A5065429336- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Radiation Dose and Imaging
- MRI in cancer diagnosis
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Ultrasound in Clinical Applications
- Intracranial Aneurysms: Treatment and Complications
- Bone fractures and treatments
- Medical Imaging Techniques and Applications
- Lower Extremity Biomechanics and Pathologies
- Bone Tumor Diagnosis and Treatments
- Prostate Cancer Treatment and Research
- Sarcoma Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Spine and Intervertebral Disc Pathology
- Advanced Neuroimaging Techniques and Applications
- Coronary Interventions and Diagnostics
- Cerebrospinal fluid and hydrocephalus
University of Rostock
2018-2023
Krankenhaus St. Joseph-Stift Bremen
2023
University Medical Center
2018-2022
University Hospital of Basel
2021
Universität Hamburg
2021
University Medical Center Hamburg-Eppendorf
2021
Universitätsmedizin Rostock
2018-2020
München Klinik
2014-2018
Ludwig-Maximilians-Universität München
2013-2018
LMU Klinikum
2014-2018
We evaluated the accuracy of PET/CT with <sup>68</sup>Ga-PSMA-HBED-CC—a <sup>68</sup>Ga-conjugated ligand human prostate-specific membrane antigen (PSMA)—to localize cancer in prostate and surrounding tissue at initial diagnosis. <b>Methods:</b> Twenty-one patients biopsy-proven underwent <sup>68</sup>Ga-PSMA-HBED-CC (<sup>68</sup>Ga-PSMA) a median 4 d (range, 0–47 d) before radical prostatectomy. Based on 6-segment model, Gleason score proportion tumor within each segment (segmental burden,...
Background and Purpose— Vertebral artery hypoplasia (VAH) is supposed to be a risk factor for posterior circulation ischemia (PCI), particularly in the territory of inferior cerebellar (PICA). The aim our study was determine whether VAH impedes perfusion dependent PICA even absence manifest PCI. Methods— VA diameter retrospectively measured 934 consecutive patients who underwent whole-brain multimodal computed tomography because suspected stroke. defined by ≤2 mm an asymmetry ratio ≤1:1.7...
Endovascular therapy in addition to standard care (EVT+SC) has been demonstrated be more effective than SC acute ischemic large vessel occlusion stroke. Our aim was determine the cost-effectiveness of EVT+SC depending on patients' initial National Institutes Health Stroke Scale (NIHSS) score, time from symptom onset, Alberta Program Early CT Score (ASPECTS), and location.A decision model based Markov simulations estimated lifetime costs quality-adjusted life years (QALYs) associated with...
We aimed to investigate the overall prevalence and possible factors influencing occurrence of crossed cerebellar diaschisis after acute middle cerebral artery infarction using whole-brain CT perfusion. A total 156 patients with unilateral hypoperfusion territory formed study cohort; 352 without served as controls. performed blinded reading different perfusion maps for presence determined relative supratentorial reduction. Moreover, imaging patterns (location volume hypoperfusion) clinical...
The aim of the study was to determine whether automated quantification pulmonary perfused blood volume (PBV) in dual-energy computed tomography angiography (DE-CTPA) can be used assess severity chronic thromboembolic hypertension (CTEPH).Automated PBV performed 25 consecutive CTEPH patients undergoing DE-CTPA. values were correlated with cardiac index and vascular resistance quantified by right heart catheterization walking distance 6-minute walk test using Pearson's correlation coefficient...
The velocity of collateral filling can be assessed in dynamic time-resolved computed tomography (CT) angiographies and may predict initial CT perfusion (CTP) follow-up lesion size. We included all patients with an M1± internal carotid artery (ICA) occlusion imaging from existing cohort 1791 consecutive who underwent multimodal for suspected stroke. was quantified using the delay time-to-peak (TTP) enhancement M2 segment distal to occlusion. Cerebral blood volume (CBV) mean transit time...
