A5101578619- Chromosomal and Genetic Variations
- Genetic diversity and population structure
- CRISPR and Genetic Engineering
- Genomics and Phylogenetic Studies
- Fish Biology and Ecology Studies
- Fish Ecology and Management Studies
- Animal Genetics and Reproduction
- Solar Energy Systems and Technologies
- Phase Change Materials Research
- Biological and pharmacological studies of plants
- Solar Thermal and Photovoltaic Systems
- Computational Drug Discovery Methods
- Genetic Mapping and Diversity in Plants and Animals
- Identification and Quantification in Food
- HER2/EGFR in Cancer Research
- Respiratory viral infections research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Plant Virus Research Studies
- Genomics and Chromatin Dynamics
- Plant and animal studies
- Plant tissue culture and regeneration
- Cancer-related molecular mechanisms research
- Melanoma and MAPK Pathways
- Remote Sensing and Land Use
- Environmental DNA in Biodiversity Studies
Yunnan University
2012-2024
Changsha University of Science and Technology
2022-2023
Sichuan University
2022
Center for Life Sciences
2019
Nanjing Normal University
2012-2015
Northwest A&F University
2013
Chinese Academy of Sciences
2006
University of Konstanz
2005-2006
Institute of Hydrobiology
2006
University of Würzburg
2005
Abstract Common carp ( Cyprinus carpio ) is an allotetraploid species derived from recent whole genome duplication and provides a model to study polyploid evolution in vertebrates. Here, we generate three chromosome-level reference genomes of C. compare related diploid Cyprinid genomes. We identify Barbinae lineage as potential progenitor then divide the into two subgenomes marked by distinct similarity progenitor. estimate that progenitors diverged around 23 Mya merged 12.4 based on...
Significance Why is polyploidization rarer in animals than plants? This question remains unanswered due to the absence of a suitable system for studying instantaneous and crucial changes that immediately follow hybridization. RNA-seq analyses discover extensive chimeric genes immediate mutations orthologs both diploid tetraploid offspring goldfish (♀) × common carp (♂) hybrids. Overall, show paternal-biased expression, yet tetraploids maternal-biased expression. Some differentially expressed...
VennPainter is a program for depicting unique and shared sets of genes lists generating Venn diagrams, by using the Qt C++ framework. The software produces Classic Venn, Edwards' Nested diagrams allows eight in graph mode 31 data processing only. In comparison, previous programs produce allow maximum six sets. incorporates user-friendly features works Windows, Linux Mac OS. Its graphical interface does not require user to have programing skills. Users can modify diagram content up datasets...
A persistent enigma is the rarity of polyploidy in animals, compared to its prevalence plants. Although animal polyploids are thought experience deleterious genomic chaos during initial polyploidization and subsequent rediploidization processes, this hypothesis has not been tested. We provide an improved reference-quality de novo genome for allotetraploid goldfish whose origin dates ~15 million years ago. Comprehensive analyses identify changes subgenomic evolution from asymmetrical...
• Ten kinds of Trombe wall systems integrated with PCMs were proposed. The effect on thermal comfort PCM temperature and location was analyzed. indoor discomfort hour degree-hour calculated. An optimal structure obtained for the hot summer cold winter region. phase change materials (PCMs) are two effective ways to regulate comfort. However, surfers from overheating in suffer low heat transfer rate caused by limited conductivity. To compensate shortcomings methods, this paper proposed a...
Historical drainage patterns adjacent to the Qinghai-Tibetan Plateau differed markedly from those of today. We examined relationship between history and geographic genetic variation in Yunnan spiny frog, Nanorana yunnanensis, using approximately 981 base pairs mitochondrial DNA partial sequences protein-coding genes ND1 ND2, intervening areas including complete tRNAIle, tRNAGln tRNAMet. Two null hypotheses were tested: (i) that do not correspond development systems (ii) populations had been...
Abstract Aim We sought to reconstruct the spatio‐temporal genetic diversification in goldfish of Carassius auratus complex, which is widely distributed Eurasia, test whether vicariance events or human‐mediated translocations best explained lineage divergence and genogeographical history. Location East Asia Oriental islands including Japan, Ryukyus Taiwan, Europe, Russia Czech Republic. Methods reconstructed matrilineal history Eurasian using 1876 sequences from partial mitochondrial DNA...
Background Goldfish, Carassius auratus, have experienced strong anthropogenic selection during their evolutionary history, generating a tremendous extent of morphological variation relative to that in native Carassius. To locate the geographic origin goldfish, we analyzed nucleotide sequences from part control region (CR) and entire cytochrome b (Cytb) mitochondrial DNA genes for 234 goldfish large series specimens. Four important characteristics used taxonomy–body shape, dorsal fin, eye...
