Jian Xu

ORCID: 0000-0003-0274-4268
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About
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Research Areas
  • Genomics and Phylogenetic Studies
  • Aquaculture disease management and microbiota
  • Aquaculture Nutrition and Growth
  • Genetic and phenotypic traits in livestock
  • Fish Ecology and Management Studies
  • Fish Biology and Ecology Studies
  • Physiological and biochemical adaptations
  • Genetic diversity and population structure
  • Identification and Quantification in Food
  • Enzyme Catalysis and Immobilization
  • Animal Genetics and Reproduction
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • melanin and skin pigmentation
  • Ichthyology and Marine Biology
  • Insect Resistance and Genetics
  • Catalysis for Biomass Conversion
  • Microbial Metabolic Engineering and Bioproduction
  • CRISPR and Genetic Engineering
  • Genetic Mapping and Diversity in Plants and Animals
  • Influenza Virus Research Studies
  • Animal Disease Management and Epidemiology
  • Viral Infections and Vectors
  • Viral Infectious Diseases and Gene Expression in Insects
  • Invertebrate Immune Response Mechanisms

Fudan University
2025

Zhongshan Hospital
2025

Chinese Academy of Fishery Sciences
2014-2024

Shaoguan University
2024

Nanjing University of Information Science and Technology
2024

China Tobacco
2018-2024

Jilin Agricultural University
2023

Northeast Forestry University
2022-2023

Ministry of Agriculture and Rural Affairs
2021-2022

Wenzhou Vocational College of Science and Technology
2019-2022

Xiaowen Sun and colleagues report the whole-genome sequencing of common carp, Cyprinus carpio. They also resequenced 33 representative accessions from a worldwide collection provide insights into population structure evolution. The carpio, is one most important cyprinid species globally accounts for 10% freshwater aquaculture production. Here we present draft genome domesticated C. carpio (strain Songpu), whose current assembly contains 52,610 protein-coding genes approximately 92.3%...

10.1038/ng.3098 article EN cc-by-nc-sa Nature Genetics 2014-09-21

Abstract Common carp ( Cyprinus carpio ) is an allotetraploid species derived from recent whole genome duplication and provides a model to study polyploid evolution in vertebrates. Here, we generate three chromosome-level reference genomes of C. compare related diploid Cyprinid genomes. We identify Barbinae lineage as potential progenitor then divide the into two subgenomes marked by distinct similarity progenitor. estimate that progenitors diverged around 23 Mya merged 12.4 based on...

10.1038/s41467-019-12644-1 article EN cc-by Nature Communications 2019-10-11

Background Common carp (Cyprinus carpio) is one of the most important aquaculture species Cyprinidae with an annual global production 3.4 million tons, accounting for nearly 14% freshwater in world. Due to economical and ecological importance common carp, genomic data are eagerly needed genetic improvement purpose. However, there still no sufficient transcriptome available. The objective project sequence deeply provide well-assembled sequences research community. Result Transcriptome...

10.1371/journal.pone.0035152 article EN cc-by PLoS ONE 2012-04-13

A large number of single nucleotide polymorphisms (SNPs) have been identified in common carp (Cyprinus carpio) but, as yet, no high-throughput genotyping platform is available for this species. C. carpio an important aquaculture species that accounts nearly 14% freshwater production worldwide. We developed array with 250,000 SNPs and evaluated its performance using samples from various strains carpio. The used on the were selected two resources: transcribed sequences RNA-seq data four...

10.1186/1471-2164-15-307 article EN cc-by BMC Genomics 2014-01-01

High density genetic linkage maps are essential for QTL fine mapping, comparative genomics and high quality genome sequence assembly. In this study, we constructed a high-density high-resolution map with 28,194 SNP markers on 14,146 distinct loci common carp based high-throughput genotyping the 250 K single nucleotide polymorphism (SNP) array in mapping family. The length of consensus was 10,595.94 cM an average locus interval 0.75 marker 0.38 cM. Comparative genomic analysis revealed level...

10.1038/srep26693 article EN cc-by Scientific Reports 2016-05-26

Background The common carp is an important aquaculture species that widely distributed across the world. During long history of domestication, numerous strains with diverse skin colors have been established. Skin color used as a visual criterion to determine market value carp. However, genetic basis has not extensively studied. Methodology/Principal Findings In this study, we performed Illumina sequencing on two strains: reddish Xingguo red and brownish-black Yellow River A total 435,348,868...

10.1371/journal.pone.0108200 article EN cc-by PLoS ONE 2014-09-25

A persistent enigma is the rarity of polyploidy in animals, compared to its prevalence plants. Although animal polyploids are thought experience deleterious genomic chaos during initial polyploidization and subsequent rediploidization processes, this hypothesis has not been tested. We provide an improved reference-quality de novo genome for allotetraploid goldfish whose origin dates ~15 million years ago. Comprehensive analyses identify changes subgenomic evolution from asymmetrical...

10.1126/sciadv.aaz7677 article EN cc-by-nc Science Advances 2020-05-27

The Amur ide (Leuciscus waleckii) is a cyprinid fish that widely distributed in Northeast Asia. Lake Dali Nur population inhabits one of the most extreme aquatic environments on Earth, with an alkalinity up to 50 mmol/L (pH 9.6), thus providing exceptional model which characterize mechanisms genomic evolution underlying adaptation environments. Here, we developed reference genome assembly for L. waleckii from Nur. Intriguingly, identified unusual expanded long terminal repeats (LTRs) higher...

