A5109980027- Chromosomal and Genetic Variations
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Reproductive biology and impacts on aquatic species
- Animal Genetics and Reproduction
- Aquaculture disease management and microbiota
- Aquaculture Nutrition and Growth
- Genetic diversity and population structure
- CRISPR and Genetic Engineering
- Fish Ecology and Management Studies
- Fish Biology and Ecology Studies
- Evolution and Genetic Dynamics
- MicroRNA in disease regulation
- Genomics and Phylogenetic Studies
- Physiological and biochemical adaptations
- Cancer-related molecular mechanisms research
- Fish biology, ecology, and behavior
- RNA modifications and cancer
- Genetic Mapping and Diversity in Plants and Animals
- Sperm and Testicular Function
- Mitochondrial Function and Pathology
- interferon and immune responses
- Invertebrate Immune Response Mechanisms
- Cancer, Hypoxia, and Metabolism
- Hypothalamic control of reproductive hormones
- Growth Hormone and Insulin-like Growth Factors
Hunan Normal University
2016-2025
Key Laboratory of Guangdong Province
2022-2024
Suzhou Traditional Chinese Medicine Hospital
2023-2024
Nanjing University
2024
Central South University
2015-2024
South China Agricultural University
2022-2024
Third Xiangya Hospital
2015-2024
Huashan Hospital
2024
Fudan University
2024
University of Science and Technology of China
2021-2023
Fisheries is a social production sector that captures and farms fish other aquatic animals plants for products. In broad sense, fisheries also include upstream departments (e.g., manufacturing, maintenance supply of fishing gear, boats, fishery machinery, instruments means production), downstream storage, processing, comprehensive utilization, transportation sales products), auxiliary the construction ports). As an important constituent part national economy in China, not only provide large...
Background Digestive diseases are very common worldwide and account for considerable health care use expenditures. However, there no global population-based estimates of the disease burden temporal trend digestive diseases. Methods Annual case numbers, age-standardized rates prevalence, incidence, death, disability-adjusted life-years (DALYs), their estimated annual percentage changes (EAPCs) between 1990 2019 were derived from Global Burden Disease, Injuries, Risk Factors Study (GBD) 2019....
Significance Why is polyploidization rarer in animals than plants? This question remains unanswered due to the absence of a suitable system for studying instantaneous and crucial changes that immediately follow hybridization. RNA-seq analyses discover extensive chimeric genes immediate mutations orthologs both diploid tetraploid offspring goldfish (♀) × common carp (♂) hybrids. Overall, show paternal-biased expression, yet tetraploids maternal-biased expression. Some differentially expressed...
A persistent enigma is the rarity of polyploidy in animals, compared to its prevalence plants. Although animal polyploids are thought experience deleterious genomic chaos during initial polyploidization and subsequent rediploidization processes, this hypothesis has not been tested. We provide an improved reference-quality de novo genome for allotetraploid goldfish whose origin dates ~15 million years ago. Comprehensive analyses identify changes subgenomic evolution from asymmetrical...
Largemouth bass (Micropterus salmoides, LB) is an important aquaculture and fishing species in the world. LB has been introduced into China since 1983, its production increased year by year. The total yield of reached 802,486 tons 2022, ranking seventh China's freshwater fish aquaculture. However, facing threats such as degradation germplasm resources disease susceptibility due to limitations scale introduction, coupled with effects high-density aquaculture, inbreeding, hybridization. This...
This study provides genetic evidences at the chromosome, DNA content, fragment and sequence, morphological levels to support successful establishment of polyploid hybrids red crucian carp x blunt snout bream, which belonged a different subfamily fish (Cyprininae Cultrinae subfamily) in catalog. We successfully obtained sterile triploid bisexual fertile tetraploid (RCC) (female symbol) bream (BSB) (male as well their pentaploid hybrids. The possessed 124 chromosomes with two sets from RCC one...
Abstract Background Crucian carp (abbreviated CC) belongs to the genus of Carassius within family Cyprinidae . It has been one most important freshwater species for Chinese aquaculture and is especially abundant in Dongting water system Hunan province. CC used be considered as all diploid forms. However, coexistence 2nCC), triploid 3nCC) tetraploid crucian 4nCC) population was first found by our recently researches. Results We examined ploidy level compared biological characteristics...
miR-124 and miR-506 are reportedly down-regulated associated with tumor progression in many cancers, but little is known about their intrinsic regulatory mechanisms colorectal cancer (CRC). In this study, we found that the levels were significantly lower human CRC tissues than controls, as indicated by qRT-PCR situ hybridization histochemistry. We also overexpression of or inhibited cell increased sensitivity to chemotherapy vitro. Increased expression proliferation invasion vivo. Luciferase...
The establishment of the tetraploid organism is difficult but useful in genetics and breeding. In present study, we have artificially established an autotetraploid fish line (F2–F8) derived from distant hybridization Carassius auratus red var. (RR, 2n = 100) (female) × Megalobrama amblycephala (BB, 48) (male). possess four sets chromosomes crucian carp (RRRR, 4n 200) produce diploid ova sperm, which maintains formation line. F2 result fertilization autodiploidy eggs sperm females males F1...
Hybridization drives rapid speciation by shaping novel genotypic and phenotypic profiles. Genomic incompatibility transcriptome shock have been observed in hybrids, although this is rarer animals than plants. Using the newly sequenced genomes of blunt snout bream ( Megalobrama amblycephala [BSB]) topmouth culter Culter alburnus [TC]), we focused on sequence variation gene expression changes reciprocal intergeneric hybrid lineages (F 1 –F 3 ) BSB × TC. A genome-wide transcriptional analysis...
Gut microbiota play critical roles in host nutrition and metabolism. However, little is known about the genetic effects on gut assemblages because a suitable model for investigation lacking. In present study, we established reciprocal hybrid fish lineages derived from parents with different feeding habits, namely, herbivorous blunt snout bream (Megalobrama amblycephala, BSB, 2n = 48) carnivorous topmouth culter (Culter alburnus, TC, 48). We investigated by using 16S rRNA gene sequencing. The...
In this research, we studied the antioxidative properties and chemical changes of quercetin in fish oil during accelerated storage at 60 °C for 5 days. Gas chromatography (GC) analysis showed that inhibited aldehyde formation unsaturated fatty acid oxidation significantly; however, inhibitory effects decreased gradually with prolonged heating time. Moreover, was consumed increasing Some new phenolic derivatives were discovered quercetin, their structures fully elucidated by LC–MS/MS...