A5000128079- Invertebrate Immune Response Mechanisms
- Aquaculture disease management and microbiota
- Neurobiology and Insect Physiology Research
- Insect symbiosis and bacterial influences
- Vibrio bacteria research studies
- Galectins and Cancer Biology
- Signaling Pathways in Disease
- Macrophage Migration Inhibitory Factor
- Glycosylation and Glycoproteins Research
- Studies on Chitinases and Chitosanases
- Crustacean biology and ecology
- Parasite Biology and Host Interactions
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Carbohydrate Chemistry and Synthesis
- Immune cells in cancer
Universidad Nacional Autónoma de México
2014-2024
Institut Cochin
2020
Université Paris Cité
2020
Inserm
2020
Centre National de la Recherche Scientifique
2020
Several lectins have been found in crustaceans, and it has suggested that they play roles cell signalling, cell–cell interaction, protein synthesis pathogen recognition. These functions are performed through their specificity for carbohydrates. This review analyses the carbohydrate specificity, tissue distribution participation immune responses of crustaceans. Furthermore, we explore some data showing lectin expression seems to be stimulated by pathogens, favouring crustacean survival.
Abstract Glycosylation with O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a reversible posttranslational modification that regulates the activity of intracellular proteins according to glucose availability and its metabolism through hexosamine biosynthesis pathway. This has been involved in regulation various immune cell types, including macrophages. However, little known concerning mechanisms regulate protein O-GlcNAcylation level these cells. In present work, we demonstrate LPS...
Galectins are a group of β-galactoside-binding lectins associated with regulating immunological response. In the brains AD patients and 5xFAD (familial AD) mice, galectin-3 (Gal-3) was highly upregulated found to be expressed in microglia Aβ plaques. However, participation other galectins, specifically galectin-9 (Gal-9) T-cell immunoglobulin mucin domain 3 (Tim-3) receptors, unknown inflammatory The experimental model
The crustacean haemolymph contains three main cell populations; however, it is not clear which mechanisms participate in the regulation of cells related to innate immunity. This work aimed identify potential interleukin-like receptors that could regulate cellular responses Cherax quadricarinatus. By histochemical analysis with murine anti-CD25 staining (targeting α-chain IL-2 receptor), we identified this antibody recognizes cytoplasmic granules semigranular and granular haemocytes. In...
PirAB is a binary protein complex secreted by specific strains of Vibrio parahaemolyticus (Vp) that harbor the pVA1 virulence plasmid and express PirAVp PirBVp toxins. PirABVp causes acute hepatopancreatic necrosis disease (AHPND), newly emergent penaeid shrimp can cause 70–100% mortality has resulted in great economic losses since its appearance. The cy-totoxic effect on epithelial cell hepatopancreas been extensively reported. Our studies found subunit lectin activity recognizes...
The prawn Macrobrachium tenellum shows aquaculture potential due to its well-defined reproductive cycle linked female nutritional requirements. Significant changes occur in egg composition during the 16 17-day embryo development. Understanding ontogenic proteins is crucial for developmental insights and controlled reproduction. We employed free-label quantitative proteomics analyze peptides at initial final stages of wild females. Using emPAI protocol Proteome Discoverer 2.0, we identified...