A. Roy

ORCID: 0000-0002-4515-7365
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About
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Research Areas
  • COVID-19 epidemiological studies
  • COVID-19 Pandemic Impacts
  • Effects of Environmental Stressors on Livestock
  • Congenital Anomalies and Fetal Surgery
  • Respiratory Support and Mechanisms
  • Quantum and electron transport phenomena
  • Digital Imaging for Blood Diseases
  • Genetic and phenotypic traits in livestock
  • Reproductive Physiology in Livestock
  • CAR-T cell therapy research
  • Meat and Animal Product Quality
  • Cardiac pacing and defibrillation studies
  • Cardiac and Coronary Surgery Techniques
  • Cancer Immunotherapy and Biomarkers
  • Livestock Management and Performance Improvement
  • Salivary Gland Disorders and Functions
  • Electrospun Nanofibers in Biomedical Applications
  • Ruminant Nutrition and Digestive Physiology
  • COVID-19 Digital Contact Tracing
  • Magnetic properties of thin films
  • Reproductive Health and Contraception
  • Malaria Research and Control
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Mosquito-borne diseases and control
  • Animal Diversity and Health Studies

Patuakhali Science and Technology University
2024

Centre Hospitalier de l’Université de Montréal
2024

Banaras Hindu University
2020-2022

Bristol-Myers Squibb (United States)
2020

Bristol-Myers Squibb (Germany)
2018

National Institute of Technology Durgapur
2017

Netaji Subhash Chandra Bose Medical College
2016

Advanced Bioscience Laboratories (United States)
2012

Institute for Bioscience and Biotechnology Research
2012

University of Maryland, College Park
2012

A nivolumab monotherapy flat-dosing regimen of 480 mg every 4 weeks (Q4W) has been approved in several markets, including the United States, Canada, and European Union, as an alternative dosing for indications. Approvals this Q4W were based on population pharmacokinetic (PK) analyses, established flat exposure-response relationships, clinical safety. The objective study was to compare PK exposure with 3 mg/kg 2 (Q2W) 240 Q2W using modeling simulation, evaluate safety regimen.Nivolumab...

10.1093/annonc/mdy408 article EN cc-by-nc Annals of Oncology 2018-09-11

Nivolumab 480 mg every 4 weeks (Q4W) is approved in the European Union, United States, and several other markets across multiple tumor types. Its approval was supported by quantitative efficacy/safety analyses bridging to 3 mg/kg 2 (Q2W).The benefit-risk profile of nivolumab Q4W relative Q2W evaluated using population pharmacokinetic modeling exposure-response (E-R) for safety efficacy. Pharmacokinetic exposures were predicted 3203 patients with melanoma, non-small-cell lung cancer (NSCLC),...

10.1016/j.annonc.2019.10.015 article EN cc-by-nc-nd Annals of Oncology 2020-01-06

Plasma levels of 3-methoxy-4-hydroxyphenylglycol (MHPG) were measured in 51 depressed patients and 43 normal control subjects. There significantly higher plasma MHPG the combined patient group with current or past melancholia (N = 28) than nonmelancholic 12) dysthymic 11) patients, unipolar melancholic 16) versus bipolar 4) a major depressive episode who failed to suppress cortisol after dexamethasone suppression test 24) 16). Anxiety symptoms correlated levels. These results substantiate...

10.1176/ajp.143.7.846 article EN American Journal of Psychiatry 1986-07-01

Daily new COVID-19 cases from January to April 2020 demonstrate varying patterns of SARS-CoV-2 transmission across different geographical regions. Constant infection rates were observed in some countries, whereas China and South Korea had a very low number daily cases. In fact, successfully quickly flattened their curve. To understand why this was the case, paper investigated possible aerosol-forming atmosphere relationship policy measures adopted by select countries.

10.2196/20699 article EN cc-by JMIR Public Health and Surveillance 2020-11-15

Whipple's operation consists of resection the pancreatic head and duodenum, followed by pancreaticojejunostomy, choledochojejunostomy, gastrojejunostomy or duodenojejunostomy. Indications include neoplasms periampullary region, symptomatic chronic pancreatitis, and, occasionally, trauma CT is useful in diagnosing postoperative complications detecting disease recurrence during long-term follow-up. This complex surgical procedure causes alterations normal anatomy, which may lead to difficulty...

