A5013246214- Aquaculture Nutrition and Growth
- Aquaculture disease management and microbiota
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Physiological and biochemical adaptations
- Invertebrate Immune Response Mechanisms
- Reproductive biology and impacts on aquatic species
- Neurobiology and Insect Physiology Research
- Crustacean biology and ecology
- Fish Ecology and Management Studies
- Drug Transport and Resistance Mechanisms
- Genetic diversity and population structure
- Animal Nutrition and Physiology
- Genomics and Chromatin Dynamics
- Fish Biology and Ecology Studies
- Lipid metabolism and biosynthesis
- Cell Image Analysis Techniques
- Pancreatitis Pathology and Treatment
- Plant Molecular Biology Research
- Esophageal Cancer Research and Treatment
- Gene Regulatory Network Analysis
- Single-cell and spatial transcriptomics
- Esophageal and GI Pathology
- Gastric Cancer Management and Outcomes
- Hypothalamic control of reproductive hormones
- Moringa oleifera research and applications
Soochow University
2012-2024
Hunan Normal University
2021-2024
Taipei Medical University Hospital
2023
Princeton University
2021-2022
Xuzhou Central Hospital
2012-2019
East China Normal University
2008-2016
National Taiwan University Hospital
2012
Taipei City Hospital
2012
Far Eastern Memorial Hospital
2012
Taipei Municipal YangMing Hospital
2012
Developmental patterning networks are regulated by multiple inputs and feedback connections that rapidly reshape gene expression, limiting the information can be gained solely from slow genetic perturbations. Here we show fast optogenetic stimuli, real-time transcriptional reporters, a simplified background combined to reveal kinetics of expression downstream developmental transcription factor in vivo. We engineer light-controlled versions Bicoid study their effects on gap genes embryos. Our...
Despite the efficacy of antihypertensive treatment in preventing cardiovascular complications, there are often problems with medication adherence hypertensive patients. The objective this study was to examine and its association blood pressure (BP) control, disease (CVD) hospitalization, all-cause hospitalization.We conducted a retrospective cohort observation patients who were treated for hypertension from January 2005 December 2006. Medical pharmacy claims obtained Taiwan's National Health...
ABSTRACT Optical pooled screening (OPS) is a highly scalable method for linking image-based phenotypes with cellular perturbations. However, it has thus far been restricted to relatively low-plex phenotypic readouts in cancer cell lines culture, due limitations associated situ sequencing (ISS) of perturbation barcodes. Here, we developed PerturbView, an OPS technology that leverages vitro transcription (IVT) amplify barcodes prior ISS, enabling screens multiplexed across diverse systems,...
This study reports a new white-rot fungus Cerrena sp. WR1, identified based on an 18S rDNA sequence, which can secrete extracellular forms of laccase with maximal activity reaching 202 000 U l−1 in 5-l fermenter. A protein, designated Lcc3, was purified and shown to be N-linked glycosylated by PNGase F liquid chromatography tandem mass spectrometry analyses. The respective full-length cDNA gene (lcc3) the Lcc3 protein obtained using polymerase chain reaction-based methods. Kinetic studies...
The gustavus gene is required for localizing pole plasm and specifying germ cells. Research on expression will advance our understanding of the biological function in animals. A cDNA encoding protein was identified termed MnGus oriental river prawn Macrobrachium nipponense. Bioinformatic analyses showed that this encoded a 262 amino acids belongs to Spsb1 family. Real-time quantitative PCR revealed level embryos slightly higher at cleavage stage than blastula stage, reached maximum during...
The concentration of butyric acid in the intestine increased with increase content fermentable dietary fibre; however, potential physiological impact a high dose on fish has not been sufficiently studied. aim this study was to investigate effect two dosages growth and health liver largemouth bass (Micropterus salmoides). Sodium butyrate (SB) added diet at 0 g/kg (CON), 2 (SB2), 20 (SB20), juvenile were fed apparent satiation for 56 days. No significant difference observed specific rate or...
We identified the cDNA sequence of cathepsin L (CatL) in Macrobrachium nipponense, designated as MnCatL, for first time. The MnCatL cDNA, isolated from ovary, was 1710 bp length, containing a 31-bp 5'-untranslated region, 650-bp 3'-untranslated and an open reading frame 1029 bp, encoding 342-amino acid polypeptide with predicted molecular mass 37.7 kDa. is composed 18-amino signal peptide, 106-amino propeptide 218-amino mature peptide. mRNA detected all tissues that we examined, including...