A5086775674- Phytochemistry and Biological Activities
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Advanced biosensing and bioanalysis techniques
- Natural product bioactivities and synthesis
- Dental Implant Techniques and Outcomes
- Bone Tissue Engineering Materials
- Fermentation and Sensory Analysis
- RNA Interference and Gene Delivery
- Carcinogens and Genotoxicity Assessment
- Ferrocene Chemistry and Applications
- Horticultural and Viticultural Research
- Metal complexes synthesis and properties
- Natural Antidiabetic Agents Studies
- Pesticide Exposure and Toxicity
- Synthesis and Biological Evaluation
- Plant Pathogens and Fungal Diseases
- Pesticide Residue Analysis and Safety
- Biopolymer Synthesis and Applications
- Plasma Applications and Diagnostics
- Phytochemical Studies and Bioactivities
- Plant Toxicity and Pharmacological Properties
- Molecular Junctions and Nanostructures
University of Belgrade
2011-2023
Vinča Institute of Nuclear Sciences
2013-2021
Institute of Economic Sciences
2013
Mayo Clinic
2008-2012
ObjectiveAltering dysbiotic gut flora through synbiotic supplementation has recently been recognized as a potential treatment strategy to reduce the levels of gut-derived uremic toxins and decrease inflammation. Assessing its efficacy safety main goal our randomized, double-blind, placebo-controlled study.MethodsA total 34 nondialyzed chronic kidney disease patients, aged ≥18 years, with an estimated glomerular filtration rate between 15 45 mL/minute, were randomized either intervention...
Multiple sclerosis (MS) is a debilitating inflammatory disease of the central nervous system (CNS) characterized by local destruction insulating myelin surrounding neuronal axons. With more than 200 million MS patients worldwide, absence treatments that prevent progression or induce repair poses major challenge. Anti-inflammatory therapies have met with limited success only in preventing relapses. Previous screening human serum samples revealed natural IgM antibodies bind oligodendrocytes...
Gentiana lutea belonging to the Gentianaceae family of flowering plants are routinely used in traditional Serbian medicine for their beneficial gastro-intestinal and anti-inflammatory properties. The aim study was determine whether aqueous root extracts consisting gentiopicroside, gentisin, bellidifolin-8-O-glucoside, demethylbellidifolin-8-O-glucoside, isovitexin, swertiamarin amarogentin prevents proliferation aortic smooth muscle cells response PDGF-BB. Cell cell cycle analysis were...
Accumulation of intracellular sorbitol due to increased aldose reductase (ALR2) activity has been implicated in the development various secondary complications diabetes. Thus, ALR2 inhibition could be an effective strategy prevention or delay certain diabetic complications. Gentiana lutea grows naturally central and southern areas Europe. Its roots are commonly consumed as a beverage some European countries also known have medicinal properties. The water, ethanol, methanol, ether extracts G....
Fruit wines are well known for their profound health-promoting properties including both enzyme activations and inhibitions. They may act preventive in regard to diabetes melitus other chronic diseases.Potential α-glucosidase inhibitory activity of fruit made from blueberry, black chokeberry, blackberry, raspberry sour cherry was the subject this study.In order increase alcohol content due enriched extraction total phenolics, sugar added pomace half examined wine samples.Compared with...
Herbal preparation Chlamyfin was investigated for its total polyphenol content, 2,2-diphenyl-1- picrylhydrazyl (DPPH) scavenging activity, and anti-inflammatory genotoxic properties. A high content provided evidence of DPPH radical activity (IC50 = 4.96 ± 0.23 μg/ml). Analysis the electrochemical behavior indicated reducing ability, i.e., antioxidant capacity, in agreement with test. myeloperoxidase (MPO) inhibition by suggested action values 5.40 μg/ml 4.45 an incubation time 10 30 min,...
Abstract During high-temperature cooking of protein rich foods, especially meat and fish, heterocyclic aromatic amines can be formed. These are a class potent mutagens that cause alterations in the structure DNA chromosomes. In recent decades, research has been focused on investigating plants their phytochemicals as potential antimutagens. The aim this study was to examine anti-genotoxic effect methanolic root leaf extracts Gentiana lutea against food 2-amino-3-methylimidazo[4,5-f]quinoline...
Red wine is one of the most popular alcoholic beverages. Its popularity also due to fact that its components can have beneficial effects on human health when consumed in moderate amounts. Throughout history, production technology has advanced achieve a final product highest possible quality. The aim this study was assess impact melatonin addition vinification process total phenolic content Muscat Hamburg red wine. Additionally, an elemental analysis wines conducted. results indicated...
Melatonin, a hormone secreted by the pineal gland, is also found in certain seeds, leaves, and fruits, including grapes wines. It produced during vinification through yeast inoculation. Known for its various health benefits, antioxidant effects influence on polyphenol biosynthesis plants, question arises whether adding melatonin can enhance wine quality. This study aimed to investigate impact of addition total phenolic content activity Moldova red wine. Results indicated an 8% increase...
Chronic hyperglycemia in diabetes leads to macro and microvascular complications. An increase the aldose reductase (ALR2) activity, accumulation of sorbitol, advanced glycation end-products (AGEs), inflammation lead cellular damage, ultimately resulting ALR2 inhibition has been a consideration treat/manage diabetic complications, but most inhibitors are not free side effects. As part our work find better inhibitors, we found that extracts Gentiana lutea exhibited inhibitory potential vitro....