A5078875524- Nanoplatforms for cancer theranostics
- Liver Disease Diagnosis and Treatment
- Advanced MEMS and NEMS Technologies
- Mechanical and Optical Resonators
- Photoacoustic and Ultrasonic Imaging
- Lubricants and Their Additives
- Spine and Intervertebral Disc Pathology
- Bayesian Modeling and Causal Inference
- Advanced Nanomaterials in Catalysis
- Advancements in PLL and VCO Technologies
- Bone Tissue Engineering Materials
- Hepatitis B Virus Studies
- Particle Detector Development and Performance
- Photonic and Optical Devices
- Asphalt Pavement Performance Evaluation
- Infrastructure Maintenance and Monitoring
- Pharmacological Effects of Natural Compounds
- Pickering emulsions and particle stabilization
- Nanoparticle-Based Drug Delivery
- Tribology and Wear Analysis
- Geophysics and Sensor Technology
- Cancer-related molecular mechanisms research
- Hepatitis C virus research
- Enhanced Oil Recovery Techniques
- Pain Mechanisms and Treatments
Xi’an Jiaotong-Liverpool University
2025
China Agricultural University
2024-2025
North China University of Science and Technology
2025
Civil Aviation Flight University of China
2024
Weifang Medical University
2023-2024
University of Chinese Academy of Sciences
2018-2024
Chinese Academy of Sciences
2018-2024
Shanghai Advanced Research Institute
2024
Guangzhou University
2024
Ministry of Agriculture and Rural Affairs
2024
Metastasis is one of the main causes failure in treatment triple-negative breast cancer (TNBC). Immunotherapy brings hope and opportunity to solve this challenge, while its clinical applications are greatly inhibited by tumor immunosuppressive environment. Here, an intelligent biomimetic nanoplatform was designed based on dendritic large-pore mesoporous silica nanoparticles (DLMSNs) for suppressing metastatic TNBC combining photothermal ablation immune remodeling. Taking advantage ordered...
Triple-negative breast cancer (TNBC) is an aggressive subset of and currently lacks effective therapeutic targets. As two main phototherapeutic methods, photothermal therapy (PTT) photodynamic (PDT) show many advantages in TNBC treatment, their combination with chemotherapy can achieve synergistic effects. In the present study, a biomimetic nanoplatform was developed based on leukocyte/platelet hybrid membrane (LPHM) dendritic large pore mesoporous silicon nanoparticles (DLMSNs). A near...
Dendritic large-pore mesoporous silica nanoparticles (DLMSN) is an important biodegradable drug carrier due to its high porosity, which can be prepared by coassembly of a major template and auxiliary in aqueous solution, followed hydrolysis tetraethyl orthosilicate (TEOS). The key obtaining dendritic structures; however, how choose the obtain desired pore structure largely unknown. This because formation mechanism DLMSN still not clear. In this study, series therapeutic agent molecules were...
With the development of implant applications, osseointegration has become a criterion for success. A good blood supply is essential successful osseointegration. To improve pro-angiogenic ability implants, in this experiment we introduced zinc into titanium coating. The physical morphology, biocompatibility, ability, and osteogenic effect zinc-containing coatings were investigated. ions was determined, intrinsic link between angiogenesis osteogenesis under Zinc-containing coating prepared...
Aiming to solve the problems of excessive straw residue and large soil loss in seeding belt row-sorting operation when full volume is crushed returned field northeastern region China, an active spiral pushing device (ASPSRD) was designed this paper. The on surface land collected stirred by high-speed rotating spiral-notched blades pushed non-seeding area for purpose cleaning belt. parameters key components were determined through theoretical analysis. orthogonal combination test method four...
This study developed a chain counter-rotating trenching and backfilling device to reduce high tillage resistance in orchard operations. A 3D mathematical model of the blade was created using Cartesian coordinate transformation. Taking curvature (β), curve angle (α), bend radius (R), cone residual (θ) as experimental factors, soil cutting evaluation index. The optimized parameters were β=95°, α=10°, R=24 mm, θ=39°. Bench tests performed with optimal parameters, results showed that ditching...
For Motor Imagery (MI) signals based on Brain-Computer Interface (BCI), user intentions are transformed into with specific frequencies that reflect motor identities. However, it is difficult to classify MI-EEG due their non-stationarity and low signal-to-noise ratio. In this study, we proposed a signal preprocessing method the Short-Time Fourier Transform (STFT), which has high time frequency resolution extract detailed information from signals. Furthermore, constructed hybrid model combines...
Advanced oxidation technologies that utilise sulfate radicals (·SO4-) hold significant potential for wastewater treatment applications. Employing photogenerated electrons of semiconductor to activate the persulfate system is possible enhance efficiency charge separation in photocatalysts and improve photocatalytic ability. This study aims further metal-free porphyrin supramolecular develop environmentally friendly catalysts activating peroxydisulfate (PDS). Specifically, performance a...
Although intervertebral disc degeneration (IDD) can be described as different stages of change through biological methods, this long and complex process cannot defined in by single or simple combination techniques. Under the background development nuclear magnetic resonance (NMR) technology emerging metabonomics, we based on animal models expanded to study clinical human models. The characteristics IDD were analyzed omics. Omics imaging combined with histology, cytology, proteomics was used...
It is well established that discogenic low back pain (DLBP) often caused by the inflammatory response during intervertebral disc degeneration (IDD). However, it remains unclear how mediators such as Interleukin-6 (IL-6) are involved in and (IVD) metabolism. The purpose of this study to relationship between IL-6 Transmembrane protein 100 (TMEM100), analyze different metabolites metabolic pathways various rat discs metabonomics. We a model IDD-DLBP punctures PBS infusion examine behaviors....
Abstract In recent years, topological insulators have been widely designed to manipulate various types of classical waves. The edge states characterized by defect and backscattering immunity show great application potential in energy harvesting. This work reports a spin-locked surface wave channel, which consists concrete-filled steel tubes (CFST) placed on foundation soil. Here, the distance between lattice center CFST controls hopping strength adjacent atoms, determining phase transition....
The low-temperature cracking performance of asphalt is considered one the main deteriorations in pavements. However, there have been few studies on under heat and light together. Hence, ductility test, bending beam rheometer (BBR) composition analysis test are combined to investigate together based climatic conditions China. styrene-butadiene-styrene block copolymer (SBS)-modified binders were prepared with different modifier types base this research. results show that resistance reduces It...
Abstract There is a lack of effective programmed cell death protein 1 (PD-1)‐targeted immunotherapy with good tolerability in patients advanced hepatocellular carcinoma (HCC) and severely compromised liver function. We assessed patient outcomes after combined camrelizumab molecular targeted therapy multicenter cohort study China. The included 99 HCC (58 Child-Pugh A 41 B), 84 them received from January 10, 2019, to March 31, 2021. Overall survival (OS), progression-free (PFS), objective...
Abstract Liver fibrosis is caused by chronic liver injury. There are limited treatments for it, and the pathogenesis unclear. Therefore, there an urgent need to explore of fibrosis, try identify new potential therapeutic targets. For this study we used carbon tetrachloride abdominal injection induced animal model in mice. Primary hepatic stellate cell isolation was performed a density‐gradient separation method, followed immunofluorescence stain analyses. Signal pathway analysis...
Purpose Limited use of Internet Things (IoT) technology on construction sites has restricted its value in the industry. To propel widespread application, this paper explores influencing factors and action paths companies' IoT adoption behavior. Design/methodology/approach First, literature research, theories, semi-structured expert interviews were employed to build model. Second, a questionnaire survey was conducted among Chinese contractors collect empirical data. Third, structural equation...