A5051391732- Aquaculture disease management and microbiota
- Animal Virus Infections Studies
- Monoclonal and Polyclonal Antibodies Research
- Geology and Paleoclimatology Research
- Periodontal Regeneration and Treatments
- Aquaculture Nutrition and Growth
- Bone and Dental Protein Studies
- Invertebrate Immune Response Mechanisms
- Virology and Viral Diseases
- Bacteriophages and microbial interactions
- Geochemistry and Elemental Analysis
- Geological formations and processes
- Isotope Analysis in Ecology
- Advanced Biosensing Techniques and Applications
- Viral Infectious Diseases and Gene Expression in Insects
- Toxoplasma gondii Research Studies
- dental development and anomalies
- Paleontology and Stratigraphy of Fossils
- Corrosion Behavior and Inhibition
- Hydrocarbon exploration and reservoir analysis
- Autophagy in Disease and Therapy
- Immunotherapy and Immune Responses
- Metal and Thin Film Mechanics
- Virus-based gene therapy research
- interferon and immune responses
Chinese Academy of Fishery Sciences
2016-2025
China Agricultural University
2022-2025
China Geological Survey
2023
Zhejiang University of Science and Technology
2023
Mudanjiang Medical University
2022-2023
Anhui Agricultural University
2023
Communication University of China
2023
First Affiliated Hospital Zhejiang University
2022
China National Petroleum Corporation (China)
2016-2021
Ministry of Agriculture and Rural Affairs
2020-2021
Xiaowen Sun and colleagues report the whole-genome sequencing of common carp, Cyprinus carpio. They also resequenced 33 representative accessions from a worldwide collection provide insights into population structure evolution. The carpio, is one most important cyprinid species globally accounts for 10% freshwater aquaculture production. Here we present draft genome domesticated C. carpio (strain Songpu), whose current assembly contains 52,610 protein-coding genes approximately 92.3%...
Identification of the gut microbiome compositions associated with disease has become a research focus worldwide. Emerging evidence revealed presence microbiota dysbiosis in Parkinson's disease. In this study, we aimed to identify and subsequently screen validate potential diagnostic biomarkers This case-control study investigated microbial genes faeces from 40 volunteer Chinese patients their healthy spouses using shotgun metagenomic sequencing. Furthermore, identified specific gene markers...
The rib fracture is a common type of thoracic skeletal trauma, and its inspections using computed tomography (CT) scans are critical for clinical evaluation treatment planning. However, it often challenging radiologists to quickly accurately detect fractures due tiny objects blurriness in large 3D CT images. Previous diagnoses automatic mostly relied on deep learning (DL)-based object detection, which highly depends label quality quantity. Moreover, general detection methods did not take...
This study addresses the challenges of high resistance, energy consumption, and complex operations in deep trenching orchards by proposing a reverse backfilling scheme. A reverse-rotating chain trencher was designed for integrated backfilling. Through mechanical analysis MBD-DEM coupled simulation, operating parameters affecting process were identified. three-factor, three-level test with forward speed(v), rotation speed(n), working angle(γ) determined optimal as v=0.29 km/h, n=393r/min,...
This study developed a chain counter-rotating trenching and backfilling device to reduce high tillage resistance in orchard operations. A 3D mathematical model of the blade was created using Cartesian coordinate transformation. Taking curvature (β), curve angle (α), bend radius (R), cone residual (θ) as experimental factors, soil cutting evaluation index. The optimized parameters were β=95°, α=10°, R=24 mm, θ=39°. Bench tests performed with optimal parameters, results showed that ditching...
The journal retracts the article “Andrographolide Alleviates Oxidative Damage and Inhibits Apoptosis Induced by IHNV Infection via CTSK/BCL2/Cytc Axis” [...]
Infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic (IPNV) are important pathogens of salmon trout. An active bivalent DNA vaccine was constructed with the glycoprotein gene Chinese IHNV isolate Sn1203 VP2-VP3 IPNV ChRtm213. Rainbow trout (5 g) were vaccinated by intramuscular injection 1.0 µg then challenged an intraperitoneal IHNV, IPNV, or both, at 30 60 days post-vaccination (d.p.v.). High protection rates against observed, 6% 10% cumulative mortality, respectively,...
Both infectious hematopoietic necrosis virus (IHNV) and pancreatic (IPNV) are the causative agents of acute highly contagious diseases juvenile salmonids, resulting in severe economic losses to these cold-water fish globally. There is an urgent need explore antiviral against IHNV IPNV due lack commercially available vaccines drugs. More importantly, co-infection prevalent nature, which not only aggravates extensive damage salmonids but also poses challenges its prevention control. The...
ABSTRACT Infectious hematopoietic necrosis virus (IHNV) causes infectious and severe economic losses to salmon trout aquaculture worldwide. Currently, the only commercial vaccine against IHNV is a DNA with some biosafety concerns. Hence, more effective vaccines antiviral drugs are needed prevent infection. In this study, 1,483 compounds were screened from traditional Chinese medicine monomer library, bufalin showed potential activity IHNV. The 50% cytotoxic concentration of was >20 µM,...
Infectious hematopoietic necrosis virus (IHNV) is the most important pathogen threatening aquaculture of salmonid fish in China. In this study, a DNA vaccine, designated pIHNch-G, was constructed with glycoprotein (G) gene Chinese IHNV isolate SD-12 (also called Sn1203) genotype J. The minimal dose vaccine required, expression Mx-1 muscle (vaccine delivery site) and anterior kidney, titers neutralizing antibodies produced were used to evaluate efficacy. To assess potential utility...