A5103018355- Thermochemical Biomass Conversion Processes
- Lignin and Wood Chemistry
- Hepatocellular Carcinoma Treatment and Prognosis
- Nanoplatforms for cancer theranostics
- Immune Cell Function and Interaction
- Cancer Cells and Metastasis
- Ultrasound and Hyperthermia Applications
- MRI in cancer diagnosis
- Cancer Immunotherapy and Biomarkers
- Energy and Environment Impacts
- Immunotherapy and Immune Responses
- Cancer Mechanisms and Therapy
- Immune cells in cancer
- Liver Disease Diagnosis and Treatment
- Heavy Metals in Plants
- Sirtuins and Resveratrol in Medicine
- Chromatography in Natural Products
- Microbial Metabolism and Applications
- Agronomic Practices and Intercropping Systems
- FOXO transcription factor regulation
- Genomics, phytochemicals, and oxidative stress
- Uterine Myomas and Treatments
- Flame retardant materials and properties
- Circular RNAs in diseases
- Peanut Plant Research Studies
Yunnan Agricultural University
2024-2025
Harbin Medical University
2015-2024
First Affiliated Hospital of Harbin Medical University
2015-2024
Nanchang University
2019-2024
Jinan Central Hospital
2019-2024
Shandong First Medical University
2024
State Key Laboratory of Food Science and Technology
2019-2022
Shandong University
2019
Harbin University
2018
The epithelial-to-mesenchymal transition (EMT) program is critical for epithelial cell cancer progression and fibrotic diseases. FOXO1 influences a broad range of physiological pathological processes. However, the mechanism by which inhibits EMT not fully understood. In this study, we demonstrated that overexpression inhibited motility invasiveness in vitro lung metastasis vivo. addition, found couldreverse program. silencing siRNA hepatocellular carcinoma (HCC) lines enhanced expression...
Abstract Background Nuciferine (NF), extracted from the leaves of N. nucifera Gaertn , has been shown to exhibit anti-tumor and anti-viral pharmacological properties. It can also penetrate blood brain barrier (BBB). However, mechanism by which NF inhibits glioblastoma (GBM) progression is not well understood. We aimed determine effect on GBM cell lines clarify potential molecular involved. Methods U87MG U251 were used in vitro assess efficacy NF. Cytotoxicity, viability, proliferation...
<title>Abstract</title> Rational intercropping promotes crop growth, and maize is widely interplant in the field during tobacco-curing period Southwest China. However, effects of rhizosphere interactions between two crops their mechanisms nutrient uptake utilization are not clearly understood. This study aimed to analyse sufficient interaction tobacco vegetative stage on absorption utilization, growth via a pot experiment. It integrated microbiomics with targeted metabolomics explore soil...
Glioblastoma multiforme (GBM) has been considered the most aggressive glioma type.Temozolomide (TMZ) is main first-line chemotherapeutic agent for GBM.Decreased mutS homolog 6 (MSH6) expression clinically recognized as one of principal reasons GBM resistance to TMZ.However, specific functions MSH6 in GBM, addition its role mismatch repair, remain unknown.Methods: Bioinformatics were employed analyze mRNA and protein levels clinical samples predict potential cancer-promoting mechanisms...
Green synthesized 3D CuS hollow nanoflowers are for the first time proved to be a <italic>T</italic><sub>1</sub> positive MRI contrast agent imaging-guided thermochemotherapy.
Polydatin, extracted from Polygonum cuspidatum, is known for its anti-platelet aggregation and anti-inflammatory effects. However, studies on the association of polydatin with cancer are limited, particularly regards to epithelial-mesenchymal transition (EMT)-associated migration invasion cells. The purpose present study was reveal potential anticancer effects hepatocellular carcinoma (HCC) cells, EMT. MTT assay used determine cell viability. Migration were evaluated through wound healing...
Hepatocellular carcinoma (HCC), the sixth most common malignancy worldwide, is characterized by a dismal prognosis due to high recurrence and metastasis rates. Thus, need for development of novel chemotherapeutic drugs urgent. Cyclovirobuxine D (CVB-D), steroidal alkaloid extracted from Buxus microphylla that has been extensively used relieve symptoms cardiovascular diseases, shown promising antineoplastic effects in recent studies. However, therapeutic underlying mechanisms CVB-D on HCC...
Malignant gliomas are a group of aggressive neoplasms among human cancers. The curative effects current treatments finite for improving the prognosis patients. Hyperthermia (HT) is an effective treatment cancers; however, HT with different temperatures in MG and relevant mechanisms remain unclear. MTT assay Annexin V‑fluorescein isothiocyanate/propidium iodide staining were used investigating proliferation apoptosis C6 cells, respectively. Western blotting was applied to detect expression...
Introduction Changes in the rhizosphere microbiome and metabolites resulting from crop intercropping can significantly enhance growth. While there has been an increasing number of studies on various combinations, research tobacco maize at seedling stage remains limited. Methods This study is first to explore effects between stages, we analyzed nitrogen, phosphorus potassium nutrients soil, revealed important soil microbial community composition metabolite profiles, thereby regulating growth...
The aim of the present study was to investigate effect Forkhead family transcription factor P3 (Foxp3) knockdown on function cluster differentiation (CD)4+CD25+ regulatory T cell (Tregs) and tumor growth a hepatocellular carcinoma (HCC) mouse model. CD4+CD25+ Tregs CD4+CD25- cells were sorted from peripheral blood mononuclear (PBMCs) patients with HCC. Then, ultrasound-targeted microbubble destruction (UTMD)-mediated Foxp3-microRNA (miRNA) transfected into Tregs. Subsequently, co-cultured...