Abstract Determining the functional consequences of karyotypic changes is invariably challenging because evolution tends to obscure many its own footprints, such as accumulated mutations, recombination events, and demographic perturbations. Here, we describe assembly a chromosome-level reference genome gayal (Bos frontalis) thereby revealing structure, at base-pair-level resolution, telo/acrocentric-to-telo/acrocentric Robertsonian translocation (2;28) (T/A-to-T/A rob[2;28]). The absence any...
Abstract Hybridization and polyploidization are considered important driving forces that form new epigenetic regulations. To study the changing patterns of expression accompanying hybridization polyploidization, we used RNA-seq qRT-PCR to investigate global homoeologue in diploid tetraploid hybrids Carassius auratus red var. (♀) (R) Cyprinus carpio (♂) (C). By comparing relative levels between their parents, defined level dominance (ELD) bias (HEB) liver tissue. The results showed...
The knowledge of understanding the molecular traits sterile triploid fish is sparse. Herein, we analyzed microRNA (miRNA) alternations in testes produced by crossing tetraploid with diploid fish, compared those tetraploids and diploids used as controls. A total 136, 134, 142 conserved miRNAs 105, 112, 119 novel were identified diploid, triploid, respectively. genes targeted differentially expressed enriched GO term cell surface receptor signaling pathway, cellular process, G-protein coupled...
The evolution of the Yunnan Plateau's drainages network during Pleistocene was dominated by intense uplifts Qinghai-Tibetan Plateau. In present study, we investigated association between evolutionary histories three main drainage systems and geographic patterns genetic differentiation Poropuntius huangchuchieni.We sequenced complete sequences mitochondrial control region for 304 specimens Cytochrome b gene 15 species P. huangchuchieni 5 opisthoptera. Phylogenetic analysis identified five...
Protein kinases become an important source of potential drug targets. Developing new, efficient, and safe small-molecule kinase inhibitors has topic in the field research development. In contrast with traditional wet experiments which are time-consuming expensive, machine learning-based approaches for predicting small molecule protein time-saving cost-effective, highly desired us. However, issue sample scarcity (known active inactive compounds usually limited most kinases) poses a challenge...
Male swordtails in the genus Xiphophorus display a conspicuous ventral elongation of caudal fin, sword, which arose through sexual selection due to female preference. Females mate regularly and are able store sperm for at least 6 months. If multiple mating is frequent, this would raise intriguing question about role choice male-male competition shaping system these fishes. Size-dependent alternate strategies occur Xiphophorus; one such strategy courtship with sigmoid by large dominant males,...
The identification of allopolyploidization events benefits from molecular dating and divergence assessments progenitor genomes. Information on gene duplications only, either orthologs or paralogs, provides incomplete information. Analyses mitochondrial DNA yield insights into matrilineal history, which may differ patrilineal evolution. Two important food pet fishes, the common carp (Cyprinus carpio) goldfish (Carassius sp.), appear to have experienced allotetraploidization sometime 12 20...
Abstract A tetraploidization event took place in the cyprinid lineage leading to goldfishes about 15 million years ago. PCR survey for Hox genes goldfish Carassius auratus (Actinopterygii: Cyprinidae) was performed assess consequences of this genome duplication. Not surprisingly, genomic organization gene clusters is similar that closely related zebrafish ( Danio rerio ). However, exhibits a much larger number recent pseudogenes, which are characterized by indels. These findings consistent...
Pliocene uplifting of the Qinghai-Tibetan Plateau (QTP) and Quaternary glaciation may have impacted Asian biota more than any other events. Little is documented with respect to how geological climatological events influenced speciation as well spatial genetic structuring, especially in vertebrate endotherms. Macaca mulatta most widely distributed non-human primate. It be suitable model test hypotheses regarding consequences orogenesis on an endotherm.Using a large dataset maternally...
The phylogenetic relationships of Asian schilbid catfishes the genera Clupisoma, Ailia, Horabagrus, Laides and Pseudeutropius are poorly understood, especially those Clupisoma. Herein, we reconstruct phylogeny 38 species belonging to 28 14 families using concatenated mitochondrial genes COI, cytb, 16S rRNA, as well nuclear RAG1 RAG2. resulting trees consistently place Clupisoma sister taxon Laides, five representative form two monophyletic groups with (Ailia (Laides, Clupisoma)) (Horabagrus,...
Abstract A goldfish ( Carassius auratus ) bacterial artificial chromosome genomic library (BAC library) was constructed from one aquarium‐bred male specimen (tetraploid, 4 n =100, genome size=3.52 pg/cell). The consists of 128,352 positive clones with an average insert size 150.4 kb, covering the 11‐fold. All were spotted onto nylon filters and thus are available for screening regions interest, such as candidate genes, gene families, or large‐sized syntenic DNA cyprinid species. Preliminary...