Melissa J. Chen

ORCID: 0000-0002-4569-5614
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About
Contact & Profiles
Research Areas
  • Reproductive Health and Contraception
  • Maternal and fetal healthcare
  • Maternal and Perinatal Health Interventions
  • Ectopic Pregnancy Diagnosis and Management
  • Breastfeeding Practices and Influences
  • Pregnancy and Medication Impact
  • Global Maternal and Child Health
  • Maternal Mental Health During Pregnancy and Postpartum
  • Gestational Trophoblastic Disease Studies
  • Sexual function and dysfunction studies
  • Ovarian function and disorders
  • Prenatal Substance Exposure Effects
  • Diversity and Career in Medicine
  • Child Nutrition and Water Access
  • Pregnancy and preeclampsia studies
  • Birth, Development, and Health
  • Endometriosis Research and Treatment
  • Pharmacological Effects and Toxicity Studies
  • Food Security and Health in Diverse Populations
  • Menstrual Health and Disorders
  • Primary Care and Health Outcomes
  • Hemoglobinopathies and Related Disorders
  • Uterine Myomas and Treatments
  • Menopause: Health Impacts and Treatments
  • Thyroid Disorders and Treatments

University of California, Davis
2016-2025

Stanford University
2023

University of Ottawa
2023

Friends Research Institute
2022

California State University, Sacramento
2021-2022

Cincinnati Children's Hospital Medical Center
2022

University of Cincinnati
2022

University of Illinois Urbana-Champaign
2022

Office of Dietary Supplements
2022

Eunice Kennedy Shriver National Institute of Child Health and Human Development
2017-2022

OBJECTIVE: To estimate whether postpartum visit attendance was improved in women exposed to a patient navigation program compared with those who received care immediately before the program's initiation and assess other health behaviors during intervention period. METHODS: This is prospective observational study of enrolled receiving program. Navigating New Motherhood for adult, English-speaking prenatal at Medicaid-based university clinic. In 2015, introduced clinic-level change which...

10.1097/aog.0000000000001977 article EN Obstetrics and Gynecology 2017-04-06

ObjectiveTo assess efficacy, cycle control, and safety of an oral contraceptive containing estetrol (E4) 15 mg drospirenone (DRSP) 3 mg.Study designWomen aged 16 to 50 years with a body mass index ≤35 kg/m2 enrolled in this multicenter, open-label, 13-cycle, phase trial evaluating E4/DRSP 24-active/4-placebo regimen. Follow-up was scheduled at Cycles 2, 4, 7, 10 within weeks completing Cycle 13. Participants used daily diaries record pill use vaginal bleeding. We evaluated efficacy outcomes...

10.1016/j.contraception.2021.05.002 article EN cc-by Contraception 2021-05-15

Objective: To assess the effects of prenatal counseling about maternal health benefits lactation on postpartum knowledge, breastfeeding intentions, and infant feeding behaviors. Materials Methods: We conducted a randomized trial with 411 nulliparous U.S.-born women carrying singleton gestation. Participants were recruited online; after completing baseline survey that assessed knowledge participants to receive 10-minute virtual session or attention-control smoke-free homes. collected data...

10.1089/bfm.2023.0219 article EN Breastfeeding Medicine 2024-01-01

The etonogestrel implant is known to have high contraceptive efficacy for up 5 years. This case report describes failure during year 4 of use in a patient with normal body mass index. was receiving thyroid hormone replacement after thyroidectomy and found iatrogenic thyrotoxicosis the months preceding pregnancy. Further study effects on metabolism are indicated.

10.1016/j.crwh.2025.e00687 article EN cc-by Case Reports in Women s Health 2025-01-18

Background: Despite health benefits to both infants and mothers, many are not breastfeeding as recommended by national guidelines. Prior studies examining the effects of housing insecurity food on intention duration have been limited yielded mixed findings. Methods: To assess relationship among insecurity, breastfeeding, we conducted a secondary analysis cohort nulliparous U.S.-born pregnant individuals with singleton gestation ≥28 weeks who completed web-based surveys five occasions over...

10.1089/jwh.2024.0346 article EN Journal of Women s Health 2025-01-20

The objective of our study was to determine if placental MRI examinations performed for the detection abnormal placentation earlier than 24 weeks' gestational age (GA) are more or less reliable at a later GA.Two radiologists blinded clinical, surgical, and pathologic reports retrospectively independently reviewed 69 nine imaging signs associated with placentation. A consensus suspicion (including accreta, increta, percreta) determined using 5-point (low high suspicion) Likert scale compared...

10.2214/ajr.14.14134 article EN American Journal of Roentgenology 2015-08-21

OBJECTIVE: To estimate the efficacy and safety of mifepristone antagonization with high-dose oral progesterone. METHODS: We planned to enroll 40 patients in a double-blind, placebo-controlled, randomized trial. enrolled at 44–63 days gestation ultrasound-confirmed gestational cardiac activity who were planning surgical abortion. Participants ingested 200 mg initiated progesterone 400 or placebo 24 hours later twice daily for 3 days, then once until their abortion 14–16 after enrollment....

