A5100347096- Clostridium difficile and Clostridium perfringens research
- Gut microbiota and health
- Gastrointestinal motility and disorders
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Helicobacter pylori-related gastroenterology studies
- Microscopic Colitis
- Antimicrobial Resistance in Staphylococcus
- Nosocomial Infections in ICU
- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Clinical Nutrition and Gastroenterology
- Diagnosis and treatment of tuberculosis
- Botulinum Toxin and Related Neurological Disorders
Shandong Agricultural University
2023-2024
Jilin University
2023
Rutgers, The State University of New Jersey
2022
Robert Wood Johnson University Hospital
2022
Shenzhen Institutes of Advanced Technology
2021
Chinese Academy of Sciences
2021
Columbia University Irving Medical Center
2018-2019
Shanghai Institute of Nutrition and Health
2017
Dalian Medical University
2015
Second Affiliated Hospital of Jilin University
2015
Fecal microbiota transplantation (FMT) is a promising therapy, despite some reports of adverse side effects. Bacterial consortia (BCT) for targeted restoration the intestinal ecosystem considered relatively safe and simple procedure. However, no systematic research has assessed effects FMT BCT on immune responses mucosal barrier in patients. We conducted complementary studies animal models BCT, provide recommendations improving clinical outcomes these treatments. To establish dysbiosis...
Abstract Background Guidelines recommend adding intravenous (IV) metronidazole to oral vancomycin for fulminant Clostridioides difficile infection (CDI). In this study, we compared dual therapy with IV and vs monotherapy. We assessed prevalence of use effectiveness in nonfulminant CDI. Methods This was a 2-center retrospective study conducted from 2010 2018. Adult inpatients were included if they had positive C. polymerase chain reaction (PCR) performed on an unformed stool received within 2...
Abstract Background Clostridium perfringens (Cp) is a Gram-positive anaerobic bacterium that causes necrotic enteritis (NE) in poultry when it overgrows the small intestine. NE disease has previously been controlled through use of growth-promoting antibiotics. This practice was recently banned European countries, leading to significantly increased incidence threatening industry. Control strategies and technology as substitutes dietary antibiotics are therefore urgently required. To develop...
Clostridium perfringens is a zoonotic opportunistic pathogen that produces toxins can cause necrotic enteritis and even "sudden death disease". This bacterium widely distributed in the intestines of livestock human, but there are few reports distribution aquatic animals (Hafeez et al., 2022). In order to explore isolation rate C. toxin genes they carry, 141 samples, including clams (Clam), oysters (Ostreidae), mud snails (Bullacta exerata Philippi), were collected from coastal areas Shandong...
Clostridium perfringens is a zoonotic conditional pathogen, producing toxins that can cause necrotic enteritis and even "sudden death disease". This bacterium widely distributed in the intestines of livestock human animals, but there are few reports distribution aquatic animals. In order to explore isolation rate C. its carrying toxin genes, 141 samples, including clams, oysters, mud snails, were collected from coastal areas Shandong Province, China. Cp. strains tested for cpa, cpb, etx,...
Introduction:Clostridium difficile infection (CDI) is the leading cause of healthcare-associated diarrhea and gastroenteritis-associated death. Secondary bile acids inhibit C. germination in vitro confer resistance to CDI animals. Cholecystectomy (CCY) alters gut acid composition, with increased fecal levels secondary acids. This study tested hypothesis that remote CCY confers protection against by increasing Methods: was a retrospective case control study. The population included all adult...
Background and AimsClostridioides difficile infection (CDI) is associated with a range of outcomes, existing prediction models for death among patients CDI are imprecise. Peripheral eosinopenia has been proposed as novel risk factor but not incorporated into models. This study aimed to develop validate model hospitalized that peripheral eosinopenia.MethodsEosinopenia was defined 0 eosinophils/μL on the soonest blood drawn within 48-hour window test (before or after). Adults were eligible if...
Abstract Fecal microbiota transplantation (FMT), a procedure in which fecal material is transferred from donor to recipient, has been increasingly used as treatment restore healthy gut microbiota. There substantial difference the composition of between young and aged hosts, but little known about whether age matching FMT recipient affects restoration long-term maintenance. In present investigation, we aimed study establishment resilience transplanted recipients. We treated naturally mice (20...