10.1093/molbev/msw230 article EN cc-by-nc Molecular Biology and Evolution 2016-10-15

Background Single nucleotide polymorphisms (SNPs) have been used as genetic marker for genome-wide association studies in many species. Gene-associated SNPs could offer sufficient coverage trait related research and further more themselves be causative traits. Common carp (Cyprinus carpio) is one of the most important aquaculture species world accounting nearly 14% freshwater production. There are various strains common with different economic traits, however, mechanism underlying traits not...

10.1371/journal.pone.0048140 article EN cc-by PLoS ONE 2012-10-26

Abstract Background The Northern snakehead (Channa argus), a member of the Channidae family Perciformes, is an economically important freshwater fish native to East Asia. In North America, it has become notorious as intentionally released invasive species. Its ability breathe air with gills and migrate short distances over land makes good model for bimodal breath research. Therefore, recent research focused on identification relevant candidate genes. Here, we performed whole genome...

10.1093/gigascience/gix011 article EN cc-by GigaScience 2017-03-02

Background Amur ide (Leuciscus waleckii) is an economically and ecologically important species in Northern Asia. The Dali Nor population inhabiting Lake, a typical saline-alkaline lake Inner Mongolia, well-known for its adaptation to extremely high alkalinity. Genome information needed conservation aquaculture purposes, as well gain further understanding into the genetics of stress tolerance. objective study sequence transcriptome obtain well-assembled ide. Results was sequenced using...

10.1371/journal.pone.0059703 article EN cc-by PLoS ONE 2013-04-01

Abstract Aquatic species have become an integral part of human culture. As internationally important food fish species, the common carp Cyprinus carpio accounted for over 7% global aquaculture production in 2020. In addition to serving as a source, varieties are used ornamental and valued recreational fisheries. The continuously updated reference genome has recently served foundation both basic genetic studies evolutionary studies. With recent emphasis on allotetraploid signature carp,...

10.1111/raq.12636 article EN Reviews in Aquaculture 2021-11-26

Amur ide (Leuciscus waleckii) is an economically and ecologically important cyprinid species in Northern Asia. The Dali Nor population living the soda lake can adapt extremely high alkalinity, providing us a valuable material to understand adaptation mechanism against extreme environmental stress teleost. In this study, we generated high-throughput RNA-Seq data from three tissues gill, liver kidney of L. waleckii fresh water Ganggeng Nor, then performed parallel comparisons tissues. Our...

10.1186/1471-2164-14-682 article EN cc-by BMC Genomics 2013-01-01

Docosahexaenoic acid (DHA) is an essential nutrient for humans and plays a critical role in human development health. Freshwater fish, such as the common carp (Cyprinus carpio), have certain degree of DHA biosynthesis ability could be supplemental source needs. The elongase very-long-chain fatty 5 (Elovl5) important enzyme affecting polyunsaturated (PUFA) biosynthesis. However, function regulatory mechanism elovl5 gene related to synthesis freshwater fish not clear yet. Previous studies...

10.3390/ani14040544 article EN cc-by Animals 2024-02-06

Background Aquaporins (Aqps) are integral membrane proteins that facilitate the transport of water and small solutes across cell membranes. Among vertebrate species, Aqps highly conserved in both gene structure amino acid sequence. These vital for maintaining homeostasis living organisms, especially aquatic animals such as teleost fish. Studies on mainly limited to several model species with diploid genomes. Common carp, which has a tetraploidized genome, is one most common aquaculture being...

10.1371/journal.pone.0166160 article EN cc-by PLoS ONE 2016-12-09

Abstract The mechanism of osmoregulation is crucial for maintaining growth, development, and life activities in teleosts. Takifugu obscurus, the only euryhaline species genus Takifugu, a proper model organism studying low-salt tolerance hypoosmotic regulation. In this study, whole-genome sequencing data were obtained from 90 pufferfish representing five within genus, T. rubripes, flavidus, niphobles, bimaculatus. Using phylogeny, PCA, population structure analyses, we observed similar...

10.1007/s00227-020-03705-x article EN cc-by Marine Biology 2020-06-03

Polyunsaturated fatty acids (PUFAs) are a set of important nutrients that mainly include arachidonic acid (ARA4), docosahexenoic (DHA), eicosapentaenoic (EPA), and α-linolenic (ALA). Recently, fish-derived PUFAs have been associated with cardiovascular health, fetal development, improvement brain functions. Studies shown fish muscular tissues rich in PUFAs, which influenced by various factors, including genetic variations, regulatory profiles, methylation status desaturase genes during...

10.3389/fgene.2019.00217 article EN cc-by Frontiers in Genetics 2019-03-15

Ogura-type cytoplasmic male sterility (Ogura-CMS) has been widely used in the hybrid breeding industry for cruciferous vegetables. Turnip (Brassica rapa ssp. rapifera) is one of most important local vegetables China, cultivated its fleshy root as a flat disc. Here, morphological characteristics an Ogura-CMS line 'BY10-2A' and maintainer fertile (MF) 'BY10-2B' turnip were investigated. showed reduction size root, had distinct defects microspore development tapetum degeneration during...

10.1371/journal.pone.0218029 article EN cc-by PLoS ONE 2019-06-14

A process for preparing chiral secondary alcohols by chemoenzymatic deracemization was optimized. First, the transesterification of 1-indanol and 1-phenylethanol with vinyl acetate as acyl donor optimized using lipase Novozym 435 biocatalyst. The effects donors, substrate concentration, solvent type, enzyme amount on activity enantioselectivity said were investigated. Second,on basis conditions, an efficient biocatalytic resolution system established high selectivity, where volumetric...

10.1021/op700253t article EN Organic Process Research & Development 2008-02-07
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