A5101607108- Spine and Intervertebral Disc Pathology
- Advanced Fiber Optic Sensors
- Advanced biosensing and bioanalysis techniques
- Musculoskeletal pain and rehabilitation
- Perovskite Materials and Applications
- Analytical Chemistry and Sensors
- Pesticide Residue Analysis and Safety
- Analytical chemistry methods development
- Electrochemical sensors and biosensors
- Solid-state spectroscopy and crystallography
- Spinal Fractures and Fixation Techniques
- MicroRNA in disease regulation
- Pain Mechanisms and Treatments
- Extracellular vesicles in disease
- Advanced Photonic Communication Systems
- Cancer-related molecular mechanisms research
- Plasmonic and Surface Plasmon Research
- Medical Imaging and Analysis
- Pesticide and Herbicide Environmental Studies
- Environmental Toxicology and Ecotoxicology
- Cervical and Thoracic Myelopathy
- Circular RNAs in diseases
- Nanoplatforms for cancer theranostics
- Insect and Pesticide Research
- Pharmaceutical and Antibiotic Environmental Impacts
Qingdao University
2008-2025
Affiliated Hospital of Qingdao University
2019-2025
China Southern Power Grid (China)
2025
University of Science and Technology Beijing
2023-2024
Southern University of Science and Technology
2023-2024
Jiyang College of Zhejiang A&F University
2022
Liaocheng University
2019-2021
Xiangya Hospital Central South University
2017-2021
Central South University
2017-2021
Soil and Fertilizer Institute of Hunan Province
2019
Present study demonstrates the fiber-optic localized surface plasmon resonance (LSPR) based sensitive biosensor for detection of Shigella bacterial species. The proposed sensor is comprised multi-core fiber (MCF) having seven cores arranged in a hexagonal shape and spliced with single-mode (SMF) efficient detection. An increase evanescent waves (EWs) coupling modes between MCF was achieved by etching process controlled manner. also increases refractive index sensitivity (RIS) sensor....
In this work, a localized plasmon-based sensor is developed for para-cresol (p-cresol) - water pollutant detection. A nonadiabatic [Formula: see text] of tapered optical fiber (TOF) has been experimentally fabricated and computationally analyzed using beam propagation method. For optimization sensor's performance, two probes are proposed, where probe 1 immobilized with gold nanoparticles (AuNPs) 2 the AuNPs along zinc oxide (ZnO-NPs). The synthesized metal nanomaterials were characterized by...
Acute traumatic spinal cord injury is a devastating event without effective therapeutic approach. The feeble plasticity of microvascular endothelial cells (SCMECs) after trauma one the major causes for exacerbation injury. Therefore, improving and regeneration SCMECs crucial to promote recovery For present study, we explored influence exosomes derived from neural stem (NSCs-Exos) on determined underlying mechanisms. After primary NSCs were extracted, isolated conditioned medium used...
In this work, tapered/etched multicore fiber (MCF) probes are spliced with multimode (MMF) to fabricate the sensor structure. To improve sensitivity, gold nanoparticles (AuNPs) and molybdenum disulfide (MoS <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -NPs) used immobilize both probes. Synthesized AuNPs )-nanoparticles (NPs) have peak absorption wavelengths of 519 330 nm, respectively. High-resolution transmission electron microscopy...
Double perovskites (DP) have attracted extensive attention due to their rich structures and wide application prospects in the field of optoelectronics. Here, we report 15 new Bi-based double perovskite derived halides with general formula A2 BBiX6 (A=organic cationic ligand, B=K or Rb, X=Br I). These materials are synthesized using organic ligands coordinate metal ions a sp3 oxygen, diverse structure types been obtained distinct dimensionalities connectivity modes. The optical band gaps...
Abstract Atherosclerosis is one of the leading causes death worldwide. miR-26 a potential biomarker atherosclerosis. Standardized diagnostic tests for (MIR26-DX) have been developed, but fastest progress has in predicting efficacy IFN-α therapy hepatocellular carcinoma (HCC, phase 3). MiR-26 slows atherosclerosis development by suppressing ACC1/2, ACLY, ACSL3/4, ALDH3A2, ALPL, BMP2, CD36, COL1A1, CPT1A, CTGF, DGAT2, EHHADH, FAS, FBP1, GATA4, GSK3β, G6PC, Gys2, HMGA1, HMGB1, LDLR, LIPC,...
In this paper, a tapered optical fiber-based sensor is developed for the detection of uric acid (UA) in human serum. The fiber probes were fabricated using single-mode (SMF) with taper diameter 40 μm. section has culminated on basis excretion evanescent waves and their handling capacity. To enhance sensitivity, (sensing region) was immobilized synthesized gold nanoparticles (AuNPs). AuNPs used to initiate excitation surface plasmons (SP) at ultimately leads localized plasmon resonance (LSPR)...