10.1097/aog.0000000000003620 article EN Obstetrics and Gynecology 2019-12-03

In 2008, a large Salmonella outbreak caused by contamination of the municipal drinking water supply occurred in Alamosa, Colorado. The objectives this assessment were to determine full economic costs associated with and long-term health impacts on community Alamosa. We conducted postal survey City Alamosa (2008 population: 8,746) households businesses, in-depth interviews local, state, nongovernmental agencies, healthcare facilities schools assess outbreak. Twenty-one percent household...

10.1371/journal.pone.0057439 article EN cc-by PLoS ONE 2013-03-18

Davis, institutional review board determined that this cross-sectional study was not human participants research; therefore, it

10.1001/jamanetworkopen.2021.9219 article EN cc-by-nc-nd JAMA Network Open 2021-05-19

To describe experiences with abortion counseling and access in patients lethal or life-limiting fetal diagnoses Texas after enactment of Senate Bill 8 (SB8).In this qualitative study, we interviewed who obtained abortions SB8, using semi-structured interviews to explore how restrictions affected care. Two researchers coded all transcripts an inductive technique analyzed themes iterative approach.We 16 participants reported gestational durations from 13 29 weeks at the time abortion....

10.1097/aog.0000000000005071 article EN Obstetrics and Gynecology 2023-02-02

Deep etonogestrel contraceptive implant placements still occur despite design modifications to the inserter. We present a method for outpatient removal of nonpalpable using preprocedure ultrasonography localization followed by with modified vasectomy clamp, modification "U" technique six-capsule levonorgestrel removal.In women containing barium sulfate, we obtain radiographic examination confirm implant's presence in upper extremity. Using an 18-MHz linear ultrasound transducer, identify and...

10.1097/aog.0000000000001082 article EN Obstetrics and Gynecology 2015-10-07

To describe our experience with office removal of nonpalpable contraceptive implants at referral center.We performed a retrospective cohort study by reviewing the charts patients referred to family planning specialty center for or complex implant from January 2015 through December 2018. We localized using high-frequency ultrasonography and skin mapping in radiology, followed attempted local anesthesia modified vasectomy clamp. abstracted information on demographics, location, outcomes.Of 61...

10.1097/aog.0000000000003457 article EN Obstetrics and Gynecology 2019-09-10

To evaluate overall and subgroup efficacy of an estetrol (E4) 15 mg drospirenone (DRSP) 3 oral contraceptive in a 24/4-day regimen.We pooled outcomes from 2 pivotal phase trials with E4/DRSP conducted the United States/Canada Europe/Russia. We assessed Pearl Index (PI; pregnancies per 100 participant-years) 13-cycle life-table pregnancy rates at-risk cycles (confirmed intercourse no other use) among participants 16 to 35 years. calculated PI by age further subcategorization (contraceptive...

10.1016/j.contraception.2022.07.009 article EN cc-by Contraception 2022-07-31

To estimate the effects on cervical mucus, ovarian activity and theoretical contraceptive protection of a 6-hour delay missing one norgestrel 0.075 mg progestogen-only pill.In prospective, two-site, randomized, crossover study, healthy women aged 18 to 35 with BMI <32.0 kg/m² regular ovulatory cycles completed baseline 28-day cycle correct daily pill use followed by two intervention in which, around mid-cycle, was taken 6 hours late or missed completely. We undertook ultrasonography,...

10.1016/j.contraception.2022.09.002 article EN cc-by-nc-nd Contraception 2022-09-18

In this review, we discuss the efficacy, safety, and benefits of four new contraceptive products available in USA, specifically Annovera, Phexxi, Slynd, Twirla. Annovera is a vaginal ring releasing ethinyl estradiol segesterone acetate that can be used for up to one year (13 cycles), offering patients an effective, user-controlled option may improve access those low-resource settings or with barriers retrieving monthly prescriptions; however, given limited efficacy safety data people body...

10.1007/s13669-021-00321-4 article EN cc-by Current Obstetrics and Gynecology Reports 2022-01-06

Objective To evaluate whether scheduling a 2- to 3-week versus 6-week postpartum visit results in higher attendance. Study Design We conducted secondary analysis of quasi-experimental before–after study compare attendance after changing routine visits from 6 weeks 2 3 delivery. Secondary outcomes include patient satisfaction and breastfeeding continuation at months postpartum. collected information through chart review telephonic interviews assess with timing status. performed multivariable...

10.1055/s-0038-1675623 article EN American Journal of Perinatology 2018-11-10

Correct and consistent use of contraception decreases the risk unintended pregnancy; yet, outdated policies or practices can delay initiation hinder continuation contraceptive methods. To promote quality of, access to, family planning services, WHO created a series evidence-based guidance documents for planning, known as WHO's Four Cornerstones Family Planning Guidance (Fig. 1). The Medical eligibility criteria (MEC), first published in 1996,1 provides on safety various methods users with...

10.1002/ijgo.12064 article EN cc-by-nc-nd International Journal of Gynecology & Obstetrics 2016-12-13
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