A5100701821- Circular RNAs in diseases
- Esophageal Cancer Research and Treatment
- Insect Resistance and Genetics
- Soybean genetics and cultivation
- CRISPR and Genetic Engineering
- RNA modifications and cancer
- Health, Environment, Cognitive Aging
- Machine Learning in Bioinformatics
- Gastric Cancer Management and Outcomes
- Connexins and lens biology
- MicroRNA in disease regulation
- Cell Adhesion Molecules Research
- Cancer-related molecular mechanisms research
- Neonatal Respiratory Health Research
- Neurobiology and Insect Physiology Research
- Gastrointestinal Tumor Research and Treatment
- Genetics, Aging, and Longevity in Model Organisms
- Biochemical effects in animals
- Nitrogen and Sulfur Effects on Brassica
- Effects of Environmental Stressors on Livestock
- Congenital heart defects research
- Insect-Plant Interactions and Control
- Intelligent Tutoring Systems and Adaptive Learning
- Inhalation and Respiratory Drug Delivery
- Transgenic Plants and Applications
The Affiliated Yongchuan Hospital of Chongqing Medical University
2025
Chongqing Medical University
2025
Swinburne University of Technology
2024
University of Maryland Eastern Shore
2023
Nanjing Medical University
2017-2023
Jiangsu Provincial Center for Disease Control and Prevention
2023
Zhejiang Provincial People's Hospital
2021
Jilin Agricultural University
2021
Peking University First Hospital
2021
Peking University
2021
Laminins, the main components of basement membranes, are heterotrimers consisting α, β, and γ polypeptide chains linked together by disulfide bonds. Laminins-1 -2 both composed β1 γ1 differ from each other on their α chain, which is α1 α2 for laminin-1 -2, respectively. The present study shows that whereas laminins-1 synthesized in mouse developing lung epithelial–mesenchymal cocultures derived it, epithelial mesenchymal monocultures lose ability to synthesize laminin chain. Synthesis chain...
Persistent infection with high-risk human papillomavirus (HR-HPV) is a known pathogenic factor of cervical cancer. To develop scientific guidance for cancer screening and HPV vaccination, we analyzed genotypes in Suzhou City, China. This study utilized data from the project 2016 to 2021. A total 444,471 female residents who voluntarily underwent testing were included study. The overall HR-HPV prevalence was 10.2%. three most common HPV52 (2.81%), HPV58 (1.64%), HPV16 (1.46%). rate increased...
Ferroptosis induced by iron accumulation can disrupt the physiological functions of bone marrow mesenchymal stem cells (BMSCs). BMP9 is an effective osteogenic factor. However, role and its molecular mechanisms in osteoporosis remain unclear. This study aims to explore mechanism alleviating osteoporosis. Clinical samples were collected analyze relationship between The effect on lipid peroxidation levels BMSCs under conditions was assessed using C11-BODIPY staining, MitoSOX MDA SOD activity...
purpose. The βB2-crystallin gene (Crybb2) is expressed at an increasing level in the postnatal lens cortex. It has been assumed that functions as structural protein, although this not directly tested. Here vivo of are examined via generation mice with a targeted disruption Crybb2. methods. Gene targeting embryonic stem cells was used to generate mouse lines which Crybb2 deleted. structure and protein expression were analyzed by PCR, immunoblot, two-dimensional gel electrophoresis. Knockout...
Gracilariopsis lemaneiformis ( G. ) is an important marine red macroalgae with high economic and ecological value all over the world. To date, global warming a key issue that has great impact on living organisms, such as macroalgae. L-arginine (Arg) precursor of nitric oxide (NO) polyamines (PAs), which can induce stress defense responses in land plants. However, its role inducing algae resistance at temperature (HT) unclear. In this study, thalli were treated different concentrations Arg to...
To increase the expression efficiency of Bt gene in transgenic poplar and expand insect resistance spectrum, Cry1Ac Cry3A were simultaneously constructed two different plant transformation vectors. Two genes on vector p71A68Y71 separately driven by promoters CAMV35S CoYMV, a matrix attachment region (MAR) sequence was added to both sides; contrast, p05A68A71 promoter without MAR structure. With agrobacterium mediation method, vectors transformed high-quality hybrid clone Juba Populus...
Barrett's esophagus (BE) is defined as a metaplasia condition in the distal esophagus, which native squamous epithelium lining replaced by columnar with or without intestinal metaplasia. It commonly accepted that BE precancerous lesion for esophageal adenocarcinoma. The aim of this study was to investigate aberrant microRNAs (miRNAs) and differentially expressed genes (DEGs) associated based on online microarray datasets. One miRNA five gene expression profiling datasets were retrieved from...
Accumulating evidence highlights the important role of long non-coding RNAs (lncRNAs) in a large number biological processes. However, knowledge genome scale expression lncRNAs and their potential function gastric cancer is still lacking. Using RNA-seq data from 420 patients The Cancer Genome Atlas (TCGA), we identified 1,294 differentially expressed compared with adjacent normal tissues. We also found 247 between intestinal subtype diffuse subtype. Survival analysis revealed 33...
Abstract Background Circular RNAs (circRNAs) are emerging as crucial regulators in various human diseases. So far, the expression profile and regulatory mechanism of circRNAs postmenopausal osteoporosis (PMOP) less studied should be deciphered urgently. Herein, we aimed to reveal key affecting PMOP clarify their compounding actions. Methods To actions, whole transcriptome sequencing bioinformatics analysis were performed identify differentially expressed (DECs). The pattern networks DECs...
Children with special health care needs (CSHCNs) are at an increased risk of vaccine-preventable infections (VPDs), but they also face the dilemma vaccine hesitancy. We obtained information on pediatric visits from Referral and Assessment Information System for Vaccination (RAISV) vaccination Jiangsu Province Immunization (JSIIS). followed occurrence Adverse Events Following (AEFIs) VPDs by actively calling querying China Disease Control Prevention (CISDCP). The Poisson test was used to...
The current study aimed to examine the anatomical structure of hepatic vein segment IV liver (S4) using three-dimensional (3D) visualization technology in order explore surgical value middle (MHV) manipulation and highlight importance research surgery.
Abstract Eotetranychus kankitus is an important mite pest in citrus, but molecular data on the developmental processes of E. are lacking. The different development stages mix was used to sequence for transcriptome and small RNAs identify genes predict miRNAs associated with sesquiterpenoid ecdysteroid biosynthesis signaling pathways. More than 36 million clean reads were assembled 67,927 unigenes generated. Of unigenes, 19,300 successfully annotated through annotation databases NR,...
INTRODUCTIONConcerning the course and distribution of bronchial arteries in lung, Miller claimed that bronchi both sides have two to three running on their posterior wall, giving off branches accompanying tree. They can be traced down very minute