition BA.1 Delta RBDs by 27 ACE2 orthologs, including humans. We found expanded its receptor binding spectra palm-civet, rodents, more bats (least horseshoe...
We propose MM-Vet, an evaluation benchmark that examines large multimodal models (LMMs) on complicated tasks. Recent LMMs have shown various intriguing abilities, such as solving math problems written the blackboard, reasoning about events and celebrities in news images, explaining visual jokes. Rapid model advancements pose challenges to development. Problems include: (1) How systematically structure evaluate tasks; (2) design metrics work well across question answer types; (3) give...
The spike protein of SARS-CoV-2 has been a promising target for developing vaccines and therapeutics due to its crucial role in the viral entry process. Previously reported cryogenic electron microscopy (cryo-EM) structures have revealed that free fatty acids (FFA) bind with protein, stabilizing closed conformation reducing interaction host cell vitro. Inspired by these, we utilized structure-based virtual screening approach against conserved FFA-binding pocket identify small molecule...
Abstract Multiple SARS-CoV-2 Omicron sub-variants, such as BA.2, BA.2.12.1, BA.4, and BA.5, emerge one after another. BA.5 has become the dominant strain worldwide. Additionally, BA.2.75 is significantly increasing in some countries. Exploring their receptor binding interspecies transmission risk urgently needed. Herein, we examine capacities of human other 28 animal ACE2 orthologs covering nine orders towards S proteins these sub-variants. The affinities between hACE2 sub-variants remain...
Abstract Although CD19-specific chimeric antigen receptor (CAR) T cells are curative for patients with relapsed or refractory large B-cell lymphoma (R/R LBCL), disease relapse tumor antigen-positive remains a challenge. Cytokine/chemokine-expressing CAR-T could overcome suppressive milieu, but the clinical safety and efficacy of this therapy remain unclear. Here we report preclinical development capable expressing interleukin (IL)-7 chemokine (C-C motif) ligand (CCL)-19 upon CD19 engagement...
Abstract Aqueous zinc‐ion batteries (AZIBs) directly using zinc metal anodes are promising candidates for grid‐scale energy storage systems due to their intrinsic high theoretical capacity, safety, and environmental friendliness. However, the uncontrolled dendrite growth water‐triggered side reactions seriously plague its practical application. Herein, a cost‐effective green additive, maltodextrin (MD) is presented, simultaneously guide smooth Zn deposition inhibit occurrence of...
Crystal gazing: A mild solution route has been designed for the controlled synthesis of lead tungstate microcrystals with high crystal symmetry, in which cationic surfactant, pH value, and temperature play key roles. Helix- (see TEM image), spindle-, chainlike, dendritic structures can be produced by varying reaction conditions.
We demonstrate the selective functionalization of 3-D polymer microstructures that were created using multiphoton absorption polymerization. By fabricating different portions structures with acrylic and methacrylic polymers, we are able to take advantage differential reactivities these materials perform chemistry on a single polymeric component. deposition metal create structures, such as functional microinductor. Our strategy is quite general can be extended readily materials, oxides biomolecules.