10.2214/ajr.163.4.7916530 article EN American Journal of Roentgenology 1994-10-01

Aim: To investigate the complex interplay between human papilloma virus (HPV) infection and p53 gene alteration in 92 head neck squamous cell carcinoma (HNSCC) 28 leukoplakia samples from eastern India. Methods: DNA isolated patient was subjected to HPV detection, loss of heterozygosity (LOH) analysis chromosome 17p region harbouring , genotyping at codon 72 locus sequencing entire identify somatic mutations. Codon heterozygotes carrying mutation were further cloned resequenced allele...

10.1136/jcp.2005.034835 article EN Journal of Clinical Pathology 2006-11-01

A community survey was conducted in all adults with Down syndrome living three health districts to see if there any correlation between radiological and neurological abnormalities which could indicate the presence of atlantoaxial instability. There no difference proportion individuals group suggestive instability (6/14) compared normal X-rays (50/123) as determined by chi square test (0.01463: not significant). The clinical ethical implications for screening people are discussed view these findings.

10.1177/014107689008300708 article EN Journal of the Royal Society of Medicine 1990-07-01

We report measurements of the magnetization insulating phosphorus-doped silicon for fields up to 50 kG and temperatures down 1.25 K, dopant concentrations N=6.7\ifmmode\times\else\texttimes\fi{}${10}^{17}$ 2.8\ifmmode\times\else\texttimes\fi{}${10}^{18}$ ${\mathrm{cm}}^{\mathrm{\ensuremath{-}}3}$. The data are found be in quantitative agreement with a generalization, finite fields, scaling calculation magnetic properties phase, support model hierarchically coupled spin pairs.

10.1103/physrevb.34.387 article EN Physical review. B, Condensed matter 1986-07-01

Few studies have been made of the effects gonadotrophic stimulation ovary goat during anoestrous season (roughly March to September). Such reports as appeared [Stevenson, 1938; Sandburg, 1942; Phillips, Simmons & Schott, 1943; Hammond Jnr., Frank, Schott Simmons, 1945], are concerned mainly with attempts cause goats, by treatment pregnant mares' serum gonadotrophin (p.m.s.), kid down in autumn, thus ensuring a good yield milk winter. The present paper quantitative data on follicular growth...

10.1677/joe.0.0060121 article EN Journal of Endocrinology 1949-10-01

We have made static susceptibility measurements at temperatures between 1.25 and 300 K on samples of phosphorus-doped silicon with dopant concentrations in the range 0.2/${n}_{c}$1.3, where ${n}_{c}$ is critical concentration for metal-insulator transition. In this paper we discuss our results diamagnetism associated donor electrons. find that above 60 diamagnetic varies linearly concentration. associate observed these a term, ${\ensuremath{\chi}}_{D}$(T,n), which Landau-Peierls-Pauli type,...

10.1103/physrevb.37.5522 article EN Physical review. B, Condensed matter 1988-04-01

10.1016/0038-1098(86)90728-3 article EN Solid State Communications 1986-11-01

Abstract Occurrence of yellow vein mosaic disease mesta ( Hibiscus cannabinus L. and H. sabdariffa L.) was found to be endemic in parts India. For rapid sensitive diagnosis the Begomovirus associated with this disease, a radiolabelled diagnostic method has been developed. Southern hybridization nucleic acid spot using probes coat protein (CP) gene DNA A β virus were able detect both plants viruliferous whiteflies. These detected presence same experimentally infected Vigna showing only leaf...

10.1111/j.1439-0434.2007.01296.x article EN Journal of Phytopathology 2007-08-13

  The aim of this study was to identify the deficiency uridine monophosphate synthase (DUMPS) and complex vertebral malformation (CVM) in Iranian Holstein bulls. A total 144 blood samples were prepared bulls Abbas Abad Animal Breeding Center Ferdowsi University Mashhad's Dairy Farm Khorasan state Iran. Genomic PCR-RFLP protocol performed amplify polymorphic region bovine UMPS gene. Also, genomic PCR-SSCP method for CVM solute carrier family 35 member 3 (SLC35A3) genes. results...

10.5897/ajb09.334 article EN cc-by AFRICAN JOURNAL OF BIOTECHNOLOGY 2009-11-16

The resistivity and the Hall coefficient of indium-doped cadmium selenide with carrier concentrations spanning insulator-to-metal transition have been measured as a function temperature. We demonstrate that use mobility deduced from these data careful analysis application recent theory yield an estimate degree compensation, K=${N}_{A}$/${N}_{D}$, for metallic well insulating material. Combining results measurements at room temperature, one can then both number donors, ${N}_{D}$, acceptors,...

10.1103/physrevb.38.3323 article EN Physical review. B, Condensed matter 1988-08-15
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