The aim of this study was to assess the diagnostic performance a dynamic, multiphasic contrast-enhanced volume-interpolated sequence with advanced parallel imaging techniques, Dixon fat saturation, and view sharing 5 hepatic arterial subphases for detection focal liver lesions.Twenty-four consecutive patients (13 females, 11 males; mean [SD] age, 58 [15] years) lesions were included in prospective study. examination performed at 3-T magnetic resonance system (MAGNETOM Skyra; Siemens...
To evaluate the effect of automated tube voltage selection (ATVS) on radiation dose at computed tomography (CT) worldwide encompassing all body regions and types CT examinations.No patient information was accessed; therefore, institutional review board approval not sought. Data from 86 centers across world were analyzed. All interactions automatically collected transmitted to vendor during two 6-week periods immediately before 2 weeks after implementation ATVS. A total 164 323 unique studies...
Background and Purpose— Large vessel occlusion stroke leads to highly variable hyperacute infarction growth. Our aim was identify clinical imaging parameters associated with growth in patients an large of the anterior circulation. Methods— Seven hundred twenty-two consecutive acute were prospectively included our monocentric registry between 2009 2017. We selected all a circulation, documented times from symptom onset, CT perfusion on admission for analysis (N=178). Ischemic core volume...
Objectives To investigate the feasibility of high-pitch CT pulmonary angiography (CTPA) in 3rd generation dual-source (DSCT) unselected patients. Methods Forty-seven patients with suspected embolism underwent CTPA on a scanner. dose index (CTDIvol) and length product (DLP) were obtained. Objective image quality was analyzed by calculating signal-to-noise-ratio (SNR) contrast-to-noise ratio (CNR). Subjective central, lobar, segmental subsegmental level rated two experienced radiologists....
Background Recent studies have proven the effectiveness of thrombectomy up to 24 hours after stroke onset for patients with specific criteria at advanced CT or MRI. Clinical implementation treatment in this extended time window remains a challenge, as many centers do not routinely use imaging. Purpose To determine whether automated cerebral x-ray attenuation measurements noncontrast provide information on presence perfusion–defined ischemic core applied late windows thrombectomy. Materials...
The aim of this study was to assess the diagnostic performance ECG-gated non-contrast-enhanced quiescent interval single-shot (QISS) magnetic resonance angiography at a field strength 3 Tesla in patients with advanced peripheral arterial occlusive disease (PAOD).A total 21 consecutive PAOD (Fontaine stage IIb and higher) referred for (MRA) were included. Imaging performed on T whole body MR. Image quality stenosis diameter evaluated comparison contrast-enhanced continuous table TWIST MRA...
<h3>BACKGROUND AND PURPOSE:</h3> Collateral blood flow is an important prognostic marker in the acute stroke situation but approaches for assessment vary widely. Our aim was to compare strategies of collateral dynamic and conventional CTA their ability predict follow-up infarction volume. <h3>MATERIALS METHODS:</h3> We retrospectively included all patients with M1 occlusion from existing cohort 1912 consecutive who underwent initial multimodal CT MR imaging or nonenhanced CT....
Crossed cerebellar diaschisis (CCD) is the phenomenon of hypoperfusion and hypometabolism contralateral hemisphere caused by dysfunction related supratentorial region. Our aim was to analyze its influence on morphologic functional outcome in acute ischemic stroke. Subjects with stroke a large vessel occlusion anterior circulation were selected from an initial cohort 1644 consecutive patients who underwent multiparametric CT including whole-brain perfusion. Two experienced readers evaluated...
Prostate cancer (PCa) is a genetically heterogeneous entity that causes challenges in pre-treatment clinical evaluation, such as the correct identification of tumor stage. Conventional tests based on digital rectal examination, Prostate-Specific Antigen (PSA) levels, and Gleason score still lack accuracy for stage prediction. We hypothesize unraveling molecular mechanisms underlying PCa staging via integrative analysis multi-OMICs data could significantly improve prediction pathological...