A highly sensitive and selective optical fiber-based enzymatic biosensor has been proposed in the present studyfor detection of uric acid (UA) human serum. The working mechanism sensor depends on surface plasma property localized plasmon resonance technique. For this purpose, a micro-ball fiber probe 350 μm diameter was fabricated using advanced fusionsplicer coated with gold nanoparticles (AuNPs) graphene oxide (GO) order to enhance its sensitivity. UV-Visible spectrophotometer...
The regeneration of the blood vessel system post spinal cord injury (SCI) is essential for repair neurological function. As a significant means to regulate gene expression, epigenetic regulation angiogenesis in SCI still largely unknown. Here, we found that Ubiquitously Transcribed tetratricopeptide repeat on chromosome X (UTX), histone H3K27 demethylase, increased significantly endothelial cells SCI. Knockdown UTX can promote migration and tube formation cells. specific knockout enhanced...
In this work, a photosensitive (PS) optical fiber-based Mach-Zehnder interferometer (MZI) structure is developed to diagnose the presence of collagen-IV in human bodies. The MZI fabricated by sequentially splicing single mode-multimode-photosensitive-multimode mode (SMPMS) fiber segments. sensing region created partially removing cladding using 40% hydrofluoric (HF) acid and depositing layers highly reflective metal nanoparticles (NPs) over it. used NPs are polyvinyl alcohol stabilized...
Homosapien collagen beta (1-O) galactosyl transferase 2 (COLGALT2) is an important enzyme during glycosylation, yet its biological functions in cancer are incompletely understood. Our previous study revealed that the osteosarcoma microenvironment, adipose-derived mesenchymal stem cells (ADSCs) demonstrate cancer-promoting effects, but exact mechanisms remain unclear. The aim of this was to investigate role COLGALT2 osteosarcoma-fostering effects ADSCs.
Low back pain (LBP) is one of the top three causes disability in developed countries, and intervertebral disc degeneration (IDD) a major contributor to LBP. In process IDD, there gradual decrease nucleus pulposus cells (NPCs) extracellular matrix (ECM). Exosomes are important exocrine mediators stem that can act directly on for tissue repair regeneration. this study, we determined antisenescence, cell proliferation promotion, ECM modulation effects human urine-derived (USC) exosomes...
Abstract The ascorbic acid (AA) is a biomarker that can be used to detect the symptoms of severe disorders such as scurvy, Parkinson’s, Alzheimer’s, and cardiovascular diseases. In this work, simple effective sensor model developed diagnose presence AA samples. To develop sensor, tapered single-mode optical fiber has been with well-known phenomenon localized surface plasmon resonance (LSPR). For LSPR, region immobilized synthesized gold nanoparticles (AuNPs) zinc oxide (ZnO-NPs) whose...
Objective. This study is aimed at determining the effects of human urine-derived stem cell-derived exosomes (USCs-exos) on pressure-induced nucleus pulposus cell (NPC) apoptosis and intervertebral disc degeneration (IDD) ERK AKT signaling pathways. Methods. The NPCs were obtained from patients with herniated lumbar discs. Western blot analysis (WB) quantitative real-time polymerase chain reaction (qRT-PCR) used to determine endoplasmic reticulum (ER) stress levels under stress. Human USCs...
Abstract 0D organic–inorganic antimony halides have attracted increasing attention due to the non‐toxicity, high stability, and superior photoluminescence quantum yield (PLQY). Here, a series of hybrid chlorides with same organic cation ethyltriphenylphosphonium (Ph 3 EtP + ), including non‐emissive EtP) 2 Sb Cl 8 nine SbCl 5 ‐based emissive compounds, are synthesized characterized. These compounds namely, guest‐free ·guest (guest = glycol, acetic acid, methanol, ethanol, n‐propanol,...
Flexible interconnected multi-district grid operation will be the development trend of Southern Power Grid. In view difficulty existing flexible control technology to meet demand and security stability under new type electric power system, study based on flexibility initiative support technology, put forward whole area project in Guangdong, South Guangdong other projects have been successfully implemented, which greatly enhance economy, partitioned operation, promote construction "reasonable...
Low back pain (LBP) resulting from sciatic nerve compression presents major challenges in management, as traditional therapies provide only short-term relief and pose risks of systemic toxicity. In this study, an innovative Fe3O4@ZIF-8-RVC (FZR) dual-responsive nanoplatform is introduced that integrates magnetic targeting with pH-sensitive, sustained drug release to overcome these limitations. The FZR encapsulates ropivacaine (RVC) within the ZIF-8-coated Fe3O4 core, enabling precise...