A5012793449- Venomous Animal Envenomation and Studies
- Insect and Pesticide Research
- Antimicrobial Peptides and Activities
- Animal Genetics and Reproduction
- Cholinesterase and Neurodegenerative Diseases
- Healthcare and Venom Research
- Identification and Quantification in Food
- Genomics and Chromatin Dynamics
- Plant biochemistry and biosynthesis
- Invertebrate Immune Response Mechanisms
- Computational Drug Discovery Methods
- Vector-borne infectious diseases
- Rabies epidemiology and control
- Biochemical and Structural Characterization
- Sperm and Testicular Function
- Alzheimer's disease research and treatments
- Insect and Arachnid Ecology and Behavior
- Neurobiology and Insect Physiology Research
Universidade Federal de Uberlândia
2015-2022
Snake venoms are complex mixtures mainly composed of proteins and small peptides. Crotoxin is one the most studied components from Crotalus venoms, but many other less known due to their low abundance. The venome durissus terrificus, lethal Brazilian snake, was investigated by combining its venom gland transcriptome proteome create a holistic database compounds unraveling novel toxins. We constructed cDNA library C. d. terrificus using Illumina platform through high resolution liquid...
Snakebites are a serious health problem in tropical countries. In Brazil, the genus Bothrops (Viperidae family) causes most of ophidic accidents, characterized by proteolysis and haemorrhage. Snake venoms rich sources toxins with great therapeutic biotechnological potential omics approaches is valuable tool for identification new bioactive components venom. this study, we described first transcriptome venom gland moojeni snake, using next-generation sequencing Illumina platform. We...
Animal poisons and venoms are sources of biomolecules naturally selected. Rhinella schneideri toads widespread in the whole Brazilian territory they have poison glands mucous gland. Recently, protein from toads' secretion has gaining attention. Frog skin is widely known to present great number host defense peptides we hypothesize them as well. In this study, used a RNA-seq analysis R. biochemical tests with gland unravel its molecules. Total RNA toad was extracted using TRizol reagent,...
ABSTRACT Mammalian semen chromatin comprises DNA, protamine, and, at lower levels, other proteins. This constitution confers intense compaction to the chromatin, helping protect DNA and causing head of sperm be very small, facilitating safe transport its genetic contents. It is known that changes in lead fertility problems bulls, justifying studies this structure. Although there are theoretical models because high compaction, no morphological evidence such models. The aim study was...