A5101684306- Insect symbiosis and bacterial influences
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Protein Hydrolysis and Bioactive Peptides
- Consumer Attitudes and Food Labeling
- Diet, Metabolism, and Disease
- Mosquito-borne diseases and control
- Insect Utilization and Effects
- Natural product bioactivities and synthesis
- Mycorrhizal Fungi and Plant Interactions
- Cardiac Arrhythmias and Treatments
- Microbial Natural Products and Biosynthesis
- Bacteriophages and microbial interactions
- Alcohol Consumption and Health Effects
- Hearing, Cochlea, Tinnitus, Genetics
- Cholesterol and Lipid Metabolism
- Malaria Research and Control
- Molecular Biology Techniques and Applications
- Cancer, Lipids, and Metabolism
- Aquaculture Nutrition and Growth
- Congenital heart defects research
- Cardiomyopathy and Myosin Studies
- Liver Disease Diagnosis and Treatment
- Inflammatory Biomarkers in Disease Prognosis
- Evolution and Genetic Dynamics
Xuzhou Medical College
2023
National Institute for Communicable Disease Control and Prevention
2023
Shanghai Jiao Tong University
2013-2021
Chongqing University of Education
2019
Yale University
2014-2018
Soochow University
2015
University of Tübingen
2010
Dalian University of Technology
2010
Fructose as a daily sweetener is widely recognized risk catalyst for nonalcoholic fatty liver disease (NAFLD). The aim of current study to evaluate the effects and molecular mechanism by which polyphenol-rich loquat fruit extract (LFP) prevents NAFLD in mice fed 30% fructose water (HF) 8 weeks. Administration LFP HF-fed mitigated abnormal body weight, disordered lipid metabolism, oxidative stress, inflammation through regulated AKT, ChREBP/SREBP-1c, Nrf2, TLR4/MyD88/TRIF pathways. caused...
Tsetse flies (Glossina sp.) are the vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. distinguished from other Diptera by unique adaptations, including lactation birthing live young (obligate viviparity), a vertebrate blood-specific diet both sexes, obligate bacterial symbiosis. This work describes comparative analysis six Glossina genomes representing three sub-genera: Morsitans (G. morsitans morsitans, G. pallidipes, austeni), Palpalis palpalis, fuscipes), Fusca...
The agents of sleeping sickness disease, Trypanosoma brucei complex parasites, are transmitted to mammalian hosts through the bite an infected tsetse. Information on tsetse-trypanosome interactions in salivary gland (SG) tissue, and infective metacyclic (MC) parasites present SG, is sparse. We performed RNA-seq analyses from uninfected T. b. SGs Glossina morsitans morsitans. Comparison SG transcriptomes a whole body fly transcriptome revealed that only 2.7% contigs differentially expressed...
Abstract Recent studies have confirmed that the peptide fractions derived from marine organisms exhibit good antioxidant and anti‐inflammatory activity, oyster is an excellent nutrient resource with high‐protein content. In this study, soft tissue were prepared after hydrolysis by pepsin (pH 2, 37°C), trypsin 8, Maxipro PSP 4.2, 50°C) optimized parameters (enzyme‐to‐substrate (E/S) ratio, 1:100 (w/w); time, 4 hr), respectively. Four named as PEP‐1, PEP‐2, TRYP‐2, MIX‐2 obtained separation...
BACKGROUND Studies have revealed that having systemic inflammation is linked to worse survival rates across a range of malignancies. This study aimed evaluate the predictive significance neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), and lymphocyte-to-monocyte (LMR) in combination with fibrinogen-to-albumin (FAR) surgical patients colorectal adenocarcinoma (CRC). MATERIAL AND METHODS From January 2010 December 2016, 200 CRC had their preoperative NLR, PLR, LMR, FAR...
Arthropod vectors have multiple physical and immunological barriers that impede the development transmission of parasites to new vertebrate hosts. These include peritrophic matrix (PM), a chitinous barrier separates blood bolus from midgut epithelia modulates vector-pathogens interactions. In tsetse flies, sleeve-like PM is continuously produced by cardia organ located at fore- junction. African trypanosomes, Trypanosoma brucei, must bypass twice; first colonize secondly reach salivary...
In this study, two hexapeptides of IPPVPP and VPPIPP were innovated by using commercial antihypertensive peptides IPP VPP as domains cis-linked trans-linked, respectively. The chemically synthesized evaluated for the activity in vitro/vivo. vitro ACE-inhibitory study showed that (34.71±4.38%) has a significantly stronger than (13.17±0.25%) at treatment concentration 10 µmol/L, but it was weaker (56.97±2.40%) (P<0.05). However, VPPIPP, IPPVPP, lowered systolic blood pressure 21±0.9%,...
A safe polymer limits the absorption of a broad spectrum saccharides in gut to manage metabolic disorders.
Tsetse are vectors of pathogenic trypanosomes, agents human and animal trypanosomiasis in Africa. Components tsetse saliva (sialome) introduced into the mammalian host bite site during blood feeding process important for tsetse’s ability to feed efficiently, but can also influence disease transmission serve as biomarkers exposure. We compared sialome components from four species two subgenera: subgenus Morsitans: Glossina morsitans (Gmm) pallidipes (Gpd), Palpalis: palpalis gambiensis (Gpg)...
The current prevention and control strategy for Aedes albopictus heavily relies on comprehensive management, such as environmental management chemical control. However, the wide application of pyrethroids has facilitated development insecticide resistance, primarily via mutations in voltage-gated sodium channel (VGSC) gene. This study aims to develop a novel detecting VGSC gene Ae. using multiplex PCR-mass spectrometry (MPCR-MS) minisequencing technology.We established new MPCR-MS...
Background: Tsetse flies (Glossina sp.) are the sole vectors of human and animal trypanosomiasis throughout sub-Saharan Africa. distinguished from other Diptera by unique adaptations, including lactation birthing live young (obligate viviparity), a vertebrate blood specific diet both sexes obligate bacterial symbiosis. This work describes comparative analysis six Glossina genomes representing three sub-genera: Morsitans (G. morsitans (G.m. morsitans), G. pallidipes, austeni), Palpalis...
Abstract To develop the potential applications of Plantago plants, seed oils were extracted from 14 cultivars around China. Their fatty acid profiles, tocopherols, carotenoid compositions, anti‐inflammatory and antioxidant properties also investigated. The (PSO) abundant in linolenic 11.12 to 29.36 g/100 g oil had low ratio n‐6/n‐3 matched with dietary recommendations. tocopherol contents PSO ranged 693.25 3708.80 μg/g lutein 2.29 26.68 μg/g. showed significant inhibitory effects on TNF‐α,...
Abstract Arthropod vectors have multiple physical and immunological barriers that impede the development transmission of parasites to new vertebrate hosts. These include peritrophic matrix (PM), a chitinous barrier separates blood bolus from midgut epithelia inturn, modulates vector-microbiota interactions. In tsetse flies, sleeve-like PM is continuously produced by cardia organ located at fore- junction. African trypanosomes, Trypanosoma brucei , must bypass twice; first colonize secondly...
Multiplex PCR-SSCP: A highly effective and efficient method of mutation detection analysis